Results 21 to 30 of about 43,468 (306)
Türk Nöroloji Dergisi, 2022 Migraine is a neurological disorder characterized by recurrent attacks of headache usually accompanied by symptoms such as nausea, vomiting, photophobia and phonophobia. According to the Global Burden of Disease Study 2019 estimates, it affects more than
Necdet Karlı +2 more
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Recent advances in targeting calcitonin gene-related peptide for the treatment of menstrual migraine
Medicine, 2022 . Menstrual migraine (MM) has a longer duration and higher drug resistance than non-perimenstrual migraine. Calcitonin gene-related peptide (CGRP) and CGRP receptors are expressed in the peripheral and central nervous systems throughout the ...
Yan Jiang, MMed, Zhen-Lun Huang, BMed
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Serum calcitonin gene related peptide (CGRP) levels in migraine: A study on its clinical correlation and diagnostic efficacy [PDF]
Romanian Journal of Neurology, 2021 Migraine is a primary headache disorder marked by recurrent unilateral headache episodes. Calcitonin gene related peptide (CGRP) plays major role in migraine pathophysiology.
Sofia Khatoon +7 more
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Meningeal CGRP‐Prolactin Interaction Evokes Female‐Specific Migraine Behavior
Annals of Neurology, 2021 Migraine is three times more common in women. CGRP plays a critical role in migraine pathology and causes female‐specific behavioral responses upon meningeal application.
Amanda Avona +10 more
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The Management of High-Frequency Episodic and Chronic Migraines with Calcitonin Gene-Related Peptide Monoclonal Antibody [PDF]
Анналы клинической и экспериментальной неврологии, 2023 Introduction. High prevalence of migraine and its impact on quality of life requires the development of original agents. In 2020, fremanezumab, a new calcitonin gene-related peptide monoclonal antibody was authorized in Russia.
Larisa A. Dobrynina +4 more
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A Female-Specific Role for Calcitonin Gene-Related Peptide (CGRP) in Rodent Pain Models
Journal of Neuroscience, 2022 We aimed to investigate a sexually dimorphic role of calcitonin gene-related peptide (CGRP) in rodent models of pain. Based on findings in migraine where CGRP has a preferential pain-promoting effect in female rodents, we hypothesized that CGRP ...
C. Paige +15 more
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Frontiers in Pharmacology, 2020 It is known that calcitonin gene-related peptide (CGRP) plays a key role in pain modulation in the brain. There are high expressions of CGRP and CGRP receptor in anterior cingulate cortex (ACC), an important brain structure in pain modulation.
Ke-Sai Hou +5 more
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Calcitonin gene-related peptide is a potential autoantigen for CD4 T cells in type 1 diabetes
Frontiers in Immunology, 2022 The calcitonin gene-related peptide (CGRP) is a 37-amino acid neuropeptide with critical roles in the development of peripheral sensitization and pain. One of the CGRP family peptides, islet amyloid polypeptide (IAPP), is an important autoantigen in type
Wei Li +9 more
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Salivary CGRP can monitor the different migraine phases: CGRP (in)dependent attacks
Cephalalgia, 2021 Background CGRP plays a key role in the transmission and modulation of nociceptive signals and is a critical component in the pathogenesis of migraine. Objective To assess saliva as a substrate to measure CGRP by comparing interictal levels in patients ...
A. Alpuente +5 more
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Inflammatory complications of CGRP monoclonal antibodies: a case series
The Journal of Headache and Pain, 2021 Background Calcitonin gene-related peptide (CGRP) is expressed throughout the body and is a known mediator of migraine, exerting this biological effect through activation of trigeminovascular, meningeal and associated neuronal pathways located in close ...
J. Ray +12 more
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