Results 71 to 80 of about 468,477 (308)
Pathogens, 2021 Nephropathia Epidemica (NE), endemic to several Volga regions of Russia, including the Republic of Tatarstan (RT) and the Republic of Mordovia (RM), is a mild form of hemorrhagic fever with renal syndrome caused by infection with rodent-borne ...
Ekaterina Martynova +16 more
doaj +1 more source
Chemokines, Chemokine Receptors and Atherosclerosis
, 2005 Publisher Summary This chapter focuses on chemokines, chemokine receptors, and atherosclerosis. Chemokines play essential roles in inflammation and disease. This family of inflammatory mediators has diverse roles in both immune and inflammatory responses, including the regulation of cellular recruitment, activation, and differentiation.
John, A, Channon, K, Greaves, D
openaire +2 more sources
Biomedical Papers, 2000 Chemokines mediate their multiple effects by binding to a variety of specific receptors, that comprise a subfamily of rhodopsin-like, 7-transmembrane domain receptors, coupled to G proteins. Some of these receptors serve as coreceptors for HIV, some of them could be expressed as markers for T lymphocyte functional differentiation.
openaire +2 more sources
FEBS Open Bio, EarlyView.Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda +12 more
wiley +1 more source
Effective Treatments for Bladder Cancer Affecting CXCL9/CXCL10/CXCL11/ CXCR3 Axis: A Review
Oman Medical Journal, 2020 Bladder cancer (BC) originates mainly from the epithelial compartment of the bladder, which is defined as transitional cell carcinoma or urothelial cell carcinoma. About 70% of patients with BC will survive five years from diagnosis.
Alireza Nazari +6 more
doaj +1 more source
Beneficial Immunomodulatory Effects of Fluticasone Propionate in Chlamydia pneumoniae-Infected Mice
Pathogens, 2021 The associations between inhaled corticosteroid (ICS) use and pulmonary infections remains controversial. Chlamydia pneumoniae (C. pneumoniae) accounts for asthma exacerbations; however, there are no data regarding ICS effects on C. pneumoniae infections.
Dóra Paróczai +5 more
doaj +1 more source
Mathematical Model of HIV superinfection dynamics and R5 to X4 switch [PDF]
, 2006 During the HIV infection several quasispecies of the virus arise, which are able to use different coreceptors, in particular the CCR5 and CXCR4 coreceptors (R5 and X4 phenotypes, respectively).
Bagnoli, Franco +2 more
core +1 more source
FEBS Open Bio, EarlyView.We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa +2 more
wiley +1 more source
Sulforaphane ameliorates non-alcoholic steatohepatitis by KLF4-mediated macrophage M2 polarization
Food Science and Human WellnessNon-alcoholic fatty liver disease (NAFLD) has become a global issue and a severe threat to public health. However, to date, no approved therapeutic drugs have been developed.
Xianghui Huang +10 more
doaj +1 more source
Chimeric Oncolytic Adenovirus Armed Chemokine Rantes for Treatment of Breast Cancer
Bioengineering, 2022 The immunosuppressive state in the tumor microenvironment (TME) of breast cancer makes it difficult to treat with immunotherapy. Oncolytic viruses not only lyse tumor cells but also reshape the TME.
Lin Ang +8 more
doaj +1 more source