B-Cell Epitopes-Based Chimeric Protein from SARS-CoV-2 N and S Proteins Is Recognized by Specific Antibodies in Serum and Urine Samples from Patients [PDF]
Viruses, 2023 The impact of the COVID-19 pandemic caused by the SARS-CoV-2 virus underscored the crucial role of laboratorial tests as a strategy to control the disease, mainly to indicate the presence of specific antibodies in human samples from infected patients ...
Fernanda F. Ramos +23 more
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Development and application of an indirect ELISA to detect antibodies to Neospora caninum in cattle based on a chimeric protein rSRS2-SAG1-GRA7 [PDF]
Frontiers in Veterinary Science, 2022 Neospora caninum is an important apicomplexan parasite causing neosporosis in cattle. The disease is recognized as one of the most important cause of reproductive problems and abortion in cattle worldwide. In this context, we developed an indirect enzyme-
Cong-Shan Yang +12 more
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Assessing of the use of proteins A, G, and chimeric protein AG to detect marine mammal immunoglobulins. [PDF]
PLoS ONE, 2023 In recent years, there has been an increase in infectious diseases in marine mammals, including brucellosis, infections of morbillivirus, herpesvirus, and poxvirus.
Michael Essien Sakyi +6 more
doaj +2 more sources
A New Recombinant Multiepitope Chimeric Protein of Leptospira interrogans Is a Promising Marker for the Serodiagnosis of Leptospirosis [PDF]
Tropical Medicine and Infectious Disease, 2022 The zoonotic disease leptospirosis is caused by pathogenic species of the genus Leptospira and was recently included in the list of Neglected Diseases by the World Health Organization.
Luis G. V. Fernandes +5 more
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Immunotherapeutics Combining a Recombinant Chimeric Protein, Monophosphoryl Lipid A, and Miltefosine Against Visceral Leishmaniasis [PDF]
PathogensCurrent treatment for visceral leishmaniasis (VL) is associated with toxicity, a high cost, and the emergence of drug-resistant parasite strains. Moreover, no human vaccine is available.
Marcelo M. Jesus +19 more
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A chimeric protein-based vaccine elicits a strong IgG antibody response and confers partial protection against Shiga toxin-producing Escherichia coli in mice [PDF]
Frontiers in Immunology, 2023 BackgroundShiga toxin-producing Escherichia coli (STEC) is a foodborne pathogen that causes gastrointestinal infections, ranging from acute diarrhea and dysentery to life-threatening diseases such as Hemolytic Uremic Syndrome.
David A. Montero +19 more
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A novel recombinant chimeric bio-adhesive protein consisting of mussel foot protein 3, 5, gas vesicle protein A, and CsgA curli protein expressed in Pichia pastoris [PDF]
AMB Express, 2022 Keypoints A chimeric bioinspired adhesive protein has been generated for use in wet condition Enhanced adhesion strength of chimeric protein due to the curli proteins GvpA and CsgA Amyloid structure of GvpA and CsgA led to efficient self-assembly of ...
Nazanin Bolghari +3 more
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A review of chimeric proteins/enzymes [PDF]
BIO Web of ConferencesThe low homologous protein chimeric recombination technique by rational design of mutant library proteins in the construction of chimeric esterases by structural domain recombination often produces a large number of inclusion bodies due to misfolding of ...
Zhu Jiakang, Han Song, Gao Le
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Chimeric Protein IPath® with Chelating Activity Improves Atlantic Salmon’s Immunity against Infectious Diseases [PDF]
Vaccines, 2021 Infection processes displayed by pathogens require the acquisition of essential inorganic nutrients and trace elements from the host to survive and proliferate.
Valentina Valenzuela-Muñoz +4 more
doaj +2 more sources
Intratumoral immunotherapy with mRNAs encoding chimeric protein constructs encompassing IL-12, CD137 agonists, and TGF-β antagonists. [PDF]
Mol Ther Nucleic Acids, 2023 Cirella A +18 more
europepmc +3 more sources