Dichloromethylation of enones by carbon nitride photocatalysis
, 2020 Small organic radicals are ubiquitous intermediates in photocatalysis and are used in organic synthesis to install functional groups and to tune electronic properties and pharmacokinetic parameters of the final molecule.
Antonietti, M. +4 more
core +1 more source
The Plant-Derived Chalcone 2,2',5'-Trihydroxychalcone Provides Neuroprotection against Toll-Like Receptor 4 Triggered Inflammation in Microglia [PDF]
, 2016 Chalcones are plant metabolites with potential for therapeutic exploitation as antioxidant, anti-inflammatory, and antiproliferative agents. Here we explored the neuroprotective effects of 2,2',5'-trihydroxychalcone (225THC), a potent antioxidant with ...
Butler, M +4 more
core +2 more sources
European Journal of Organic Chemistry, Accepted Article.A cyclobutane ring constitutes an interesting scaffold for the development of new materials and drugs. In this work we describe the [2+2] cycloaddition of chalconoid precursors bearing fluorinated and heterocyclic moieties to produce cyclobutane derivatives in solution.
Concepcion Perez-Melero +3 more
wiley +1 more source
Antimicrobial Evaluation and Synthesis of Some Phenylpyrazolo benzothiazolo quinoxaline Derivatives
E-Journal of Chemistry, 2009 2,3-Diphenyl quinoxaline (SI) was fused with 2-amino benzothiazoles (SII) by a methylene bridge, which was then allowed for acetylation. The acetylated product (SIV) was made to react with different aromatic aldehydes to give chalcones (SV1-SV5 ...
CH. Sridevi +3 more
doaj +1 more source
STIP1 drives Metabolic Reprogramming in Esophageal Squamous Cell Carcinoma via AHCY‐LDHA Axis
Exploration, EarlyView.A schematic model illustrating that LCA can inhibit ESCC growth by inhibiting the STIP1/AHCY/LDHA axis. In brief. Jin et al. demonstrated that targeting STIP1 can significantly inhibit the progression of esophageal squamous cell carcinoma. The high expression of STIP1 increased the interaction between AHCY and LDHA and then AHCY recruits PRMT3 to ...
Guoguo Jin +16 more
wiley +1 more source
E-Journal of Chemistry, 2010 2,3-Diphenyl quinoxaline (NI) was fused with benzimidazole (NII) by a methylene bridge, which was then allowed for acetylation. The acetylated product (NIV) was made to react with different aromatic aldehydes to give chalcones (NV1-NV5).
C. H. Sridevi +3 more
doaj +1 more source
CHALCONES: THE PROMISING COMPOUNDS TO PROVIDE NEW WAYS FOR CANCER TREATMENT [PDF]
, 2014 Chalcones (1,3-diphenylpropen-1-ones), a biosynthetic product of the shikimate pathway, belonging to flavanoid family are precursors of open chain flavonoids and isoflavonoids, which are abundant in edible plants.
Retno, Arianingrum
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Anticancer efficacy of phenolics based structurally related compounds and their radical scavenging action [PDF]
, 2011 Cancer, one of the leading causes of death worldwide, is an abnormal cell proliferation that fails to respond to the normal signals. In an effort to eradicate the growing menace of cancer, a clear understanding of fundamental biology and molecular ...
Arvind S. Negi +3 more
core +2 more sources
Ammoniation of Dietary Flavonoids Containing a Pyrogallol Group With Amino Acids at 37°C
Food Chemistry International, EarlyView.Scheme of reaction exploration, synthesis, structural identification, and bioactivities of ammoniated flavonoids. ABSTRACT New research shows that flavonoids containing a pyrogallol group in ring B react with amino acids at 37°C, forming ammoniated derivatives and aldehydes.
Haolin Zhang +7 more
wiley +1 more source
Synthesis and Characterisation of Multi-Ferrocenyl Compounds Containing Enone Moieties [PDF]
, 2015 Ferrocene based organometallic compounds have received intense attention in synthetic chemistry due to their increasing interest in biological, optical, and electrochemical properties.
Pandey, Annu Kumari
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