Results 1 to 10 of about 301 (95)
Metallothionein mediates leukocyte chemotaxis [PDF]
Background Metallothionein (MT) is a cysteine-rich, metal-binding protein that can be induced by a variety of agents. Modulation of MT levels has also been shown to alter specific immune functions.
Lynes Michael A +2 more
doaj +3 more sources
Signal-activated phospholipase regulation of leukocyte chemotaxis
Signal-activated phospholipases are a recent focus of the rapidly growing field of lipid signaling. The extent of their impact on the pathways regulating diverse cell functions is beginning to be appreciated.
Martha K. Cathcart
doaj +3 more sources
Combined Antiplatelet Therapy Reduces the Proinflammatory Properties of Activated Platelets
The cause of atherothrombosis is rupture or erosion of atherosclerotic lesions, leading to an increased risk of myocardial infarction or stroke. Here, platelet activation plays a major role, leading to the release of bioactive molecules, for example ...
Alexandra C.A. Heinzmann +4 more
doaj +1 more source
Here the authors use optogenetic tools to directly measure spatial signal processing in leukocyte chemotaxis. Their results reveal the importance of multiple negative feedback loops for maintaining spatial information in chemotaxis.
George R. R. Bell +3 more
doaj +1 more source
The aim of this study is to evaluate the phytochemical profile, oral acute toxicity, and the effect of ylang-ylang (Cananga odorata Hook. F. & Thomson) essential oil (YEO) on acute inflammation.
Robson Araújo de Freitas Junior +10 more
doaj +1 more source
Role of insulin hormone in modulation of inflammatory phenomena [PDF]
Evidence demonstrates the involvement of hormones in thedevelopment of inflammatory response. Inflammation evokes markedstructural alterations of microvasculature, besides migration ofleukocytes from microcirculation to the site of lesion.
Antonio Di Petta
doaj +4 more sources
Modeling leukocyte-leukocyte non-contact interactions in a lymph node. [PDF]
The interaction among leukocytes is at the basis of the innate and adaptive immune-response and it is largely ascribed to direct cell-cell contacts. However, the exchange of a number of chemical stimuli (chemokines) allows also non-contact interaction ...
Nicola Gritti +7 more
doaj +1 more source
An Agent-Based Interpretation of Leukocyte Chemotaxis in Cancer-on-Chip Experiments
The present paper was inspired by recent developments in laboratory experiments within the framework of cancer-on-chip technology, an immune-oncology microfluidic chip aiming at studying the fundamental mechanisms of immunocompetent behavior. We focus on
Gabriella Bretti, Andrea De Gaetano
doaj +1 more source
Combined boyden-flow cytometry assay improves quantification and provides phenotypification of leukocyte chemotaxis. [PDF]
Chemotaxis has been studied by classical methods that measure chemotactic and random motility responses in vitro, but these methods do not evaluate the total number and phenotype of migrating leukocytes simultaneously.
Nardhy Gomez-Lopez +2 more
doaj +1 more source
Monitoring Phosphoinositide Fluxes and Effectors During Leukocyte Chemotaxis and Phagocytosis
The dynamic re-organization of cellular membranes in response to extracellular stimuli is fundamental to the cell physiology of myeloid and lymphoid cells of the immune system.
Fernando Montaño-Rendón +7 more
doaj +1 more source

