Influence of bottom topography on integral constraints in zonal flows with parameterized potential vorticity fluxes [PDF]
, 2013 An integral constraint for eddy fluxes of potential vorticity (PV), corresponding to global momentum conservation, is applied to two-layer zonal quasi-geostrophic channel flow. This constraint must be satisfied for any type of parameterization of eddy PV
Zalesny, V.B. +4 more
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Classical Transient Receptor Potential 1 (TRPC1): Channel or Channel Regulator?
Cells, 2014 In contrast to other Classical Transient Receptor Potential TRPC channels the function of TRPC1 as an ion channel is a matter of debate, because it is often difficult to obtain substantial functional signals over background in response to over-expression
Alexander Dietrich +2 more
doaj +1 more source
Single-channel measurements of an N-acetylneuraminic acid-inducible outer membrane channel in Escherichia coli [PDF]
, 2012 NanC is an Escherichia coli outer membrane protein involved in sialic acid (Neu5Ac, i.e., N-acetylneuraminic acid) uptake. Expression of the NanC gene is induced and controlled by Neu5Ac. The transport mechanism of Neu5Ac is not known.
Peneff, Caroline M. +4 more
core +1 more source
Extracellular blockade of K(+) channels by TEA : results from molecular dynamics simulations of the KcsA channel [PDF]
, 2001 TEA is a classical blocker of K(+) channels. From mutagenesis studies, it has been shown that external blockade by TEA is strongly dependent upon the presence of aromatic residue at Shaker position 449 which is located near the extracellular entrance to ...
Simon Bernèche +5 more
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Embedding potential definition of channel functions [PDF]
Physical Review B, 2005 14 pages, 2 ...
Inglesfield, J E, Crampin, S, Ishida, H
openaire +2 more sources
Simulation and calculation of the contribution of hyperpolarization-activated cyclic nucleotide-gated channels to action potentials [PDF]
Archives of Biological Sciences, 2016 The hyperpolarization-activated cyclic nucleotide-gated (HCN) channel, which mediates the influx of cations, has an important role in action potential generation.
Liao Liping +6 more
doaj +1 more source
Remodelling of human atrial K+ currents but not ion channel expression by chronic β-blockade [PDF]
, 2011 Chronic β-adrenoceptor antagonist (β-blocker) treatment in patients is associated with a potentially anti-arrhythmic prolongation of the atrial action potential duration (APD), which may involve remodelling of repolarising K+ currents.
Currie, S. +37 more
core +1 more source
Transient Receptor Potential (TRP) Channels [PDF]
, 2018 Transient Receptor Potential (TRP) channels are evolutionarily conserved integral membrane proteins. The mammalian TRP superfamily of ion channels consists of 28 cation permeable channels that are grouped into six subfamilies based on sequence homology (Fig. 6.1).
Amrita, Samanta +2 more
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Natural channel protein inserts and functions in a completely artificial, solid-supported bilayer membrane [PDF]
, 2013 Reconstitution of membrane proteins in artificial membrane systems creates a platform for exploring their potential for pharmacological or biotechnological applications.
Fu, Wangyang +3 more
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The Emerging Chondrocyte Channelome
Frontiers in Physiology, 2010 Chondrocytes are the resident cells of articular cartilage and are responsible for synthesising a range of collagenous and non-collagenous extracellular matrix macromolecules.
Richard Barrett-Jolley +3 more
doaj +1 more source