Results 11 to 20 of about 18,475 (201)

The Chemokines CXC, CC and C in the Pathogenesis of COVID-19 Disease and as Surrogates of Vaccine-Induced Innate and Adaptive Protective Responses [PDF]

open access: yesVaccines, 2022
COVID-19 is one of the progressive viral pandemics that originated from East Asia. COVID-19 or SARS-CoV-2 has been shown to be associated with a chain of physio-pathological mechanisms that are basically immunological in nature.
Mojgan Noroozi Karimabad   +9 more
doaj   +2 more sources

Prognostic Biomarkers and Immunotherapeutic Targets Among CXC Chemokines in Pancreatic Adenocarcinoma

open access: yesFrontiers in Oncology, 2021
BackgroundPancreatic cancer is one of the principal causes of tumor-related death worldwide. CXC chemokines, a subfamily of functional chemotactic peptides, affect the initiation of tumor cells and clinical outcomes in several human malignant tumors ...
Dalong Wan   +2 more
exaly   +3 more sources

The Role of CXC Chemokines in Cardiovascular Diseases

open access: yesFrontiers in Pharmacology, 2022
Cardiovascular disease (CVD) is a class of diseases with high disability and mortality rates. In the elderly population, the incidence of cardiovascular disease is increasing annually.
Xiyi Lu   +12 more
doaj   +3 more sources

CXC Chemokine/Receptor Axis Profile and Metastasis in Prostate Cancer

open access: yesFrontiers in Molecular Biosciences, 2020
In this study, the effects of the CXC chemokine/receptor axis on lymph node and distant metastases of prostate cancer (PC) were analyzed. Further, mRNA expression data of metastatic PC were extracted from the Stand Up To Cancer–Prostate Cancer Foundation
Isaac Kim, Shigeo HORIE, Naoya Nagaya
exaly   +3 more sources

CXC chemokines in angiogenesis [PDF]

open access: yesCytokine & Growth Factor Reviews, 2005
CXC chemokines display pleiotropic effects in immunity, regulating angiogenesis, and mediating organ-specific metastases of cancer. In the context of angiogenesis, CXC chemokines are a unique family of cytokines, known for their ability to behave in a disparate manner in the regulation of angiogenesis.
Robert M, Strieter   +4 more
openaire   +3 more sources

Prognostic Significance and Immune Cell Infiltration Analysis of CXC Chemokines in Glioblastoma

open access: yesZhongliu Fangzhi Yanjiu, 2021
Objective To analyze the expression of CXC chemokines in glioblastoma (GBM), and investigate their prognostic value and potential roles as therapeutic targets. Methods Differential expression and prognostic value of CXC chemokines in GBM were obtained in
LIU Fangyuan, SU Xiulan
doaj   +1 more source

Pathophysiological impact of CXC and CX3CL1 chemokines in preeclampsia and gestational diabetes mellitus

open access: yesFrontiers in Cell and Developmental Biology, 2023
Diabetes-related pathophysiological alterations and various female reproductive difficulties were common in pregnant women with gestational diabetes mellitus (GDM), who had 21.1 million live births.
Amin Ullah   +4 more
doaj   +1 more source

Comprehensive analysis of prognostic value and immune infiltration of CXC chemokines in pancreatic cancer

open access: yesBMC Medical Genomics, 2022
Background The prognosis of pancreatic cancer is poor, with a 5-year survival rate of less than 10%. Studies have shown that chemokines in the tumour microenvironment are often altered, which is associated with immune infiltration and the prognosis and ...
Yanhua Jing   +3 more
doaj   +1 more source

Analysis of therapeutic targets and prognostic biomarkers of CXC chemokines in cervical cancer microenvironment

open access: yesCancer Cell International, 2021
Background The tumor microenvironment (TME) has received an increasing amount of attention. CXC chemokines can regulate immune cell transport and tumor cell activity to exert anti-tumor immunity.
Weina Kong   +7 more
doaj   +1 more source

Lipocalin‐2 activates hepatic stellate cells and promotes nonalcoholic steatohepatitis in high‐fat diet–fed Ob/Ob mice

open access: yesHepatology, EarlyView., 2022
Graphical summary of obesity‐induced NASH progression by LCN2 targeted to HSC activation. Abstract Background and Aims In obesity and type 2 diabetes mellitus, leptin promotes insulin resistance and contributes to the progression of NASH via activation of hepatic stellate cells (HSCs).
Kyung Eun Kim   +12 more
wiley   +1 more source

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