Results 1 to 10 of about 455,922 (328)
Antimicrobial Chemokines [PDF]
Frontiers in Immunology, 2012 Chemokines are best known for their classic leukocyte chemotactic activity, which is critical for directing the immune response to sites of infection and injury.
Sunny C Yung, Philip M Murphy
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Cells, 2021 Although G protein-coupled receptor kinases (GRKs) have long been known to regulate G protein-coupled receptor (GPCR) desensitization, their more recently characterized functions as scaffolds and signalling adapters underscore that this small family of ...
Marta Laganà +2 more
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Microbiota, a key player in alcoholic liver disease [PDF]
Clinical and Molecular Hepatology, 2018 Alcoholic liver disease (ALD) is a major cause of morbidity and mortality worldwide. Only 20% of heavy alcohol consumers develop alcoholic liver cirrhosis.
Anne-Marie Cassard, Dragos Ciocan
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Specific microbiome profile in Takayasu’s arteritis and giant cell arteritis
Scientific Reports, 2021 Recent studies have provided evidence of a close link between specific microbiota and inflammatory disorders. While the vessel wall microbiota has been recently described in large vessel vasculitis (LVV) and controls, the blood microbiome in these ...
Anne Claire Desbois +4 more
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Efficient Plasma Cell Differentiation and Trafficking Require Cxcr4 Desensitization
Cell Reports, 2016 CXCR4 plays a central role in B cell immune response, notably by promoting plasma cell (PC) migration and maintenance in the bone marrow (BM). Gain-of-function mutations in CXCR4 affecting receptor desensitization have been reported in the rare ...
Vincent Biajoux +9 more
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Frontiers in Endocrinology, 2015 Although G protein-coupled receptor (GPCR) internalization has long been considered a major aspect of the desensitization process that tunes ligand responsiveness, internalization is also involved in receptor resensitization and signaling, as well as the
Angélique eLEVOYE +16 more
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Transplantation of human microbiota into conventional mice durably reshapes the gut microbiota
Scientific Reports, 2018 Human microbiota-associated (HMA) mice are an important model to study the relationship between liver diseases and intestinal microbiota. We describe a new method to humanize conventional mice based on bowel cleansing with polyethylene glycol followed by
Laura Wrzosek +9 more
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Chemokine Heterocomplexes and Cancer: A Novel Chapter to Be Written in Tumor Immunity
Frontiers in Immunology, 2018 Infiltrating immune cells are a key component of the tumor microenvironment and play central roles in dictating tumor fate, either promoting anti-tumor immune responses, or sustaining tumor growth, angiogenesis and metastasis.
Gianluca D'Agostino +3 more
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Inflammatory Chemokines in Atherosclerosis
Cells, 2021 Atherosclerosis is a long-term, chronic inflammatory disease of the vessel wall leading to the formation of occlusive or rupture-prone lesions in large arteries. Complications of atherosclerosis can become severe and lead to cardiovascular diseases (CVD)
Selin Gencer +4 more
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The Roles of Stroma-Derived Chemokine in Different Stages of Cancer Metastases
Frontiers in Immunology, 2020 The intricate interplay between malignant cells and host cellular and non-cellular components play crucial role in different stages of tumor development, progression, and metastases.
Shahid Hussain +8 more
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