TRP channels as potential drug targets [PDF]
Biology of the Cell, 2004 Abstract Calcium (Ca2+) is an ubiquitous intracellular signal that is responsible for a plethora of cellular processes including fertilization, secretion, contraction, neuronal signaling and learning. In addition, changes in intracellular Ca2+ have been known to influence cell proliferation and differentiation for more than three decades.
Ulrich, Wissenbach +2 more
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Classical Transient Receptor Potential 1 (TRPC1): Channel or Channel Regulator?
Cells, 2014 In contrast to other Classical Transient Receptor Potential TRPC channels the function of TRPC1 as an ion channel is a matter of debate, because it is often difficult to obtain substantial functional signals over background in response to over-expression
Alexander Dietrich +2 more
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Complete elimination of information leakage in continuous-variable quantum communication channels [PDF]
, 2018 In all lossy communication channels realized to date, information is inevitably leaked to a potential eavesdropper. Here we present a communication protocol that does not allow for any information leakage to a potential eavesdropper in a purely lossy ...
Andersen, Ulrik L. +4 more
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Steric-effect-induced enhancement of electrical-double-layer overlapping phenomena\ud [PDF]
, 2011 In this paper, we demonstrate that nontrivial interactions between steric effect and electrical-double-layer (EDL) overlap phenomena may augment the effective extent of EDL overlap in narrow fluidic confinements to a significant extent by virtue of ...
Chakraborty, Suman, Das, Siddhartha
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Simulation and calculation of the contribution of hyperpolarization-activated cyclic nucleotide-gated channels to action potentials [PDF]
Archives of Biological Sciences, 2016 The hyperpolarization-activated cyclic nucleotide-gated (HCN) channel, which mediates the influx of cations, has an important role in action potential generation.
Liao Liping +6 more
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Channel inhibitor shows antidepressant potential [PDF]
Nature Reviews Drug Discovery, 2009 openaire +3 more sources
Feshbach resonances with large background scattering length: interplay with open-channel resonances [PDF]
, 2004 Feshbach resonances are commonly described by a single-resonance Feshbach model, and open-channel resonances are not taken into account explicitly. However, an open-channel resonance near threshold limits the range of validity of this model.
Kokkelmans, S. J. J. M. F. +3 more
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Particle transport across a channel via an oscillating potential [PDF]
, 2017 Membrane protein transporters alternate their substrate-binding sites between the extracellular and cytosolic side of the membrane according to the alternating access mechanism.
Dagdug, Leonardo +4 more
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The Emerging Chondrocyte Channelome
Frontiers in Physiology, 2010 Chondrocytes are the resident cells of articular cartilage and are responsible for synthesising a range of collagenous and non-collagenous extracellular matrix macromolecules.
Richard Barrett-Jolley +3 more
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Transient Receptor Potential Cation Channels in Disease [PDF]
Physiological Reviews, 2007 The transient receptor potential (TRP) superfamily consists of a large number of cation channels that are mostly permeable to both monovalent and divalent cations. The 28 mammalian TRP channels can be subdivided into six main subfamilies: the TRPC (canonical), TRPV (vanilloid), TRPM (melastatin), TRPP (polycystin), TRPML (mucolipin), and the TRPA ...
Nilius, Bernd +3 more
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