Results 11 to 20 of about 11,137,717 (304)

Potential Capacities of Quantum Channels [PDF]

open access: yesIEEE Transactions on Information Theory, 2016
10 pages, IEEE style; minor changes, references added; accepted for publication in EEE Trans Inf ...
Andreas J. Winter 0002, Dong Yang
openaire   +3 more sources

Pulmonary vasoconstrictor action of KCNQ potassium channel blockers [PDF]

open access: yes, 2006
KCNQ channels have been widely studied in the nervous system, heart and inner ear, where they have important physiological functions. Recent reports indicate that KCNQ channels may also be expressed in portal vein where they are suggested to influence ...
Joshi, Shreena   +2 more
core   +5 more sources

Eag1 Channels as Potential Cancer Biomarkers [PDF]

open access: yesSensors, 2012
Cancer is a leading cause of death worldwide. New early tumor markers are needed to treat the disease at curable stages. In addition, new therapeutic targets are required to treat patients not responding to available treatments. Ion channels play major roles in health and disease, including cancer.
Javier Camacho   +2 more
openaire   +4 more sources

Sodium channels amplify spine potentials [PDF]

open access: yesProceedings of the National Academy of Sciences, 2007
Dendritic spines mediate most excitatory synapses in the brain. Past theoretical work and recent experimental evidence have suggested that spines could contain sodium channels. We tested this by measuring the effect of the sodium channel blocker tetrodotoxin (TTX) on depolarizations generated by two-photon uncaging of glutamate on spines from mouse ...
Araya, Roberto   +3 more
openaire   +3 more sources

TRP channels as potential drug targets [PDF]

open access: yesBiology of the Cell, 2004
Abstract Calcium (Ca2+) is an ubiquitous intracellular signal that is responsible for a plethora of cellular processes including fertilization, secretion, contraction, neuronal signaling and learning. In addition, changes in intracellular Ca2+ have been known to influence cell proliferation and differentiation for more than three decades.
Ulrich, Wissenbach   +2 more
openaire   +2 more sources

Oncogenic potential of EAG K+ channels [PDF]

open access: yesThe EMBO Journal, 1999
We have investigated the possible implication of the cell cycle-regulated K(+) channel ether à go-go (EAG) in cell proliferation and transformation. We show that transfection of EAG into mammalian cells confers a transformed phenotype. In addition, human EAG mRNA is detected in several somatic cancer cell lines, despite being preferentially expressed ...
L A, Pardo   +6 more
openaire   +3 more sources

Transient Receptor Potential Channels and Itch

open access: yesInternational Journal of Molecular Sciences, 2022
Transient Receptor Potential (TRP) channels are multifunctional sensory molecules that are abundant in the skin and are involved in the sensory pathways of itch, pain, and inflammation. In this review article, we explore the complex physiology of different TRP channels, their role in modulating itch sensation, and their contributions to the ...
Mahmoud, Omar   +2 more
openaire   +2 more sources

A KATP channel opener inhibited myocardial reperfusion action potential shortening and arrhythmias [PDF]

open access: yes, 2001
Low concentrations of certain K<sub>ATP</sub> channel openers have been reported to exert a moderate inhibitory effect on arrhythmias during post-ischaemic early myocardial reperfusion, but the accompanying effects on the time course of ...
Northover, B.J.   +5 more
core   +1 more source

A novel ion channel formed by interaction of TRPML3 with TRPV5. [PDF]

open access: yes, 2013
TRPML3 and TRPV5 are members of the mucolipin (TRPML) and TRPV subfamilies of transient receptor potential (TRP) cation channels. Based on sequence similarities of the pore forming regions and on structure-function evidence, we hypothesized that the pore
Becker, Lars   +19 more
core   +2 more sources

Influence of bottom topography on integral constraints in zonal flows with parameterized potential vorticity fluxes [PDF]

open access: yes, 2013
An integral constraint for eddy fluxes of potential vorticity (PV), corresponding to global momentum conservation, is applied to two-layer zonal quasi-geostrophic channel flow. This constraint must be satisfied for any type of parameterization of eddy PV
Zalesny, V.B.   +4 more
core   +1 more source

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