Results 91 to 100 of about 2,617,838 (299)

Electronic transport of bilayer graphene with asymmetry line defects

, 2016
In this paper, we study the quantum properties of a bilayer graphene with (asymmetry) line defects. The localized states are found around the line defects.
Chen, Chan, Kou, Su-Peng, Liang, Ying, Wu, Ya-Jie, Zhao, Xiao-Ming   +4 more
core   +1 more source

Charge fluctuations and boundary conditions of biological ion channels:effect on the ionic transition rate [PDF]

, 2009
A self-consistent solution is derived for the Poisson-Nernst-Planck (PNP) equation, valid both inside a biological ion channel and in the adjacent bulk fluid. An iterative procedure is used to match the two solutions together at the channel mouth. Charge
Eisenberg, R. S., Luchinsky, D. G., McClintock, P. V. E., Tindjong, R.   +3 more
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Meclonazepam sensitivity of parasitic flatworms correlates with TRPMMCLZ sensitivity to meclonazepam

International Journal for Parasitology: Drugs and Drug Resistance
The ionotropic portfolio of parasitic flatworms affords considerable opportunity for development of new anthelmintics. In this regard, transient receptor potential ion channels (TRP channels), cation channels responsive to various physiochemical cues ...
Claudia M. Rohr, Paul McCusker, Marc Kaethner, Rebecca Armstrong, Emily Robb, Sang-Kyu Park, Daniel J. Sprague, Aaron G. Maule, Mostafa Zamanian, Britta Lundström-Stadelmann, John D. Chan, Jonathan S. Marchant   +11 more
doaj   +1 more source

CaMKII regulation of cardiac K channels

Frontiers in Pharmacology, 2014
Cardiac K channels are critical determinants of cardiac excitability. In hypertrophied and failing myocardium, alterations in the expression and activity of voltage-gated K currents are frequently observed and contribute to the increased propensity for ...
Julian eMustroph, Lars S Maier, Stefan eWagner   +2 more
doaj   +1 more source

Radio Co-location Aware Channel Assignments for Interference Mitigation in Wireless Mesh Networks

, 2015
Designing high performance channel assignment schemes to harness the potential of multi-radio multi-channel deployments in wireless mesh networks (WMNs) is an active research domain.
Kala, Srikant Manas, Musham, Ranadheer, Reddy, M. Pavan Kumar, Tamma, Bheemarjuna Reddy   +3 more
core   +1 more source

Emergence of a secondary rainbow and the dynamical polarization potential for ¹⁶O on ¹²C at 330 MeV [PDF]

, 2015
Background: It was shown recently that an anomaly in the elastic scattering of 16O on 12C at around 300 MeV is resolved by including within the scattering model the inelastic excitation of specific collective excitations of both nuclei, leading to a ...
G. R. Satchler, R. S. Mackintosh, S. Ohkubo, Y. Hirabayashi   +3 more
core   +2 more sources

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

TRPtracker: a community database for monitoring praziquantel sensitivity at TRPMPZQ variants

International Journal for Parasitology: Drugs and Drug Resistance
The anthelmintic praziquantel (PZQ) has been used for decades as the clinical therapy for schistosomiasis, and remains the only available drug. As a cheap and effective drug therapy for all human disease-causing Schistosoma species, usage of PZQ ...
Claudia M. Rohr, Sang-Kyu Park, Kelsilandia Aguiar-Martins, Timothy J.C. Anderson, Duncan J. Berger, Matthew Berriman, Sarah K. Buddenborg, Amaya L. Bustinduy, Frédéric D. Chevalier, James A. Cotton, Thomas Crellen, Stephen R. Doyle, Aidan M. Emery, Julien Kincaid Smith, Safari Kinung'hi, Poppy H.L. Lamberton, Winka Le Clec'h, Eric Ndombi, Tom Pennance, Candia Rowel, Shannan S. Summers, John Vianney Tushabe, Martin Walker, Bonnie L. Webster, Joanne P. Webster, Shona Wilson, Jonathan S. Marchant   +26 more
doaj   +1 more source

Insulin Increases Expression of TRPC6 Channels in Podocytes by a Calcineurin-Dependent Pathway

Cellular Physiology and Biochemistry, 2016
Background/Aims: Insulin signaling to podocytes is relevant for the function of the glomerulus. Now, we tested the hypothesis that insulin increases the surface expression of canonical transient receptor potential canonical type 6 (TRPC6) channels in ...
Shengqiang Xia, Ying Liu, Xinming Li, Florian Thilo, Martin Tepel   +4 more
doaj   +1 more source