Results 11 to 20 of about 440,892 (280)
Chemokines are a family of polypeptides that direct the migration of leukocytestoward a site of infection. They play a major role in autoimmune disease and chemokine receptors have recently been found to mediate HIV-1 fusion.
Richard Horuk
doaj +3 more sources
Antimicrobial Chemokines [PDF]
Chemokines are best known for their classic leukocyte chemotactic activity, which is critical for directing the immune response to sites of infection and injury.
Sunny C Yung, Philip M Murphy
doaj +3 more sources
Chemoattractant cytokines or chemokines constitute a family of structurally related proteins found in vertebrates, bacteria or viruses. So far, 48 chemokines genes have been identified in humans, which bind to around 20 chemokine receptors.
Xavier eBLANCHET +4 more
doaj +4 more sources
ABSTRACTIn most organs, leukocyte attachment to the endothelium of blood vessels requires capture and rolling before firm adhesion is initiated by integrin activation and/or redistribution, which can be initiated by immobilized chemokines binding their cognate receptors on rolling cells.
Klaus eLey
doaj +5 more sources
Chemokines and glycosaminoglycans [PDF]
Amanda E.I. Proudfoot
doaj +3 more sources
It is now well appreciated that chemokines play a fundamental role in various aspects of CVDs (Figure). Although numerous features of chemokine biology in relation to CVD remain to be elucidated, recent studies including those published i ATVB and highlighted herein have substantially contributed to our current knowledge on chemokines.
van der Vorst, Emiel P. C. +2 more
openaire +2 more sources
Functional diversity of chemokines and chemokine receptors in response to viral infection of the central nervous system. [PDF]
Encounters with neurotropic viruses result in varied outcomes ranging from encephalitis, paralytic poliomyelitis or other serious consequences to relatively benign infection.
A. Meyer +108 more
core +1 more source
Transplantation of human microbiota into conventional mice durably reshapes the gut microbiota
Human microbiota-associated (HMA) mice are an important model to study the relationship between liver diseases and intestinal microbiota. We describe a new method to humanize conventional mice based on bowel cleansing with polyethylene glycol followed by
Laura Wrzosek +9 more
doaj +1 more source
Chemokine Heterocomplexes and Cancer: A Novel Chapter to Be Written in Tumor Immunity
Infiltrating immune cells are a key component of the tumor microenvironment and play central roles in dictating tumor fate, either promoting anti-tumor immune responses, or sustaining tumor growth, angiogenesis and metastasis.
Gianluca D'Agostino +3 more
doaj +1 more source
Nasal Lipopolysaccharide Challenge and Cytokine Measurement Reflects Innate Mucosal Immune Responsiveness [PDF]
BackgroundPractical methods of monitoring innate immune mucosal responsiveness are lacking. Lipopolysaccharide (LPS) is a component of the cell wall of Gram negative bacteria and a potent activator of Toll-like receptor (TLR)-4.
Dhariwal, J +12 more
core +9 more sources

