Results 131 to 140 of about 19,115 (229)
This study presents an integrated anatomical, chemical, biological, and computational analysis of Myrcia sylvatica, revealing key bioactive compounds with antioxidant and toxicological potential, and identifying spathulenol and globulol as promising acetylcholinesterase inhibitors with favourable pharmacokinetic properties. ABSTRACT Myrcia sylvatica (G.
Eliza de Jesus Barros dos Santos +10 more
wiley +1 more source
Molecular Glue Degraders Redefining Targeted Therapies From Discovery to Therapeutic Applications
Molecular glue degraders (MGDs) constitute an emerging class of therapeutic agents poised to revolutionize the paradigm of targeted drug discovery. By reprogramming E3 ubiquitin ligases to degrade proteins of interest (POI) via a transient formation of a ternary complex mediated by protein–protein interactions, MGDs surpass the intrinsic limitations of
Jinfeng Wen +3 more
wiley +1 more source
Origanum vulgare L. (Lamiaceae) is widely used in the food, pharmaceutical, perfumery, and cosmetic industries for the needs for which this raw material is cultivated. O.
Ain Raal +4 more
doaj +1 more source
Dutch survey pyrrolizidine alkaloids in animal forage [PDF]
Pyrrolizidine alkaloids (PAs) are secondary plant metabolites produced by a number of plants from the Asteraceae (Compositae), Boriginaceae and Fabaceae (Leguminosae) families.
Beumer, B. +3 more
core +1 more source
ABSTRACT Gene pyramiding in crop varieties offers a promising strategy to achieve sustainable production and reduce reliance on pesticides. However, stacking resistance genes without understanding their biological functions may result in transient protection.
Romane Lapous +6 more
wiley +1 more source
Exploring Chemical Variability in the Essential Oils of the Thymus Genus
Thyme remains an indispensable herb today, finding its place in gastronomy, medicine, cosmetics, and gardens worldwide. It is highly valued in herbal remedies and pharmaceutical formulations for its antibacterial, antifungal, and antioxidant properties ...
Karim Etri, Zsuzsanna Pluhár
doaj +1 more source
Identification of candidate genes affecting Delta9-tetrahydrocannabinol biosynthesis in Cannabis sativa. [PDF]
RNA isolated from the glands of a Delta(9)-tetrahydrocannabinolic acid (THCA)-producing strain of Cannabis sativa was used to generate a cDNA library containing over 100 000 expressed sequence tags (ESTs).
Dixon, Richard A +8 more
core
Chemical and mechanical defences of a metal‐hyperaccumulating plant species Arabidopsis halleri were more influenced by plant accession (genetic background) and insect herbivory by a leaf beetle Phaedon cochleariae than by supplementation of the metalloid silicon.
R. Putra, M. Paulic, C. Müller
wiley +1 more source
SUMMARY Glycosyltransferases (GTs) are the primary enzymes responsible for the biosynthesis of the complex polysaccharides in plant cell walls. Given the important role of GTs in plants, it is necessary to undertake their functional characterization to better understand plant cell wall synthesis pathways to develop improved feedstocks for efficient ...
Charles J. Corulli +9 more
wiley +1 more source
Significance Statement This study of three glandular trichome‐producing species (cannabis, hop and tomato) defines tissue‐specific transcriptomic atlases for five organs (trichome, flower, leaf, stem and root), providing co‐expression and gene regulatory networks and identifying candidate regulators of specialised metabolism in trichomes of each ...
Muluneh Tamiru‐Oli +10 more
wiley +1 more source

