Results 101 to 110 of about 36,394 (277)

Antigiardial activity of novel triazolyl-quinolone-based chalcone derivatives:when oxygen makes the difference [PDF]

open access: yes, 2015
Giardiasis is a common diarrheal disease worldwide caused by the protozoan parasite Giardia intestinalis. It is urgent to develop novel drugs to treat giardiasis, due to increasing clinical resistance to the gold standard drug metronidazole (MTZ). New
Bahadur, Vijay   +7 more
core   +2 more sources

Synthesis and Preliminary Evaluation of Several Chalcone Derivatives as Sunscreen Compounds

open access: yesChemistry Journal of Moldova: General, Industrial and Ecological Chemistry, 2019
Four chalcone derivatives were synthesized and pre-evaluated as broad-spectrum UV protector. Chalcones 1-4 showed a wide range of UV absorbance values and moderate molar absorptivity values. Chalcones 3 and 4 showed better photostability than chalcones 1
Jumina Jumina   +7 more
doaj   +1 more source

Overexpression of a Tonoplast Malate Transporter Gene Leads to Enhanced Anthocyanin Biosynthesis in Apple

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Anthocyanins, a group of secondary metabolites synthesised in the phenylpropanoid pathway, largely determine the peel colour of fleshy fruits, but it is not known if their synthesis is linked to vacuolar malate accumulation that underlies fruit acidity.
Mengxia Zhang   +5 more
wiley   +1 more source

Rosmarinic Acid Synthase 1 Phosphorylation by SmMAPK3 Is Required for Salicylic Acid‐Induced Salvianolic Acid Accumulation in Salvia miltiorrhiza Hairy Roots

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Salvianolic acid is the main active component of Salvia miltiorrhiza and holds significant value in the clinical treatment of myocardial ischemia and hypoxia. Previous studies have shown that salicylic acid (SA) can significantly promote the accumulation of salvianolic acid, but its molecular mechanism remains incompletely understood.
Xuecui Yin   +6 more
wiley   +1 more source

Synthesis of Some Phenylpyrazolo Benzimidazolo Quinoxaline Derivatives as Potent Antihistaminic Agents

open access: yesE-Journal of Chemistry, 2010
2,3-Diphenyl quinoxaline (NI) was fused with benzimidazole (NII) by a methylene bridge, which was then allowed for acetylation. The acetylated product (NIV) was made to react with different aromatic aldehydes to give chalcones (NV1-NV5).
C. H. Sridevi   +3 more
doaj   +1 more source

Halo-Substituted Chalcones and Azachalcones-Inhibited, Lipopolysaccharited-Stimulated, Pro-Inflammatory Responses through the TLR4-Mediated Pathway

open access: yesMolecules, 2018
A series of B-ring, halo-substituted chalcones and azachalcones were synthesized to evaluate and compare their anti-inflammatory activity. Mouse BALB/c macrophage RAW 264.7 were pre-treated with 10 μg/mL of each compound for one hour before induction of ...
Tzenge-Lien Shih   +3 more
doaj   +1 more source

The Transcription Factors NFYA1 and GBF3 Jointly Regulate CHS2 to Promote Tangeretin Accumulation and Cold Tolerance in Citrus

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Tangeretin has been known as a polymethoxylated flavone conferring both phytoprotection and nutraceutical value, but cryoprotective roles and molecular regulation of tangeretin under abiotic stresses remain largely unexplored. In this study, we demonstrated that cold treatment led to greater accumulation of tangeretin and upregulation of ...
Peng Xiao   +8 more
wiley   +1 more source

Synthetic and Mechanistic Studies on the Solvent-Dependent Copper-Catalyzed Formation of Indolizines and Chalcones [PDF]

open access: yes, 2015
Copper nanoparticles supported on activated carbon have been found to catalyze the multicomponent synthesis of indolizines from pyridine-2-carbaldehyde derivatives, secondary amines, and terminal alkynes in dichloromethane; in the absence of solvent ...
Albaladejo Maricó, María José   +2 more
core   +2 more sources

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