Results 101 to 110 of about 68,540 (230)

CC and CXC chemokines are pivotal mediators of cerebral injury in ischaemic stroke

, 2011
The definition of ischaemic stroke has been recently updated as an acute episode of neurological dysfunction caused by focal brain, spinal cord, or retinal ischaemia in the presence of a cerebral infarction. This "tissular" definition has highlighted the
DALLEGRI, FRANCO, QUERCIOLI, ALESSANDRA MARIA, BRAUNERSREUTHER V, VIVIANI, GIORGIO LUCIANO, MACH F, VENESELLI, EDVIGE MARIA, MIRABELLI BADENIER M, MONTECUCCO, FABRIZIO, Edvige Veneselli, Fabrizio Montecucco, Marisol Mirabelli-Badenier, François Mach, Vincent Braunersreuther, Giorgio Luciano Viviani, Franco Dallegri, Alessandra Quercioli   +15 more
core   +1 more source

Neuropsychiatric symptom improvement and biomarker changes with electroacupuncture in adolescent and young adult cancer survivors: A randomized pilot trial

Pediatric, Adolescent &Young Adult Cancer, Volume 1, Issue 1, November 2026.
Abstract Introduction Electroacupuncture (EA) shows promise for managing neuropsychiatric symptoms, yet its role in adolescents and young adults (AYAs) living with cancer remains unclear. This is a randomized, controlled, patient‐blinded and assessor‐blinded pilot trial comparing two EA regimens to evaluate the improvement of neuropsychiatric symptoms ...
Alexandre Chan, Matthew Heshmatipour, Ding Quan Ng, Julia Trudeau, Munjal M. Acharya, Anshu Agrawal, Shaista Malik, Lifang Xie, Yae Chang, Keri Zabokrtsky, Christine Yun, Carol Lin, Sonia Morales, Jamie Frediani, Lilibeth Torno   +14 more
wiley   +1 more source

Corneal and Conjunctival Fibroblasts Are Major Sources of Eosinophil-Recruiting Chemokines

Allergology International, 2009
Background: Differential expression of chemokine genes were investigated in various types of ocular surface cells. Methods: Primary cultures of human corneal epithelial cells (n = 3), corneal fibroblasts (n = 2), conjunctival epithelial cells (n = 2) and
Kazumi Fukagawa, Naoko Okada, Hiroshi Fujishima, Toshiharu Nakajima, Yoji Takano, Mari Tanaka, Murat Dogru, Yoshiyuki Satake, Kazuo Tsubota, Hirohisa Saito   +9 more
doaj   +1 more source

Anti-mycobacterial treatment reduces high plasma levels of CXC-chemokines detected in active tuberculosis by cytometric bead array [PDF]

, 2010
Chemokines recruit and activate leukocytes, assisting granuloma formation. Herein, we evaluated plasma chemokines in patients with active tuberculosis (ATB) and after completing treatment (TTB) and compared them to BCG-vaccinated healthy controls (HC ...
Abramo, Clarice, Alves, Caio César de Souza, Teixeira, Henrique Couto, Almeida, Caroline de Souza, Ferreira, Ana Paula, Mazzoccoli, Luciano   +5 more
core  

Expression of CC and CXC chemokines and chemokine receptors in human leprosy skin lesions.

, 2003
We have investigated the expression of chemokines and their receptors in leprosy skin lesions using immunohistochemistry. Skin biopsies from 25 leprosy patients across the leprosy spectrum, 11 patients undergoing type I reversal reactions and four normal
D N J LOCKWOOD, Lockwood, DNJ, Musonda, AC, A A KIRKALDY, Kirkaldy, AA, S SUNEETHA, A C MUSONDA, Suneetha, S, S KHANOLKHAR-YOUNG, Khanolkhar-Young, S   +9 more
core   +1 more source

A Blood‐Derived Factor Rescues ALS: Platelet Factor 4 Activates OPTN‐Dependent Autophagy to Clear SOD1 Aggregates Independently of PINK1

Advanced Science, Volume 13, Issue 58, 19 October 2026.
Systemic platelet factor 4 (PF4) is significantly depleted in amyotrophic lateral sclerosis (ALS). Peripheral PF4 replenishment restores central proteostasis by driving OPTN‐dependent, PINK1‐independent selective autophagy in motor neurons. This intervention effectively clears toxic SOD1 aggregates, blunts glial activation, and preserves neuromuscular ...
Qingjian Xie, Yanbo Zhu, Wenhua Jiang, Haobo Xie, Yaojia Li, Mengjie Hu, Kezheng Li, Huan Yu, Yixuan Pan, Chaoyi Jiang, Xueqin Song, Dongsheng Fan, Binbin Deng   +12 more
wiley   +1 more source

Breast tumor cell soluble factors induce monocytes to produce angiogenic but not angiostatic CXC chemokines

, 2005
Tumor cells are known to interact closely with nontumoral infiltrating cells in order to grow and proliferate. Monocyte-derived cells constitute a major component of the tumoral infiltrate and a high level of these cells has been associated with ...
Eliaou, J. F., Frédéric Toulza, Jean-François Eliaou, Pinet, V., Toulza, F., Valérie Pinet   +5 more
core   +1 more source

Fisetin Attenuates Human Macrophage Polarization and Pro‐Inflammatory Responses via NLRP3 and NF‐κB/MAPK Suppression

Cell Biology International, Volume 50, Issue 10, October 2026.
ABSTRACT Natural compounds with anti‐inflammatory properties are increasingly explored as therapeutic agents due to their lower risk of side effects compared with conventional drugs. Fisetin, a dietary bioflavonol abundant in fruits and vegetables, exhibits anti‐inflammatory activity in several cell types, including murine macrophages.
Nattaya Onpan, Chanchao Lorthongpanich, Pakpoom Kheolamai, Pimjai Chingsuwanrote, Napachai Rodboon, Sudjit Luanpitpong, Chonticha Saisawang, Surapol Issaragrisil   +7 more
wiley   +1 more source

Transcriptomal signatures of vaccine adjuvants and accessory immunostimulation of sentinel cells by toll-like receptor 2/6 agonists

Human Vaccines & Immunotherapeutics, 2018
An important component of vaccine development is the identification of safe and effective adjuvants. We sought to identify transcriptomal signatures of innate immune stimulating molecules using next-generation RNA sequencing with the goal of being able ...
Alex C. D. Salyer, Sunil A. David
doaj   +1 more source

Genomic organization, annotation, and ligand-receptor inferences of chicken chemokines and chemokine receptor genes based on comparative genomics

BMC Genomics, 2005
Background Chemokines and their receptors play important roles in host defense, organogenesis, hematopoiesis, and neuronal communication. Forty-two chemokines and 19 cognate receptors have been found in the human genome.
Sze Sing-Hoi, Yilmaz Ahmet, Adelson David L, Wang Jixin, Jin Yuan, Zhu James J   +5 more
doaj   +1 more source