Results 51 to 60 of about 11,137,717 (304)
Kinetic model based on molecular mechanism for action potential [PDF]
, 2011 The Hodgkin-Huxley model for action potentials has been widely used but was not built on a microscopic description of the neuronal membrane. Through molecular dynamics simulations, the molecular mechanism of the channel currents is becoming clear ...
Lizhong Xu
core
PIEZO1 Channel Is a Potential Regulator of Synovial Sarcoma Cell-Viability [PDF]
, 2018 Detection of mechanical stress is essential for diverse biological functions including touch, audition, and maintenance of vascular myogenic tone. PIEZO1, a mechano-sensing cation channel, is widely expressed in neuronal and non-neuronal cells and is ...
Hiroka Suzuki +9 more
core +1 more source
Essays on Channel Deletion and Channel Contraction [PDF]
, 2022 With the advent of online, mobile, and social media channels, firms have an array of channels in their channel mix. The proliferation of channels has increased marketing costs and may be detrimental to a firm’s competitive position.
Kumar, Binay
core +1 more source
Non-equilibrium stochastic dynamics of open ion channels [PDF]
, 2013 We present and discuss a modified version of reaction rate theory (RRT) to describe the passage of a positive ion through a biological ion channel. It takes explicit account of the non-equilibrium nature of the permeation process. Unlike traditional RRT,
Kaufman, Igor +5 more
core +3 more sources
Do Magnesium Ions Have Similar Effects as Calcium Ions on Resting Membrane Potential?
MembranesMaintaining a membrane electrical potential of biological cells is a dynamic process, as some cells have a continually changing potential, like pacemaker cells, while other cells may function with large or small changes in the membrane potential ...
Anthony Hana +4 more
doaj +1 more source
Thermo-sensitive TRP channels and prevention of major chronic diseases
Di-san junyi daxue xuebao, 2022 American scientists David Julius and Ardem Patapoutian won the Nobel Prize in physiology or medicine in 2021 for their groundbreaking discoveries of capsaicin receptor TRPV1 and menthol receptor TRPM8, revealing the secrets of temperature perception. The
ZHU Zhiming, LIU Daoyan
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT The medical burdens of sickle cell disease (SCD) and transfusion‐dependent β‐thalassemia (TDT) are chronic and cumulative, even in children. Yet the effects expand beyond medications and healthcare visits due to their impacts on school attendance, academic performance, and peer engagement.
Mary Ann Etling +2 more
wiley +1 more source
Drug Design, Development and Therapy, 2020 Jin Yu, Caifeng Zhu, Jiazhen Yin, Dongrong Yu, Feng Wan, Xuanli Tang, Xue Jiang Department of Nephrology, Guangxing Hospital Affiliated to ZheJiang Chinese Medical University (Key Laboratory of Zhejiang Province, Management of Kidney Disease), Hangzhou ...
Yu J +6 more
doaj
FEBS Open Bio, 2017 Voltage‐dependent inactivation of ion channels contributes to the regulation of the membrane potential of excitable cells. Mouse polycystic kidney disease 2‐like 1 (PKD2L1) forms voltage‐dependent nonselective cation channels, which are activated but ...
Takahiro Shimizu +6 more
doaj +1 more source
Frontiers in Physiology, 2022 Cardiac fibroblasts make up a major proportion of non-excitable cells in the heart and contribute to the cardiac structural integrity and maintenance of the extracellular matrix.
Asfree Gwanyanya +2 more
doaj +1 more source