Results 271 to 280 of about 958,913 (319)

Suzetrigine: A promising analgesic targeting voltage-gated sodium channel.

Indian J Pharmacol
Dey S, Eeshwar MV, Chamala V, Gupta SK.
europepmc   +1 more source

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Channel potential and channel width in narrow buried-channel MOSFET's

IEEE Transactions on Electron Devices, 1984
A new method is described for determining the effective width over which incremental charge spreads in a narrow buried-channel transistor. The method is based on the transconductance in the buried-channel mode. Experimental results for effective widths and channel potential shifts are presented for MOSFET's with effective channel widths from 2 to 10 µm.
B.C. Burkey, G. Lubberts, E.A. Trabka, T.J. Tredwell   +3 more
openaire   +1 more source

Potential Proton‐Release Channels in Bacteriorhodopsin

ChemPhysChem, 2008
AbstractThe protein bacteriorhodopsin pumps protons across a bacterial membrane; its pumping cycle is triggered by the photoisomerization of a retinal cofactor and involves multiple proton‐transfer reactions between intermittent protonation sites. These transfers are either direct or mediated by hydrogen‐bonded networks, which may include internal ...
Alain, Chaumont, Marcel, Baer, Gerald, Mathias, Dominik, Marx   +3 more
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Potential Flow in Channels

SIAM Journal on Scientific and Statistical Computing, 1990
A method is presented for calculating potential flows in infinite channels. Given a collection of N sources in the channel and a zero normal flow boundary condition, the method requires an amount of work proportional to N to evaluate the induced velocity field at each source position.
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Ion channels and postsynaptic potentials

Biophysical Chemistry, 1988
Neurotransmitters open transmembrane ion channels in target membranes. At the motor endplate, the open time of channels activated by acetylcholine determines the time course of the endplate current. Endplate channels are selective for cations and their conductance and open times are influenced by the nature of the permeating cation.
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Coupled-channel potential for nucleons and deltas

Physical Review C, 1993
We propose a nucleon-nucleon potential for which the [ital NN], [ital N][Delta], and [Delta][Delta] channels are coupled by energy-independent, nonlocal interactions constructed from meson-exchange interactions. The same vertex couplings that were utilized in earlier studies based on the Bonn single-channel [ital NN] potential are adopted. We arrive at
, Haidenbauer, , Holinde, , Johnson
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Effect of channel geometry on the electrostatic potential in acetylcholine channels

Mathematical Biosciences, 2003
We study the effect of channel geometry on the potential barrier encountered by ions as they permeate the acetylcholine receptor channel. Among the various channel geometries which have been used to represent the acetylcholine receptor channel include the cylinder and the toroidal catenary.
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Transient Receptor Potential Channels and Mechanosensation

Annual Review of Neuroscience, 2013
Transient receptor potential (TRP) channels act as sensors for a range of stimuli as diverse as light, sound, touch, pheromones, and tissue damage. Their role in mechanosensation in the animal kingdom, identified by gene ablation studies, has raised questions about whether they are directly mechanically gated, whether they act alone or in concert with ...
Niels, Eijkelkamp, Kathryn, Quick, John N, Wood   +2 more
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TRP Channel Antagonists as Potential Antitussives

Lung, 2011
Cough is a troublesome symptom associated with many respiratory diseases. In some instances cough can become prolonged and excessive, and chronic cough of various aetiologies is a common presentation to specialist respiratory clinics. However, current treatment options are limited.
Megan S, Grace, Eric, Dubuis, Mark A, Birrell, Maria G, Belvisi   +3 more
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