Results 161 to 170 of about 49,192 (255)
Cancer Medicine, Volume 15, Issue 5, May 2026.ABSTRACT Ovarian Cancer (OC), the deadliest gynecological malignancy, poses a major therapeutic challenge in advanced stages owing to its high recurrence rate and metastatic potential. In this regard, it is noteworthy that immunotherapy has recently gained significant attention in OC treatment, a phenomenon attributable to notable advances in over‐the ...
Liying Wang +4 more
wiley +1 more source
The CXCL12/CXCR4 Axis: An Emerging Therapeutic Target for Chronic Pain
Journal of Pain ResearchZhangwei Chen, Yunfan Xia, Boyi Liu, Jianqiao Fang, Qimiao Hu The Third School of Clinical Medicine (School of Rehabilitation Medicine), Zhejiang Chinese Medical University, Hangzhou, People’s Republic of ChinaCorrespondence: Qimiao Hu, The Third School ...
Chen Z, Xia Y, Liu B, Fang J, Hu Q
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Health Science Reports, Volume 9, Issue 5, May 2026.ABSTRACT Background and Aim Janus kinases/signal transducers and activators of transcription (JAK/STAT) pathway is crucial for various stages of immunity, from innate to adaptive responses. Type 1 IFNs activate JAK/STAT pathway by binding to receptors on JAK, phosphorylating STAT and upregulating interferon‐stimulated genes (ISGs) leading to cytokines ...
Esimebia Adjovi Amegashie +7 more
wiley +1 more source
Characterization and Validation of Antibodies for Immunohistochemical Staining of the Chemokine CXCL12. [PDF]
J Histochem Cytochem, 2019 Fricker SP +6 more
europepmc +1 more source
Chronic Pain: Epidemiology, Pathophysiology, and Clinical Management
MedComm, Volume 7, Issue 5, May 2026.The multidimensional nature of chronic pain is illustrated through four interconnected domains. (Left) Epidemiology and Global Burden: Chronic pain affects approximately one in five individuals globally, contributing to a rising trend in disability‐adjusted life years (YLDs) and a significant socioeconomic impact.
Zhihao Shang +12 more
wiley +1 more source
Ccl5 establishes an autocrine high-grade glioma growth regulatory circuit critical for mesenchymal glioblastoma survival [PDF]
, 2017 Gutmann, David H +4 more
core +2 more sources
Medicinal Research Reviews, Volume 46, Issue 3, Page 672-712, May 2026.ABSTRACT Respiratory syncytial virus (RSV) is a common virus that causes respiratory infections, posing a serious threat, particularly to infants, the elderly, and individuals with compromised immune systems. As the leading cause of lower respiratory tract infections (LRTIs) in infants, RSV is responsible for millions of cases worldwide each year.
Jie Shi +6 more
wiley +1 more source
Oral Science International, Volume 23, Issue 2, May 2026.ABSTRACT Objective Tissue inhibitor of metalloproteinase‐1 (TIMP1) is a secreted glycoprotein that controls matrix metalloproteinase activity and exerts pleiotropic signaling functions. We investigated the clinical relevance of TIMP1 in head and neck squamous cell carcinoma (HNSCC; TCGA‐HNSC), focusing on survival, immunologic contexture, pathway ...
Aiko Kurosaka +2 more
wiley +1 more source
Veterinary Record Case Reports, Volume 14, Issue 2, May 2026.Abstract A 6‐year‐old, spayed, female labrador retriever was presented with left distal radial swelling. Imaging, cytology and biopsy identified an aggressive radial lesion with metastasis to the left axillary lymph node, and a diagnosis of presumptive osteosarcoma was made.
Veronica Perez‐Rodriguez +4 more
wiley +1 more source