Results 91 to 100 of about 2,601,570 (295)
Threshold resonance and controlled filtering in quantum star graphs
, 2011 We design two simple quantum devices applicable as an adjustable quantum spectral filter and as a flux controller. Their function is based upon the threshold resonance in a F\"ul\"op-Tsutsui type star graph with an external potential added on one of the ...
Cheon, Taksu, Turek, Ondřej
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
A sodium leak current regulates pacemaker activity of adult central pattern generator neurons in Lymnaea stagnalis. [PDF]
PLoS ONE, 2011 The resting membrane potential of the pacemaker neurons is one of the essential mechanisms underlying rhythm generation. In this study, we described the biophysical properties of an uncharacterized channel (U-type channel) and investigated the role of ...
Tom Z Lu, Zhong-Ping Feng
doaj +1 more source
Radio Co-location Aware Channel Assignments for Interference Mitigation in Wireless Mesh Networks
, 2015 Designing high performance channel assignment schemes to harness the potential of multi-radio multi-channel deployments in wireless mesh networks (WMNs) is an active research domain.
Kala, Srikant Manas +3 more
core +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Firing Pattern Formation by Transient Calcium Current in Model Motoneuron
Nonlinear Analysis, 2000 Firing properties of neurons are important in signal detection and generation in nervous system. Spinal cord motoneurons have membrane properties adapted to muscle properties.
N. Svirskienė, G. Svirskis
doaj +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Sub-Nyquist Field Trial Using Time Frequency Packed DP-QPSK Super-Channel Within Fixed ITU-T Grid
, 2015 Sub-Nyquist time frequency packing technique was demonstrated for the first time in a super channel field trial transmission over long-haul distances. The technique allows a limited spectral occupancy even with low order modulation formats.
Berrettini, G. +14 more
core +1 more source
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source