Results 151 to 160 of about 33,556 (238)

Dual blockade of the pro-inflammatory chemokine CCL2 and the homeostatic chemokine CXCL12 is as effective as high dose cyclophosphamide in murine proliferative lupus nephritis

, 2016
Induction therapy of proliferative lupus nephritis still requires the use of unselective immunosuppressive drugs with significant toxicities. In search of more specific drugs with equal efficacy but fewer side effects we considered blocking pro ...
Rupanagudi, Khader Valli, Anders, Hans-Joachim, Kulkarni, Onkar P, Kumar, Santhosh VR, Eulberg, Dirk, Devarapu, Satish Kumar, Klussmann, Sven   +6 more
core   +1 more source

Advances in Gastric Cancer Research: Insights Into Carcinogenesis, the Tumor Microenvironment, Metastasis, and Factors Influencing Prognosis

Annals of Gastroenterological Surgery, Volume 10, Issue 4, Page 984-994, July 2026.
ABSTRACT Background The Department of Gastroenterological Surgery at Kumamoto University has maintained a commitment to integrating cutting‐edge clinical practice with fundamental research, particularly concerning malignant diseases of the digestive tract.
Hideo Baba, Takatsugu Ishimoto, Yoshifumi Baba, Hiromitsu Hayashi, Masaaki Iwatsuki   +4 more
wiley   +1 more source

The Role of the Chemokine CXCL12 on the Pathogenesis of Several Diseases

Bakirkoy Tip Dergisi / Medical Journal of Bakirkoy, 2022
Ekin Ece Gürer, Hayriye Şentürk Çiftçi, Süleyman Rüştü Oğuz, Demet Kıvanç, Sevgi Kalayoğlu Beşışık   +4 more
openaire   +1 more source

Salivary Extracellular Vesicles: Paradigm Shift in Liquid Biopsy Diagnostics

Journal of Extracellular Biology, Volume 5, Issue 7, July 2026.
ABSTRACT Extracellular vesicles (EVs), lipid bilayer nanoparticles released by virtually all cells, serve as essential messengers for intercellular communication. Due to their involvement in several pathophysiological processes, EVs have recently gained considerable attention as potentially diagnostic and prognostic biomarkers for various illnesses ...
Kwanele Xulu, Usri H. Ibrahim, Irene Mackraj, Carola Niesler   +3 more
wiley   +1 more source

Cancer Heterogeneity and Cancer Cell Plasticity: Molecular Mechanisms and Precision Therapy

MedComm, Volume 7, Issue 7, July 2026.
Tumor progression is driven by heterogeneity occurring across multiple biological scales. At the molecular level, tumor cells exhibit alterations across distinct omics layers, including genomic mutations, epigenomic reprogramming, transcriptional changes, and proteomic remodeling, collectively shaping tumor cell phenotypes and functional states.
Hanwen Hu, Zhixing Hao, Lili Li, Huiying Liu, Chenghui Yang, Zhen Wang   +5 more
wiley   +1 more source

Erratum: Gascon S.; et al. Characterization and Mathematical Modeling of Alginate/Chitosan-Based Nanoparticles Releasing the Chemokine CXCL12 to Attract Glioblastoma Cells. Pharmaceutics 2020, 12, 356. [PDF]

Pharmaceutics, 2020
Gascon S, Giraldo Solano A, El Kheir W, Therriault H, Berthelin P, Cattier B, Marcos B, Virgilio N, Paquette B, Faucheux N, Lauzon MA.   +10 more
europepmc   +1 more source

CXCL12-CXCR4 chemokine signaling is essential for NK-cell development in adult mice

, 2011
Natural killer (NK) cells are granular lymphocytes that are generated from hematopoietic stem cells and play vital roles in the innate immune response against tumors and viral infection.
Mamiko Noda, Tatsuki Sugiyama, Shinya Oishi, Nobutaka Fujii, Takashi Nagasawa, Yoshiki Omatsu   +5 more
core   +1 more source

The Role of CXCL12-CXCR4 Signaling Pathway in Pancreatic Development

Theranostics, 2013
Chemokine (C-X-C motif) receptor 4 (CXCR4) is the receptor for chemokine (C-X-C motif) ligand 12 (CXCL12, also known as stromal derived factor-1, Sdf1).
Keiichi Katsumoto, Shoen Kume
doaj  

Plasma Protein Analysis for Biomarker Discovery in Lung Cancer Treated With Atezolizumab Combination Therapy in J‐TAIL‐2

Cancer Science, Volume 117, Issue 7, Page 1948-1960, July 2026.
BLURB FOR ETOC: The J‐TAIL‐2 study (NCT04501497) evaluated the efficacy and safety of atezolizumab, an anti‐programmed death‐ligand 1, plus chemotherapy in patients with non‐small cell lung cancer (NSCLC) and extensive‐stage small cell lung cancer (ES‐SCLC) in real‐world settings.
Yasushi Goto, Makoto Nishio, Kadoaki Ohashi, Atsushi Osoegawa, Eiki Kikuchi, Hideharu Kimura, Junichi Shimizu, Eisaku Miyauchi, Hiroshige Yoshioka, Ichiro Yoshino, Toshihiro Misumi, Yasutaka Watanabe, Nobuyuki Katakami, Akira Kisohara, Masafumi Yamaguchi, Hirotaka Kuroki, Masamichi Sugimoto, Hisao Ashimura, Misa Tanaka, Akihiko Gemma   +19 more
wiley   +1 more source

[IL-17A activates mouse lung fibroblasts through promoting chemokine CXCL12 secretion]. [PDF]

Zhejiang Da Xue Xue Bao Yi Xue Ban, 2020
Wang H, Lyu J, Chen L, Yu W.
europepmc   +1 more source