Results 241 to 250 of about 149,400 (379)

SOX10, MITF, and microRNAs: Decoding their interplay in regulating melanoma plasticity

International Journal of Cancer, EarlyView.
Abstract Recent studies show that the dysregulation of the transcription factor SOX10 is essential for the development and progression of melanoma. MicroRNAs (miRNAs) can regulate the expression of transcription factors at the post‐transcriptional level. The interactions between SOX10 and its targeting miRNAs form network motifs such as feedforward and
Xin Lai, Chunyan Luan, Zhesi Zhang, Anja Wessely, Markus V. Heppt, Carola Berking, Julio Vera   +6 more
wiley   +1 more source

Targeting the FOXA1/BMI1 axis to overcome chemoresistance and suppress tumor progression in nasopharyngeal carcinoma. [PDF]

Cell Death Discov
Qin Y, Yang M, Cao Y, Fu Y, Yang F, Zhang X, Xiao S.   +6 more
europepmc   +1 more source

NF- B Activation Through the Alternative Pathway Correlates with Chemoresistance and Poor Survival in Extranodal NK/T-cell Lymphoma, Nasal Type [PDF]

, 2009
Xiaoming Liu, Bo Wang, Xuejun Ma, Y. Guo
openalex   +1 more source

Targeted reactivation of the novel tumor suppressor DAPK1, an upstream regulator of p53, in high‐grade serous ovarian cancer by mRNA liposomes reduces viability and enhances drug sensitivity in preclinical models

Cancer Communications, EarlyView.
Monika Raab, Balázs Győrffy, Samuel Peña‐Llopis, Daniela Fietz, Monika Kressin, Margareta Kolaric, Matthias Ebert, Khayal Gasimli, Sven Becker, Mourad Sanhaji, Klaus Strebhardt   +10 more
wiley   +1 more source

Artificial intelligence in the diagnosis and management of gynecologic cancer

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Gynecologic cancers affect over 1.2 million women globally each year. Early diagnosis and effective treatment are essential for improving patient outcomes, yet traditional diagnostic methods often encounter limitations, particularly in low‐resource settings.
Chaiyawut Paiboonborirak, Nadeem R. Abu‐Rustum, Sarikapan Wilailak   +2 more
wiley   +1 more source

Exosome-Mediated Chemoresistance in Cancers: Mechanisms, Therapeutic Implications, and Future Directions. [PDF]

Biomolecules
Liu G, Liu J, Li S, Zhang Y, He R.
europepmc   +1 more source

Environment, lifestyle, and cancer in women

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Environmental and lifestyle factors significantly contribute to gynecological cancers. The risk of ovarian cancer, one the most lethal gynecological cancer, is associated with obesity, poor dietary habits, and environmental pollutants, exacerbating hormonal imbalances, inflammation, and oxidative stress.
Sara Farina, Alessandra Sabatelli, Stefania Boccia, Giovanni Scambia   +3 more
wiley   +1 more source

The Mitochondrial Uncoupling Protein-2 Promotes Chemoresistance in Cancer Cells

, 2008
Zoltán Derdák, Nicholas M. Mark, Guido Beldi, Simon C. Robson, Jack R. Wands, György Baffy   +5 more
openalex   +1 more source

Upregulation of antioxidants and chemoresistance genes in human granulosa cells following Pregnane X receptor activation: a potential role for fertility preservation [PDF]

, 2009
Sana M. Salih, A. Kapur, Samet Albayrak, Charles L. Bormann   +3 more
openalex   +1 more source

Targeting the ST3 beta‐galactoside alpha‐2,3‐sialyltransferase 1 (ST3Gal1) as a potential therapeutic strategy to overcome anti‐VEGF resistance in endometrial cancer

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To investigate the role of ST3 beta‐galactoside alpha‐2,3‐sialyltransferase 1 (ST3Gal1) in endometrial cancer (EC) progression and its potential as a therapeutic target to enhance the efficacy of antiangiogenic treatment. Methods ST3Gal1 expression and its clinical relevance were analyzed in EC tissues.
Chia‐Hao Liu, Szu‐Ting Yang, Wei‐Ting Chao, Chen‐Hao Lin, Yu‐Chieh Lee, Chiung‐Ru Lai, Shie‐Liang Hsieh, Liang‐Wei Wang, Peng‐Hui Wang   +8 more
wiley   +1 more source