Results 171 to 180 of about 97,684 (248)

Selected Chemokines as Prognostic Biomarkers and Therapeutic Targets in Ovarian Cancer. [PDF]

Curr Issues Mol Biol
Długaszek A, Kabut J, Domagała-Haduch M, Gorzelak-Magiera A, Sadurska J, Morawiec ML, Mielczarek-Palacz A, Gisterek-Grocholska I.   +7 more
europepmc   +1 more source

Mitochondrial transfer in acute myeloid leukaemia and multiple myeloma: Mechanisms, consequences and potential therapeutic opportunities

The FEBS Journal, Volume 293, Issue 17, Page 5107-5120, September 2026.
Mitochondria can be transferred from bone marrow cells to cancer cells in acute myeloid leukaemia and multiple myeloma, boosting tumour energy production, growth, and drug resistance. This review highlights key transfer mechanisms and shows how targeting mitochondrial movement and dynamics may offer new therapeutic strategies to limit cancer ...
Ebubechukwu Nwarunma, Mark T. S. Williams   +1 more
wiley   +1 more source

Comprehensive In Silico Analysis of the CXCL12, C55Y Mutation Reveals Structural and Functional Disruption in CXCR4/CXCR7 Signaling. [PDF]

Evol Bioinform Online
Kamal S, Ullah N, Wang Y, Qin C, He R, Ullah H, Ahmed Mujtaba M, Amanullah A, Khan KA, Amjad Kamal M, Li W.   +10 more
europepmc   +1 more source

Essential role of immobilized chemokine CXCL12 in the regulation of the humoral immune response. [PDF]

Proc Natl Acad Sci U S A, 2017
Barinov A, Luo L, Gasse P, Meas-Yedid V, Donnadieu E, Arenzana-Seisdedos F, Vieira P.   +6 more
europepmc   +1 more source

Germinal Center Selection and Plasma Cell Differentiation

Immunological Reviews, Volume 342, Issue 1, September 2026.
ABSTRACT Germinal centers (GCs) are specialized microenvironments in which B cells undergo affinity maturation through iterative cycles of somatic hypermutation, proliferation and selection, generating antibodies with improved antigen‐binding properties.
Adrien Sprumont, Oliver Bannard
wiley   +1 more source

Attract to kill: Exploring the potential of motility trapping as a novel treatment strategy for high-grade gliomas. [PDF]

Neuro Oncol
Bamelis AS, Metselaar DS, Sie M, Lootens T, Willems L, Raedt R, Vandersteene J.   +6 more
europepmc   +1 more source

Plasma Cell Selection and Migration in the Establishment of Long‐Lived Antibody Responses

Immunological Reviews, Volume 342, Issue 1, September 2026.
ABSTRACT As B cells are activated and differentiate into plasma cells, they execute migration programs that allow them to traffic within secondary lymphoid tissues and reach the bone marrow, where they can mature as long‐lived plasma cells. Recent studies have revealed mechanisms underlying not only affinity‐driven but also isotype‐driven plasma cell ...
Wataru Ise, Kazuhiro Suzuki, Tomohiro Kurosaki   +2 more
wiley   +1 more source

<i>CXCL12</i> Expression and Clinicopathological Features at the Invasive Front of Pancreatic Cancer. [PDF]

Clin Med Insights Oncol
Imamura S, Uehara T, Iwaya M, Asaka S, Sugenoya S, Sawaguchi H, Yoshizawa T, Kuraishi Y, Nakajima T, Komamura S, Nakamura A, Iwaya Y, Shimizu A, Soejima Y, Ota H, Nagaya T.   +15 more
europepmc   +1 more source

Patient‐Derived iPSC‐MSC Modelling Reveals Reversible GSK3‐Mediated Suppression of Mesenchymal Lineage Differentiation in Legg‐Calvé‐Perthes Disease

Journal of Cellular and Molecular Medicine, Volume 30, Issue 17, September 2026.
ABSTRACT Legg‐Calvé‐Perthes disease (LCPD) is an idiopathic paediatric osteonecrosis characterized by avascular injury to the femoral head, resulting in structural collapse and early osteoarthritis. Although mesenchymal stem cell (MSC) dysfunction has been implicated, the underlying mechanisms remain unclear due to the absence of human disease models ...
Binna Seol, Hyung Jin Lim, Cho Lok Song, Jungwoon Lee, Yee Sook Cho   +4 more
wiley   +1 more source

The chemokine network in triple-negative breast cancer: its role in immune microenvironment regulation, and prospects for targeted therapy. [PDF]

Front Immunol
Wang W, Chen L, Guo W, Hu M, Han X, Xia X, Xu W, Ma W.   +7 more
europepmc   +1 more source