Results 191 to 200 of about 6,102 (207)

Loss of renal tubular G9a benefits acute kidney injury by lowering focal lipid accumulation via CES1

EMBO Reports, 2023
Dong Yang, Yuchen Chen, Qing Wang
exaly  

Effect of CES1 genetic variation on enalapril steady‐state pharmacokinetics and pharmacodynamics in healthy subjects

British Journal of Clinical Pharmacology, 2021
Lucy H Her, Xinwen Wang, Jian Shi
exaly  

P186 - pH dependent CES1 mediated hydrolysis of vixotrigine in human liver microsomes

Drug Metabolism and Pharmacokinetics, 2020
Joshua Johnson, Michael Rooney, Chungang Gu   +2 more
openaire   +1 more source

Hormetic effects of EGC and EGCG on CES1 activity and its rescue from oxidative stress in rat liver S9

Chemico-Biological Interactions, 2023
Xiaoting Luo, 志芸 周
exaly  

A Comprehensive Functional Assessment of CES1 Nonsynonymous Variants

The FASEB Journal, 2017
Xinwen Wang, Nada Rida, Jian Shi, Hao‐Jie Zhu   +3 more
openaire   +1 more source

CES1 DEFICIENCY IS ASSOCIATED WITH METABOLIC REPROGRAMING AND ENDOTHELIAL DYSFUNCTION IN PULMONARY ARTERIAL HYPERTENSION

Background: Pulmonary arterial hypertension (PAH) is a progressive disease characterized by pulmonary microvascular loss and obliterative remodeling, driven by metabolic reprogramming, oxidative stress, and endothelial dysfunction. While BMPR2 mutations contribute to metabolic shifts in pulmonary microvascular endothelial cells (PMVECs), their low ...
Stuti Agarwal, Lyong Heo, Ananya Chakraborty, Ankita Mitra, Lichao Liu, Natasha Auer, Gowri Swaminathan, Flora Huang, Prakash Chelladurai, Eleana Guardado, Juan Matos, Anuradha Bankar, Crystal Le, James West, Karthik Suresh, Ramesh V Nair, Marlene Rabinovitch, Bruce D. Hammock, Christophe Morisseau, Joseph C Wu, Zoltan Arany, Mark R. Nicolls, Vinicio A. de Jesus Perez   +22 more
openaire   +1 more source

The impact of ABCB1 and CES1 polymorphisms on dabigatran pharmacokinetics and pharmacodynamics in patients with atrial fibrillation

British Journal of Clinical Pharmacology, 2021
Qing Xu, Qianzhou Lv
exaly  

The Distribution of the Genotypes of ABCB1 and CES1 Polymorphisms in Kazakhstani Patients with Atrial Fibrillation Treated with DOAC

Genes, 2023
Ayan S Abdrakhmanov, Ainur R Akilzhanova
exaly  

The Influence of the CES1 Genotype on the Pharmacokinetics of Enalapril in Patients with Arterial Hypertension

Journal of Personalized Medicine, 2022
Anna Ikonnikova, Evgeny Melnikov, Tatiana Nasedkina   +2 more
exaly  

An in vitro evaluation of kratom (Mitragyna speciosa) on the catalytic activity of carboxylesterase 1 (CES1)

Chemico-Biological Interactions, 2023
Sushobhan Mukhopadhyay, Philip Melchert, Kanumuri Sr Raju   +2 more
exaly