Results 101 to 110 of about 54,606 (348)
Design and Synthesis of Pyridyl and 2-Hydroxyphenyl Chalcones with Antitubercular Activity
A focussed library of pyridyl and 2-hydroxyphenyl chalcones were synthesized and tested for growth inhibitory activity against Mycobacterium tuberculosis H37Rv, and normal and cancer breast cell lines.
Kelphina Aziafor+5 more
doaj +1 more source
Our previous work identified isoxazole-based chalcones and their dihydropyrazole derivatives as two important five-membered heterocycles having antitubercular activity.
Afzal Shaik+5 more
doaj +1 more source
Single-electron reduction of chalcones to the respective radical anions is a useful technique to activate these molecules toward subsequent transformations.
Bogdan Kurpil+2 more
semanticscholar +1 more source
Abstract Premise The floral thermal microenvironment impacts plant reproduction through its effects on gametophyte performance and plant–pollinator interactions. Color and shape are axes of floral variation that may mediate floral temperature because they affect the absorption and reflection of solar radiation, but their interactive effects are unclear.
Jennifer S. Apland+2 more
wiley +1 more source
The Plant-Derived Chalcone 2,2',5'-Trihydroxychalcone Provides Neuroprotection against Toll-Like Receptor 4 Triggered Inflammation in Microglia [PDF]
Chalcones are plant metabolites with potential for therapeutic exploitation as antioxidant, anti-inflammatory, and antiproliferative agents. Here we explored the neuroprotective effects of 2,2',5'-trihydroxychalcone (225THC), a potent antioxidant with ...
Butler, M+4 more
core +2 more sources
Enantiopure Chiral Crystals: A Powerful Tool for Absolute Asymmetric Synthesis
This review covers absolute asymmetric syntheses, which allow the preparation of enantiomerically enriched chiral compounds from achiral precursors. By exploiting the crystallization of certain compounds as a conglomerate, enantiopure chiral crystals are spontaneously obtained.
Jiacheng Li, Valérie Alezra
wiley +1 more source
Antivascular and antitumor properties of the tubulin-binding chalcone TUB091 [PDF]
We investigated the microtubule-destabilizing, vascular-targeting, anti-tumor and anti-metastatic activities of a new series of chalcones, whose prototype compound is (E)-3-(3’’-amino-4’’-methoxyphenyl)-1-(5’-methoxy-3’,4’-methylendioxyphenyl)- 2 ...
Bargsten, Katja+15 more
core +3 more sources
Antiviral effects and mechanism of Qi pi pill against influenza viruses
Qi pi pill presents anti‐influenza effect and inhibits viral replication in vitro by targeting both the viral RNA replication and the release of new viral particles. Furthermore, QPP modulates the production of proinflammatory cytokines induced by influenza infection in host cells.
Chengcheng Zhang+10 more
wiley +1 more source
Isoliquiritigenin, a Strong nod Gene- and Glyceollin Resistance- Inducing Flavonoid from Soybean Root Exudate [PDF]
Isoflavonoid signal molecules from soybean (Glycine max (L.) Merr.) seed and root exudate induce the transcription of nodulation (nod) genes in Bradyrhizobium japonicum. In this study, a new compound with symbiotic activity was isolated from soybean root
Brandt, Sebastian+3 more
core
Stereoselective photodimerisation of chalcones in the molten state [PDF]
Photodimerisations of chalcone and its derivatives in the molten state proceed efficiently and stereoselectively to give rac-anti-head-to-head dimers in all cases ...
Kato Masako+5 more
core +2 more sources