Results 31 to 40 of about 11,137,717 (304)

Simulation and calculation of the contribution of hyperpolarization-activated cyclic nucleotide-gated channels to action potentials [PDF]

Archives of Biological Sciences, 2016
The hyperpolarization-activated cyclic nucleotide-gated (HCN) channel, which mediates the influx of cations, has an important role in action potential generation.
Liao Liping, Lin Xianguang, Hu Jielin, Wu Xin, Yang Xiaofei, Wang Wei, Li Chenhong   +6 more
doaj   +1 more source

Remodelling of human atrial K+ currents but not ion channel expression by chronic β-blockade [PDF]

, 2011
Chronic β-adrenoceptor antagonist (β-blocker) treatment in patients is associated with a potentially anti-arrhythmic prolongation of the atrial action potential duration (APD), which may involve remodelling of repolarising K+ currents.
Currie, S., Tellez, James O, Julie A. Russell, Kane, Kathleen A, Jhund, Pardeep S, Boyett, M.R., Rankin, A.C., Pardeep S. Jhund, Mark R. Boyett, Dempster, John, Marshall, Gillian E., John Dempster, Currie, Susan, Russell, J.A., Workman, Antony J., Marshall, Gillian E, Workman, A.J., Marshall, G.E., Russell, Julie A, Dempster, J., Rankin, Andrew C, Russell, Julie A., Gillian E. Marshall, Tellez, James O., Boyett, Mark R, Kathleen A. Kane, Boyett, Mark R., Andrew C. Rankin, Rankin, Andrew C., Kane, K.A., Workman, Antony J, Tellez, J.O., Antony J. Workman, Kane, Kathleen A., Jhund, P.S., Susan Currie, James O. Tellez, Jhund, Pardeep S.   +37 more
core   +1 more source

The Emerging Chondrocyte Channelome

Frontiers in Physiology, 2010
Chondrocytes are the resident cells of articular cartilage and are responsible for synthesising a range of collagenous and non-collagenous extracellular matrix macromolecules.
Richard Barrett-Jolley, Rebecca Lewis, Rebecca Fallman, Ali Mobasheri   +3 more
doaj   +1 more source

Reduced TRPC channel expression in psoriatic keratinocytes is associated with impaired differentiation and enhanced proliferation [PDF]

, 2011
Psoriasis is a characteristic inflammatory and scaly skin condition with typical histopathological features including increased proliferation and hampered differentiation of keratinocytes.
Ute Woelfle, Kristina Leuner, Schempp, Christoph M., Kraus, Margarethe, Walter E Müller, Harteneck Christian, Christoph M. Schempp, Walter E. Müller, Margarethe Kraus, Harteneck, Christian, Beschmann, Heike, Beschmann, Heike A., Boehncke, Wolf-Henning, Beschmann Heike, Boehncke Wolf-Henning, Schempp Christoph M., Kraus Margarethe, Christoph M Schempp, Schempp, Christoph Mathis, Wolf-Henning Boehncke, Heike Beschmann, Christian Harteneck, Woelfle Ute, Leuner Kristina, Leuner, Kristina, Wölfle, Ute, Müller Walter E., Woelfle, Ute, Müller, Walter E.   +28 more
core   +1 more source

Alterations of Electrophysiological Properties and Ion Channel Expression in Prefrontal Cortex of a Mouse Model of Schizophrenia

Frontiers in Cellular Neuroscience, 2019
Maternal immune activation (MIA) and juvenile social isolation (SI) are two most prevalent and widely accepted environmental insults that could increase the propensity of psychiatric illnesses.
Zhen Mi, Jun Yang, Quansheng He, Xiaowen Zhang, Yujie Xiao, Yousheng Shu, Yousheng Shu   +6 more
doaj   +1 more source

Pannexin1 channels—a potential therapeutic target in inflammation

Frontiers in Cell and Developmental Biology, 2022
An exaggerated inflammatory response is the hallmark of a plethora of disorders. ATP is a central signaling molecule that orchestrates the initiation and resolution of the inflammatory response by enhancing activation of the inflammasome, leukocyte recruitment and activation of T cells. ATP can be released from cells through pannexin (Panx) channels, a
Olga M. Rusiecka, Olga M. Rusiecka, Malaury Tournier, Malaury Tournier, Filippo Molica, Filippo Molica, Brenda R. Kwak, Brenda R. Kwak   +7 more
openaire   +3 more sources

Dendritic small conductance calcium-activated potassium channels activated by action potentials suppress EPSPs and gate spike-timing dependent synaptic plasticity

eLife, 2017
Small conductance calcium-activated potassium channels (SK channels) are present in spines and can be activated by backpropagating action potentials (APs).
Scott L Jones, Minh-Son To, Greg J Stuart   +2 more
doaj   +1 more source

The Role of Transient Receptor Potential Channel 6 Channels in the Pulmonary Vasculature [PDF]

Frontiers in Immunology, 2017
Canonical or classical transient receptor potential channel 6 (TRPC6) is a Ca2+-permeable non-selective cation channel that is widely expressed in the heart, lung, and vascular tissues. The use of TRPC6-deficient ("knockout") mice has provided important insights into the role of TRPC6 in normal physiology and disease states of the pulmonary vasculature.
Malczyk, Monika, Erb, Alexandra, Veith, Christine, Ghofrani, Hossein Ardeschir, Schermuly, Ralph T., Gudermann, Thomas, Dietrich, Alexander, Weissmann, Norbert, Sydykov, Akylbek   +8 more
openaire   +4 more sources

Transient Receptor Potential Cation Channels in Disease [PDF]

Physiological Reviews, 2007
The transient receptor potential (TRP) superfamily consists of a large number of cation channels that are mostly permeable to both monovalent and divalent cations. The 28 mammalian TRP channels can be subdivided into six main subfamilies: the TRPC (canonical), TRPV (vanilloid), TRPM (melastatin), TRPP (polycystin), TRPML (mucolipin), and the TRPA ...
Nilius, Bernd, Owsianik, Grzegorz, Voets, Thomas, Peters, John A.   +3 more
openaire   +2 more sources

Sales promotions and channel coordination [PDF]

, 2009
Consumer sales promotions are usually the result of the decisions of two marketing channel parties, the manufacturer and the retailer. In making these decisions, each party normally follows its own interest: i.e. maximizes its own profit.
Wierenga, B., Soethoudt, J.M., Soethoudt, H, Wierenga, B. (Berend), Soethoudt, H. (Han), Han Soethoudt, Wierenga, Berend, Berend Wierenga   +7 more
core   +1 more source