Proteomic identification of PKC-mediated expression of 20E-induced protein in Drosophila melanogaster [PDF]
, 2007 Ecdysone receptor (EcR) and its heterodimeric partner, ultraspiracle protein (USP), are nuclear receptors that mediate the action of the insect molting hormone 20-hydroxyecdysone (20E). There is evidence that the activity of both receptors is affected by
An, Shiheng +4 more
core +1 more source
Proteomic Insights into the Antimicrobial Mechanism of Chelerythrine Against Methicillin-Resistant
Natural Product CommunicationsBackground Methicillin-resistant Staphylococcus aureus (MRSA) is a major global health threat, causing infections that are difficult to treat due to resistance to standard antibiotics.
Jianhua Liao +4 more
doaj +1 more source
Come-back of phenanthridine and phenanthridinium derivatives in 21st century [PDF]
, 2014 Phenanthridine derivatives are one of the most intensively studied families of biologically active compounds with efficient DNA binding ; attracting attention about time of DNA structure discovery (1960ies), early recognized as a symbol of DNA ...
Piantanida, Ivo +2 more
core +2 more sources
TDP-43 self-interaction is modulated by redox-active compounds Auranofin, Chelerythrine and Riluzole
Scientific Reports, 2018 Amyotrophic lateral sclerosis (ALS) represents a fatal neurodegenerative disease, which is characterized by a rapid loss of lower and upper motor neurons.
Moritz C. Oberstadt +7 more
semanticscholar +1 more source
Differential regulation of endothelium behavior by progesterone and medroxyprogesterone acetate [PDF]
, 2013 Medroxyprogesterone acetate (MPA) is a synthetic progestin commonly used in hormone replacement therapy (HRT). The aim of this work was to study and compare the effect of progesterone (Pg) and MPA, on the regulation of cellular events associated with ...
Campelo, Adrián Esteban +2 more
core +2 more sources
Chelerythrine induced cell death through ROS-dependent ER stress in human prostate cancer cells
OncoTargets and Therapy, 2018 Introduction Prostate cancer is the most common noncutaneous cancer and the second leading cause of cancer-related mortality worldwide and the third in USA in 2017.
Songjiang Wu +7 more
semanticscholar +1 more source
Metabolomics analysis of the effects of chelerythrine on Ustilaginoidea virens.
Journal of pesticide scienceRice false smut (RFS) caused by Ustilaginoidea virens is widely distributed in major rice-producing regions. Previous studies have shown that treating RFS with chelerythrine can decrease the germination of fungus spores by 86.7% and induce fungal cell apoptosis. In the present study, the effects of chelerythrine on the metabolism of U.
Wei, Qinghui +8 more
openaire +2 more sources
Kidney & Blood Pressure Research, 2017 Background/Aims: Chelerythrine (CHE), a benzophenanthridine alkaloid, is a potent, selective, and cell-permeable protein kinase C (PKC) inhibitor. The purpose of the present study was to evaluate the effect of CHE on myocardial recovery after renal ...
Bo Hu +7 more
semanticscholar +1 more source
Alkaloids Induce Programmed Cell Death in Bloodstream Forms of Trypanosomes (Trypanosoma b. brucei)
Molecules, 2008 The potential induction of a programmed cell death (PCD) in Trypanosoma b. brucei by 55 alkaloids of the quinoline, quinolizidine, isoquinoline, indole, terpene, tropane, steroid, and piperidine type was studied by measuring DNA fragmentation and changes
Michael Wink, Vera Rosenkranz
doaj +1 more source
Purinergic P2 receptors trigger adenosine release leading to adenosine A2A receptor activation and facilitation of long-term potentiation in rat hippocampal slices [PDF]
, 2003 Electrophysiological recordings were used to investigate the effects of ATP analogues on [theta]-burst-induced long-term potentiation (LTP) in rat hippocampal slices.
Almeida, T. +4 more
core +1 more source