Results 241 to 250 of about 11,137,717 (304)

Four‐Year Cognitive Outcomes in Multiple Sclerosis: Associations With Lesion Myelin Integrity

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Cognitive impairment is prevalent in patients with multiple sclerosis (MS) but whether lesion myelin integrity influences future cognitive outcomes remains unclear. We investigated the relationship between baseline lesion myelin water fraction (MWF) and cognitive performance 4 years later.
Iliana Pliska‐Bloch, Hannah Schwartz, Kimberly H. Markowitz, Abhishek Jaywant, Christopher D. Hildenbrand, Jai Perumal, Ulrike W. Kaunzner, Thanh D. Nguyen, Sandra Hurtado Rúa, Susan A. Gauthier   +9 more
wiley   +1 more source

Hydrostatically driven microfluidic sorting of highly motile sperm using multiple parallel microchannels via rheotaxis and thigmotaxis. [PDF]

Biomed Microdevices
Hyakutake T, Ikeno H, Takahashi R, Yasui M, Mita M, Yumoto S, Akiyama K, Tsukahara H, Shirasawa A.   +8 more
europepmc   +1 more source

Rheumatoid Arthritis and Coronary Artery Calcium Progression: A Case Cohort Analysis From ELSA‐Brasil

Arthritis Care &Research, EarlyView.
Objective To investigate the association between rheumatoid arthritis (RA) and coronary artery calcium (CAC) prevalence, incidence, and progression over four years in adults without prior cardiovascular disease. Methods A case‐cohort study within the Brazilian Longitudinal Study of Adult Health (ELSA‐Brasil) included 585 participants (86 patients with ...
Patrícia Fonseca Estrada, Marcos Rafael N. Cavalcante, Itamar de Souza Santos, Márcio S. Bittencourt, Vandrize Meneghini, Paulo A. Lotufo, Alessandra C. Goulart, Isabela M. Bensenor   +7 more
wiley   +1 more source

Advances in Multidimensional Molecular Mechanisms of Epilepsy and Precision Therapy Strategies. [PDF]

CNS Neurosci Ther
Han Y, Xu J, Shen Y, Zhang J, Li X, Yao X, Qi L, Sun H.   +7 more
europepmc   +1 more source

Real‐World Safety and Effectiveness of JAK Inhibitors in Systemic Sclerosis: A Propensity‐Matched Study From the EUSTAR Cohort

Arthritis Care &Research, EarlyView.
Objective JAK inhibitors (JAKi) have shown promising effects in early‐phase studies of systemic sclerosis (SSc). We aimed to assess the safety and explore the effectiveness of JAKi compared to conventional immunosuppressants in SSc. Methods A longitudinal retrospective study of the European Scleroderma Trials and Research Group (EUSTAR) cohort was ...
Stefano Di Donato, Marie‐Elise Truchetet, Marco Minerba, Oliver Distler, Juan José Alegre Sancho, Yolanda Braun‐Moscovici, Christina Bergmann, Petros Sfikakis, Jeska K. de Vries‐Bouwstra, Murray Baron, Silvia Bellando‐Randone, Lorenzo Dagna, Christopher P. Denton, Madelon C. Vonk, Vanessa Smith, Ivan Castellvi, Gabriela Riemekasten, Andra Balanescu, Masataka Kuwana, Maria De Santis, Kamal Solanki, Anastas Batalov, Vahan Mukuchyan, Marco Matucci‐Cerinic, Yannick Allanore, Francesco Del Galdo, Michael Hughes, EUSTAR Collaborators   +27 more
wiley   +1 more source

ENaC and Tight Junction Proteins: Coordinated Regulation of Alveolar Fluid Homeostasis in ALI/ARDS. [PDF]

Pharmaceuticals (Basel)
Li S, Wang J, Yin Z, Xin S, Nie H, Yu T.
europepmc   +1 more source

Efficacy of sodium channel blockers in treating myotonia is independent of action potential sodium current block. [PDF]

J Physiol
Walker P, Foy B, Wang X, Pham KM, Myers J, Dupont C, Kohli S, Deardorff AS, Voss AA, Rich MM.   +9 more
europepmc   +1 more source

Integrated machine learning and in vitro pipeline for TRPA1-active chemesthetic flavor compounds: From predictive screening to molecular mechanisms. [PDF]

Curr Res Food Sci
Wen X, Zhang Q, Wang S, Shi Q, Wang J, Fan W, Guan S, Chai G.   +7 more
europepmc   +1 more source

The Pesticide Pyrethroid Metabolite 3-Phenoxybenzoic Acid (3-PBA) Impairs Human Cardiac Na_v1.5 and Action Potential Depolarization. [PDF]

Cardiovasc Toxicol
de Lima Conceição MR, Marques LP, da Silva Alcantara F, de Morais RLT, Fogaça-Santos V, Orts DJB, Pesquero JB, de Souza DS, Roman-Campos D.   +8 more
europepmc   +1 more source