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Quality control of traditional Chinese medicine Chelidonii herba based on 2D-Q-NMR. [PDF]

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The Pharmacokinetics of Chelerythrine Solution and Chelerythrine Liposomes after Oral Administration to Rats

Planta Medica, 2013
Chelerythrine is a quaternary benzo[c]phenanthridine alkaloid which has many potent pharmacological effects and can dissolve well in water; dihydrochelerythrine has recently been identified as a chelerythrine metabolite in rat. Most methods of preparation of liposomes suffer from the drawback of poor incorporation of water-soluble drugs.
Xiaofeng Niu, Weifeng Li
exaly   +3 more sources

Structural modification of sanguinarine and chelerythrine and their antibacterial activity

Natural Product Research, 2011
In this study, five derivatives of sanguinarine (1) and chelerythrine (2) were prepared, with 1 and 2 as starting materials, by reduction, oxidation and nucleophilic addition to the iminium bond C=N+. The structures of all compounds were elucidated on account of their MS, ¹H-NMR and ¹³C-NMR data.
Le Zhou
exaly   +3 more sources

Interaction of chelerythrine with inositol phosphate metabolism

Fundamental and Clinical Pharmacology, 2002
Chelerythrine, a potent inhibitor of protein kinase C (PKC), was evaluated for its effect on inositol phosphate (IP) metabolism in newborn rat cardiomyocytes in culture. In a first step, we evaluated the effect of chelerythrine on IP accumulation in basal conditions.
Philippe le Corvoisier
exaly   +3 more sources

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