Results 21 to 30 of about 285,190 (188)

Myosin chaperones

open access: yesCurrent Opinion in Structural Biology, 2014
The folding and assembly of myosin motor proteins is essential for most movement processes at the cellular, but also at the organism level. Importantly, myosins, which represent a very diverse family of proteins, require the activity of general and specialized folding factors to develop their full motor function.
Hellerschmied, Doris, Clausen, Tim
openaire   +2 more sources

Extragenic Suppression analysis of TS mutations using Sec61p [PDF]

open access: yes, 2007
During synthesis, secretory and membrane proteins are cotranslationally translocated into the lumen of the endoplasmic reticulum through an aqueous gated channel.
Sterling Smith
core   +2 more sources

Chain-Selective Isotopic Labeling of the Heterodimeric Type III Secretion Chaperone, Scc4:Scc1, Reveals the Total Structural Rearrangement of the Chlamydia trachomatis Bi-Functional Protein, Scc4

open access: yesBiomolecules, 2020
Scc4 is an unusual bi-functional protein from Chlamydia trachomatis (CT) that functions as a type III secretion system (T3SS) chaperone and an RNA polymerase (RNAP)-binding protein.
Thilini O. Ukwaththage   +3 more
doaj   +1 more source

DnaK3 Is Involved in Biogenesis and/or Maintenance of Thylakoid Membrane Protein Complexes in the Cyanobacterium Synechocystis sp. PCC 6803

open access: yesLife, 2020
DnaK3, a highly conserved cyanobacterial chaperone of the Hsp70 family, binds to cyanobacterial thylakoid membranes, and an involvement of DnaK3 in the biogenesis of thylakoid membranes has been suggested. As shown here, light triggers synthesis of DnaK3
Adrien Thurotte   +4 more
doaj   +1 more source

Unraveling the molecular basis of subunit specificity in P pilus assembly by mass spectrometry [PDF]

open access: yes, 2008
P pili are multisubunit fibers essential for the attachment of uropathogenic Escherichia coli to the kidney. These fibers are formed by the noncovalent assembly of six different homologous subunit types in an array that is strictly defined in terms of ...
A. E. Ashcroft   +28 more
core   +2 more sources

Mechanistic Insight Into the Interaction Between Helicobacter pylori Urease Subunit α and Its Molecular Chaperone Hsp60

open access: yesFrontiers in Microbiology, 2019
Helicobacter pylori is the etiologic agent in a variety of gastroduodenal diseases. As its key pathogenic factors, both urease and Hsp60 play important roles in the pathogenesis of H. pylori.
Huilin Zhao   +9 more
doaj   +1 more source

Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Ubiquitylation as a Novel Pharmaceutical Target for Cystic Fibrosis

open access: yesPharmaceuticals, 2020
Mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene decrease the structural stability and function of the CFTR protein, resulting in cystic fibrosis. Recently, the effect of CFTR-targeting combination therapy has dramatically
Ryosuke Fukuda, Tsukasa Okiyoneda
doaj   +1 more source

Dynamic Activity of Histone H3-Specific Chaperone Complexes in Oncogenesis

open access: yesFrontiers in Oncology, 2022
Canonical histone H3.1 and variant H3.3 deposit at different sites of the chromatin via distinct histone chaperones. Histone H3.1 relies on chaperone CAF-1 to mediate replication-dependent nucleosome assembly during S-phase, while H3.3 variant is ...
Ting Wen, Qiao Yi Chen
doaj   +1 more source

The effect of maternal iron deficiency on zinc and copper levels and on genes of zinc and copper metabolism during pregnancy in the rat [PDF]

open access: yes, 2019
Fe deficiency is relatively common in pregnancy and has both short- and long-term consequences. However, little is known about the effect on the metabolism of other micronutrients.
Cottin, Sarah C.   +5 more
core   +5 more sources

Chaperone-assisted translocation [PDF]

open access: yesPhysical Biology, 2004
24 pages, 3 figures, LaTeX (IOP class file)
Ambjørnsson, T, Metzler, R
openaire   +3 more sources

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