Results 1 to 10 of about 71,798 (273)
Syk-mediated translocation of PI3Kδ to the leading edge controls lamellipodium formation and migration of leukocytes [PDF]
, 2007 The non-receptor tyrosine kinase Syk is mainly expressed in the hematopoietic system and plays an essential role in β2 integrin-mediated leukocyte activation.
Gerstl, Ronald +7 more
core +18 more sources
Combined Antiplatelet Therapy Reduces the Proinflammatory Properties of Activated Platelets
TH Open, 2021 The cause of atherothrombosis is rupture or erosion of atherosclerotic lesions, leading to an increased risk of myocardial infarction or stroke. Here, platelet activation plays a major role, leading to the release of bioactive molecules, for example ...
Alexandra C.A. Heinzmann +4 more
doaj +1 more source
Nature Communications, 2021 Here the authors use optogenetic tools to directly measure spatial signal processing in leukocyte chemotaxis. Their results reveal the importance of multiple negative feedback loops for maintaining spatial information in chemotaxis.
George R. R. Bell +3 more
doaj +1 more source
Molecules, 2022 The aim of this study is to evaluate the phytochemical profile, oral acute toxicity, and the effect of ylang-ylang (Cananga odorata Hook. F. & Thomson) essential oil (YEO) on acute inflammation.
Robson Araújo de Freitas Junior +10 more
doaj +1 more source
CCR2 acts as scavenger for CCL2 during monocyte chemotaxis. [PDF]
PLoS ONE, 2012 BACKGROUND: Leukocyte migration is essential for effective host defense against invading pathogens and during immune homeostasis. A hallmark of the regulation of this process is the presentation of chemokines in gradients stimulating leukocyte chemotaxis
Silvia Volpe +5 more
doaj +1 more source
Role of insulin hormone in modulation of inflammatory phenomena [PDF]
Einstein (São Paulo), 2011 Evidence demonstrates the involvement of hormones in thedevelopment of inflammatory response. Inflammation evokes markedstructural alterations of microvasculature, besides migration ofleukocytes from microcirculation to the site of lesion.
Antonio Di Petta
doaj +4 more sources
Modeling leukocyte-leukocyte non-contact interactions in a lymph node. [PDF]
PLoS ONE, 2013 The interaction among leukocytes is at the basis of the innate and adaptive immune-response and it is largely ascribed to direct cell-cell contacts. However, the exchange of a number of chemical stimuli (chemokines) allows also non-contact interaction ...
Nicola Gritti +7 more
doaj +1 more source
An Agent-Based Interpretation of Leukocyte Chemotaxis in Cancer-on-Chip Experiments
Mathematics, 2022 The present paper was inspired by recent developments in laboratory experiments within the framework of cancer-on-chip technology, an immune-oncology microfluidic chip aiming at studying the fundamental mechanisms of immunocompetent behavior. We focus on
Gabriella Bretti, Andrea De Gaetano
doaj +1 more source
Combined boyden-flow cytometry assay improves quantification and provides phenotypification of leukocyte chemotaxis. [PDF]
PLoS ONE, 2011 Chemotaxis has been studied by classical methods that measure chemotactic and random motility responses in vitro, but these methods do not evaluate the total number and phenotype of migrating leukocytes simultaneously.
Nardhy Gomez-Lopez +2 more
doaj +1 more source
Monitoring Phosphoinositide Fluxes and Effectors During Leukocyte Chemotaxis and Phagocytosis
Frontiers in Cell and Developmental Biology, 2021 The dynamic re-organization of cellular membranes in response to extracellular stimuli is fundamental to the cell physiology of myeloid and lymphoid cells of the immune system.
Fernando Montaño-Rendón +7 more
doaj +1 more source