Results 71 to 80 of about 2,617,838 (299)

Symmetry decomposition of potentials with channels [PDF]

open access: yesJournal of Physics A: Mathematical and General, 1997
We discuss the symmetry decomposition of the average density of states for the two dimensional potential $V=x^2y^2$ and its three dimensional generalisation $V=x^2y^2+y^2z^2+z^2x^2$. In both problems, the energetically accessible phase space is non-compact due to the existence of infinite channels along the axes.
openaire   +3 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

The TRPA1 Channel in the Cardiovascular System: Promising Features and Challenges

open access: yesFrontiers in Pharmacology, 2019
The transient receptor potential ankyrin 1 (TRPA1) channel is a calcium-permeable nonselective cation channel in the plasma membrane that belongs to the transient receptor potential (TRP) channel superfamily.
Zhen Wang   +25 more
doaj   +1 more source

Cinacalcet inhibition of neuronal action potentials preferentially targets the fast inactivated state of voltage-gated sodium channels

open access: yesFrontiers in Physiology, 2022
Voltage-gated sodium channel (VGSC) activation is essential for action potential generation in the brain. Allosteric calcium-sensing receptor (CaSR) agonist, cinacalcet, strongly and ubiquitously inhibits VGSC currents in neocortical neurons via an ...
Jamie S. Lindner   +7 more
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Information Sharing and Channel Construction of Supply Chain under Asymmetric Demand Information

open access: yesJournal of Applied Mathematics, 2014
Information sharing and marketing channel building have become an important problem of supply chain management theory and practice. The research of information sharing focused on traditional channel of supply chain between upstream and downstream ...
Guangdong Wu   +4 more
doaj   +1 more source

The effect of myocardial action potential duration on cardiac pumping efficacy: a computational study

open access: yesBioMedical Engineering OnLine, 2018
Background and aims Although studies on the relation between arrhythmias and the action potential duration (APD) have been carried out, most of them are based only on electrophysiological factors of the heart and lack experiments that consider cardiac ...
Da Un Jeong, Ki Moo Lim
doaj   +1 more source

A Formulation of the Potential for Communication Condition using C2KA

open access: yes, 2014
An integral part of safeguarding systems of communicating agents from covert channel communication is having the ability to identify when a covert channel may exist in a given system and which agents are more prone to covert channels than others. In this
Jaskolka, Jason, Khedri, Ridha
core   +2 more sources

A 64-channel, 1.1-pA-accurate on-chip potentiostat for parallel electrochemical monitoring [PDF]

open access: yes, 2019
Electrochemical monitoring is crucial for both industrial applications, such as microbial electrolysis and corrosion monitoring as well as consumer applications such as personal health monitoring.
Ceyssens, Frederik   +4 more
core   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

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