Results 21 to 30 of about 2,601,570 (295)

Transient Receptor Potential Channels and Itch

open access: yesInternational Journal of Molecular Sciences, 2022
Transient Receptor Potential (TRP) channels are multifunctional sensory molecules that are abundant in the skin and are involved in the sensory pathways of itch, pain, and inflammation. In this review article, we explore the complex physiology of different TRP channels, their role in modulating itch sensation, and their contributions to the ...
Mahmoud, Omar   +2 more
openaire   +2 more sources

Particle transport across a channel via an oscillating potential [PDF]

open access: yes, 2017
Membrane protein transporters alternate their substrate-binding sites between the extracellular and cytosolic side of the membrane according to the alternating access mechanism.
Dagdug, Leonardo   +4 more
core   +2 more sources

TRP channels as potential drug targets [PDF]

open access: yesBiology of the Cell, 2004
Abstract Calcium (Ca2+) is an ubiquitous intracellular signal that is responsible for a plethora of cellular processes including fertilization, secretion, contraction, neuronal signaling and learning. In addition, changes in intracellular Ca2+ have been known to influence cell proliferation and differentiation for more than three decades.
Ulrich, Wissenbach   +2 more
openaire   +2 more sources

Classical Transient Receptor Potential 1 (TRPC1): Channel or Channel Regulator?

open access: yesCells, 2014
In contrast to other Classical Transient Receptor Potential TRPC channels the function of TRPC1 as an ion channel is a matter of debate, because it is often difficult to obtain substantial functional signals over background in response to over-expression
Alexander Dietrich   +2 more
doaj   +1 more source

Compressive sensing based Bayesian sparse channel estimation for OFDM communication systems: high performance and low complexity [PDF]

open access: yes, 2014
In orthogonal frequency division modulation (OFDM) communication systems, channel state information (CSI) is required at receiver due to the fact that frequency-selective fading channel leads to disgusting inter-symbol interference (ISI) over data ...
Adachi, Fumiyuki   +3 more
core   +4 more sources

Simulation and calculation of the contribution of hyperpolarization-activated cyclic nucleotide-gated channels to action potentials [PDF]

open access: yesArchives of Biological Sciences, 2016
The hyperpolarization-activated cyclic nucleotide-gated (HCN) channel, which mediates the influx of cations, has an important role in action potential generation.
Liao Liping   +6 more
doaj   +1 more source

Charge fluctuations and boundary conditions of biological ion channels:effect on the ionic transition rate [PDF]

open access: yes, 2009
A self-consistent solution is derived for the Poisson-Nernst-Planck (PNP) equation, valid both inside a biological ion channel and in the adjacent bulk fluid. An iterative procedure is used to match the two solutions together at the channel mouth. Charge
Eisenberg, R. S.   +3 more
core   +1 more source

A fast Markovian method for modeling channel noise in neurons

open access: yesHeliyon, 2023
Channel noise results from rapid transitions of protein channels from closed to open state and is generally considered as the most dominant source of electrical noise causing membrane-potential fluctuations even in the absence of synaptic inputs.
Norbert Ankri, Dominique Debanne
doaj   +1 more source

The Emerging Chondrocyte Channelome

open access: yesFrontiers in Physiology, 2010
Chondrocytes are the resident cells of articular cartilage and are responsible for synthesising a range of collagenous and non-collagenous extracellular matrix macromolecules.
Richard Barrett-Jolley   +3 more
doaj   +1 more source

Alterations of Electrophysiological Properties and Ion Channel Expression in Prefrontal Cortex of a Mouse Model of Schizophrenia

open access: yesFrontiers in Cellular Neuroscience, 2019
Maternal immune activation (MIA) and juvenile social isolation (SI) are two most prevalent and widely accepted environmental insults that could increase the propensity of psychiatric illnesses.
Zhen Mi   +6 more
doaj   +1 more source

Home - About - Disclaimer - Privacy