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Targeting of the m6A eraser ALKBH5 suppresses stemness and chemoresistance of colorectal cancer

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Heming Zhou   +17 more
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Repurposing Doxycycline to Overcome High-Glucose-Induced Mitochondrial Biogenesis-Mediated Chemoresistance in Colorectal Cancer Cells. [PDF]

open access: yesJ Cell Mol Med
Wu CH   +10 more
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CRISPR-Cas9 Genome and Double-Knockout Screening to Identify Novel Therapeutic Targets for Chemoresistance in Triple-Negative Breast Cancer. [PDF]

open access: yesCancers (Basel)
Shao S   +12 more
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Extracellular Vesicles in Chemoresistance

2021
Chemotherapy represents the current mainstay therapeutic approach for most types of cancer. Despite the development of targeted chemotherapeutic strategies, the efficacy of anti-cancer drugs is severely limited by the development of drug resistance. Multidrug resistance (MDR) consists of the simultaneous resistance to various unrelated cytotoxic drugs ...
Gabriele, De Rubis, Mary, Bebawy
openaire   +2 more sources

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