Results 31 to 40 of about 54,606 (348)

Chalcone Scaffolds, Bioprecursors of Flavonoids: Chemistry, Bioactivities, and Pharmacokinetics

open access: yesMolecules, 2021
Chalcones are secondary metabolites belonging to the flavonoid (C6-C3-C6 system) family that are ubiquitous in edible and medicinal plants, and they are bioprecursors of plant flavonoids.
Mithun Rudrapal   +7 more
doaj   +1 more source

Chalcones: A review on synthesis and pharmacological activities

open access: yesJournal of Applied Pharmaceutical Sciences, 2021
of this article was presented at CUDC consortium and Summer School Conference at Chitkara University. ____________ Goyal et al. / Journal of Applied Pharmaceutical Science 11 (Supp 1); 2021: 001-014 002 Chalcones have been known from earlier times to ...
G. Kamya   +3 more
semanticscholar   +1 more source

Synthesis, molecular docking and biochemical analysis of aminoalkylated naphthalene-based chalcones as acetylcholinesterase inhibitors

open access: yesJournal of Taibah University for Science, 2021
Twelve novel chalcones were synthesized using 2-alkyloxy-naphthaldehydes and Mannich bases of 4-hydroxyacetophenone. The chalcones were characterized using FTIR, 1D and 2D NMR and HRMS spectroscopy.
Ghadah Aljohani   +4 more
doaj   +1 more source

Stress Resistance Screen in a Human Primary Cell Line Identifies Small Molecules That Affect Aging Pathways and Extend Caenorhabditis elegans' Lifespan. [PDF]

open access: yes, 2020
Increased resistance to environmental stress at the cellular level is correlated with the longevity of long-lived mutants and wild-animal species. Moreover, in experimental organisms, screens for increased stress resistance have yielded mutants that are ...
Ang, Kenny Kean-Hooi   +5 more
core   +2 more sources

Identification and Functional Characterization of Fungal Chalcone Synthase and Chalcone Isomerase

open access: yesJournal of Natural Products, 2023
By mining fungal genomic information, a noncanonical iterative type I PKS fused with an N-terminal adenylation-thiolation didomain, which catalyzes the formation of naringenin chalcone, was found. Structural prediction and molecular docking analysis indicated that a C-terminal thioesterase domain was involved in the Claisen-type cyclization.
Sho Furumura   +7 more
openaire   +2 more sources

A Glimpse of the Molecule Chalcone

open access: yesFuture Journal of Pharmaceuticals and Health Sciences, 2021
The compound chalcone is very common which can available by synthetic means and naturally occurring from plant sources. These compounds have predominant value for their abundant properties with less adverse impacts on biological systems. The naturally occurring chalcone belongs to the flavonoid family.
Monapati Suchitra   +2 more
openaire   +2 more sources

Natural Chalcones and Derivatives in Colon Cancer: Pre-Clinical Challenges and the Promise of Chalcone-Based Nanoparticles

open access: yesPharmaceutics, 2023
Colon cancer poses a complex and substantial global health challenge, necessitating innovative therapeutic approaches. Chalcones, a versatile class of compounds with diverse pharmacological properties, have emerged as promising candidates for addressing ...
Soufyane Hba   +9 more
doaj   +1 more source

Synthesis, In Silico Studies, Antiprotozoal and Cytotoxic Activities of Quinoline‐Biphenyl Hybrids [PDF]

open access: yes, 2020
This is the pre-peer reviewed version of the following article: Synthesis, In Silico Studies, Antiprotozoal and Cytotoxic Activities of Quinoline‐Biphenyl Hybrids, which has been published in final form at https://doi.org/10.1002/slct.201903835.
Carda, Miguel   +6 more
core   +1 more source

The [4+2]‐Cycloaddition of α‐Nitrosoalkenes with Thiochalcones as a Prototype of Periselective Hetero‐Diels–Alder Reactions—Experimental and Computational Studies [PDF]

open access: yes, 2020
The [4+2]‐cycloadditions of α‐nitrosoalkenes with thiochalcones occur with high selectivity at the thioketone moiety of the dienophile providing styryl‐substituted 4H‐1,5,2‐oxathiazines in moderate to good yields.
Boger D. L.   +8 more
core   +1 more source

Chalcones in Dermatology

open access: yes, 2021
The human skin is pivotal for protecting the body from various stresses and diseases, regulating several physiological aspects, and sensing any signal changes around the environment. To work and function optimally, the skin should be protected and cared regularly by using some treatments.
Jumina   +2 more
openaire   +3 more sources

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