Results 31 to 40 of about 2,617,838 (299)

Alterations of Electrophysiological Properties and Ion Channel Expression in Prefrontal Cortex of a Mouse Model of Schizophrenia

open access: yesFrontiers in Cellular Neuroscience, 2019
Maternal immune activation (MIA) and juvenile social isolation (SI) are two most prevalent and widely accepted environmental insults that could increase the propensity of psychiatric illnesses.
Zhen Mi   +6 more
doaj   +1 more source

Blockade of current through single calcium channels by trivalent lanthanide cations. Effect of ionic radius on the rates of ion entry and exit. [PDF]

open access: yes, 1990
Currents flowing through single dihydropyridine-sensitive Ca2+ channels were recorded from cell-attached patches on C2 myotubes. In the presence of dihydropyridine agonist to prolong the duration of single-channel openings, adding micromolar ...
Lansman, JB
core   +2 more sources

A fast Markovian method for modeling channel noise in neurons

open access: yesHeliyon, 2023
Channel noise results from rapid transitions of protein channels from closed to open state and is generally considered as the most dominant source of electrical noise causing membrane-potential fluctuations even in the absence of synaptic inputs.
Norbert Ankri, Dominique Debanne
doaj   +1 more source

Evidence for L-dependence generated by channel coupling: 16O scattering from 12C at 115.9 MeV [PDF]

open access: yes, 2016
Background: In earlier work, inversion of S matrix for 330 MeV 16O on 12C resulted in highly undulatory potentials; the S matrix resulted from the inclusion of strong coupling to states of projectile and target nuclei.
G. R. Satchler   +2 more
core   +2 more sources

Dendritic small conductance calcium-activated potassium channels activated by action potentials suppress EPSPs and gate spike-timing dependent synaptic plasticity

open access: yeseLife, 2017
Small conductance calcium-activated potassium channels (SK channels) are present in spines and can be activated by backpropagating action potentials (APs).
Scott L Jones   +2 more
doaj   +1 more source

Structural basis of TRPC4 regulation by calmodulin and pharmacological agents

open access: yeseLife, 2020
Canonical transient receptor potential channels (TRPC) are involved in receptor-operated and/or store-operated Ca2+ signaling. Inhibition of TRPCs by small molecules was shown to be promising in treating renal diseases.
Deivanayagabarathy Vinayagam   +11 more
doaj   +1 more source

Why do platelets express K+ channels?

open access: yesPlatelets, 2021
Potassium ions have widespread roles in cellular homeostasis and activation as a consequence of their large outward concentration gradient across the surface membrane and ability to rapidly move through K+-selective ion channels.
Joy R Wright, Martyn P. Mahaut-Smith
doaj   +1 more source

Retention Characteristics and DMP Efficiency in V-NAND With Dimple Structure

open access: yesIEEE Journal of the Electron Devices Society
In this paper, we analyze the retention characteristics of vertical NAND(V-NAND) with dimpled (convex and concave) structures considering the impact of adjacent cell states.
Seongwoo Kim   +3 more
doaj   +1 more source

Deciphering the Role of Ion Channels in Early Defense Signaling against Herbivorous Insects

open access: yesCells, 2021
Plants and insect herbivores are in a relentless battle to outwit each other. Plants have evolved various strategies to detect herbivores and mount an effective defense system against them.
Akanksha Gandhi   +5 more
doaj   +1 more source

Thermo-sensitive TRP channels and prevention of major chronic diseases

open access: yesDi-san junyi daxue xuebao, 2022
American scientists David Julius and Ardem Patapoutian won the Nobel Prize in physiology or medicine in 2021 for their groundbreaking discoveries of capsaicin receptor TRPV1 and menthol receptor TRPM8, revealing the secrets of temperature perception. The
ZHU Zhiming, LIU Daoyan
doaj   +1 more source

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