Results 91 to 100 of about 31,976 (243)
Nucleic acid sensors and programmed cell death [PDF]
, 2020 Liverpool, Layal +2 more
core +2 more sources
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.ABSTRACT Schizophrenia is a neurodevelopmental psychiatric disorder characterized by symptoms of psychosis, thought disorder, and flattened affect. Immune mechanisms are associated with schizophrenia, though the precise nature of this relationship (causal, correlated, consequential) and the mechanisms involved are not fully understood.
David Stacey +6 more
wiley +1 more source
Advanced NanoBiomed Research, EarlyView.Biomimetic microdevices are redefining anticancer drug screening by mimicking complex tumor microenvironments. This review highlights advances in microfluidic systems, cell microarrays, and in vivo‐like models, offering new insights into drug efficacy prediction and personalized medicine. The development of effective anticancer drugs remains a critical
Ching‐Te Kuo +2 more
wiley +1 more source
Arthritis &Rheumatology, EarlyView.Objective Takayasu arteritis (TAK) and giant cell arteritis (GCA), the most common forms of large‐vessel vasculitis (LVV), can result in serious morbidity. Understanding the molecular basis of LVV should aid in developing better biomarkers and treatments. Methods Plasma proteomic profiling of 184 proteins was performed in two cohorts. Cohort 1 included
Robert T. Maughan +15 more
wiley +1 more source
Biotechnology and Applied Biochemistry, EarlyView.ABSTRACT Actinobacillus succinogenes is a ruminal microorganism of biotechnological importance due to its capacity to produce succinic acid at high yields. Despite the scientific interest in this organism, molecular vehicles for the transfer and expression of genetic material are limited compared to the existing demand.
Angélica Vallejo‐Giraldo +7 more
wiley +1 more source
The Role of Wage and Skill Differences in US-German Employment Differences [PDF]
Greater job creation in the US than in Germany has often been related to greater wage dispersion coupled with less regulated labour and product markets in the US.
Richard B. Freeman, Ronald Schettkat
core
Approaches to repurposing reverse transcriptase antivirals in cancer
British Journal of Clinical Pharmacology, EarlyView.This review highlights the role of reverse transcriptase (RT) inhibition in cellular regulation associated with non‐terminal repeat retrotransposons and endogenous retroviruses. Based on their pleiotropic characteristics, RT inhibitors (RTIs) are discussed as potential anticancer agents.
Richard Head +2 more
wiley +1 more source
Antibacterial hydrogel: The sniper of chronic wounds
BMEMat, EarlyView.The treatment of chronic wounds has always been an important challenge in the medical field. We focus on hydrogels not only because they provide a moist healing environment but also because compared with traditional dressings, they can effectively prevent and treat infections, reduce wound pain and scar formation.
Shengtai Bian +6 more
wiley +1 more source
Mitophagy and cGAS–STING crosstalk in neuroinflammation
Acta Pharmaceutica Sinica BMitophagy, essential for mitochondrial health, selectively degrades damaged mitochondria. It is intricately linked to the cGAS-STING pathway, which is crucial for innate immunity. This pathway responds to mitochondrial DNA and is associated with cellular stress response.
Xiaogang Zhou +8 more
openaire +3 more sources
X‐ray controlled release strategy in cancer therapy
BMEMat, EarlyView.A comprehensive review on the design principles and current strategies of X‐ray stimulated release systems in cancer therapy, focusing on the X‐ray responsive functional groups and materials as well as discussing the advantages and current challenges of X‐ray controlled release systems in cancer therapy.
Yiling Ruan +5 more
wiley +1 more source