Results 11 to 20 of about 311,648 (345)

Evaluation of Trichodysplasia Spinulosa-Associated Polyomavirus Capsid Protein as a New Carrier for Construction of Chimeric Virus-Like Particles Harboring Foreign Epitopes

Viruses, 2015
Recombinant virus-like particles (VLPs) represent a promising tool for protein engineering. Recently, trichodysplasia spinulosa-associated polyomavirus (TSPyV) viral protein 1 (VP1) was efficiently produced in yeast expression system and shown to self ...
Alma Gedvilaite, Indre Kucinskaite-Kodze, Rita Lasickiene, Albertas Timinskas, Ausra Vaitiekaite, Danguole Ziogiene, Aurelija Zvirbliene   +6 more
doaj   +3 more sources

Molecular Interaction-Based Exploration of the Broad Spectrum Efficacy of a Bacillus thuringiensis Insecticidal Chimeric Protein, Cry1AcF

Toxins, 2019
Bacillus thuringiensis insecticidal proteins (Bt ICPs) are reliable and valuable options for pest management in crops. Protein engineering of Bt ICPs is a competitive alternative for resistance management in insects. The primary focus of the study was to
Maniraj Rathinam, Karthik Kesiraju, Shweta Singh, Vinutha Thimmegowda, Vandna Rai, Debasis Pattanayak, Rohini Sreevathsa   +6 more
doaj   +3 more sources

Investigation of Niosomes for use as brucellosis vaccine [PDF]

Novelty in Clinical Medicine, 2023
Background: Niosomes are vesicles, a new drug delivery system, which can be It is used for sustained, controlled as well as targeted delivery of drugs.
Ahmad Abolfathiniya, Mahdi Fasihi-ramandi, Zeinab Tabanejad   +2 more
doaj   +1 more source

Envelope Determinants of Equine Lentiviral Vaccine Protection [PDF]

, 2013
Lentiviral envelope (Env) antigenic variation and associated immune evasion present major obstacles to vaccine development. The concept that Env is a critical determinant for vaccine efficacy is well accepted, however defined correlates of protection ...
A Kumar, A Kumar, AJ Mcmichael, AT Das, B Berkhout, BA Sponseller, BF Haynes, C Leroux, C Leroux, C Leroux, CH Grund, Charles J. Issel, CJ Issel, Corin Ezzelarab, D Shental-Bechor, David Horohov, DC Montefiori, DL Lichtenstein, DL Lichtenstein, EW Uhl, F Li, F Li, F Li, J Mills, JB Whitney, JK Craigo, JK Craigo, JK Craigo, JK Craigo, JK Craigo, JK Craigo, JK Craigo, JK Craigo, JM Ball, Jodi K. Craigo, K Abel, KA Hussain, L Coggins, L Howe, L Howe, Liu Chong, M Busch, MJ Papandreou, ML Raabe, MR Raabe, MR Reynolds, N Almond, PM Rwambo, PM Rwambo, R Hofmann-Lehmann, RC Montelaro, RF Cook, RM Ruprecht, Ronald C. Montelaro, RP Johnson, RP Johnson, RP Johnson, RR Amara, S Hambleton, SA Hammond, SA Hammond, SA Hammond, Sheila J. Cook, SL Payne, SM Blower, SM Harrold, SZ Wang, TL Tagmyer, TL Tagmyer, TW Baba, TW Baba, WC Koff, WM Bogers, Y Kono, YH Zheng, YH Zheng, Zhiping Ye   +76 more
core   +12 more sources

Characterization of the Chimeric PriB-SSBc Protein [PDF]

International Journal of Molecular Sciences, 2021
PriB is a primosomal protein required for the replication fork restart in bacteria. Although PriB shares structural similarity with SSB, they bind ssDNA differently. SSB consists of an N-terminal ssDNA-binding/oligomerization domain (SSBn) and a flexible C-terminal protein–protein interaction domain (SSBc).
En-Shyh Lin, Yen-Hua Huang, Cheng-Yang Huang   +2 more
openaire   +2 more sources

Evaluation of chimeric proteins for serological diagnosis of brucellosis in cattle [PDF]

Veterinary World, 2021
Background and Aim: An accurate diagnosis of Brucella-infected animals is one of the critical measures in eradication programs. Conventional serological tests based on whole-cell (WC) antigens and detecting antibodies against pathogen-associated ...
Aitbay K. Bulashev, Bakytkali K. Ingirbay, Kanatbek N. Mukantayev, Alfiya S. Syzdykova   +3 more
doaj   +1 more source

In silico Analysis, Molecular Docking, Molecular Dynamic, Cloning, Expression and Purification of Chimeric Protein in Colorectal Cancer Treatment

Drug Design, Development and Therapy, 2020
Hassan Dana, 1, 2,* Ghanbar Mahmoodi Chalbatani, 1,* Elahe Gharagouzloo, 1 Seyed Rouhollah Miri, 1 Fereidoon Memari, 1 Reza Rasoolzadeh, 3 Mohammad Reza Zinatizadeh, 3 Peyman Kheirandish Zarandi, 3 Vahid Marmari 2 1Cancer Research Center, Cancer ...
Dana H, Mahmoodi Chalbatani G, Gharagouzloo E, Miri SR, Memari F, Rasoolzadeh R, Zinatizadeh MR, Kheirandish Zarandi P, Marmari V   +8 more
doaj   +1 more source

Development of modern immunization agent against bovine papillomavirus type 1 infection based on BPV1 L1 recombinant protein

Frontiers in Veterinary Science, 2023
Bovine papillomavirus type 1 L1 protein was produced in a baculovirus expression system and purified as virus-like particles (VLPs) by affinity chromatography using lectins.
Alena Vrablikova, Veronika Brezani, Ivan Psikal, Ivan Psikal, Martin Fraiberk, Martin Fraiberk, Marek Sebela, Martina Fojtikova, Pavel Kulich, Renata Hezova, Josef Masek   +10 more
doaj   +1 more source

Potential role of chimeric genes in pathway-related gene co-expression modules

World Journal of Surgical Oncology, 2021
Background Gene fusion has epigenetic modification functions. The novel proteins encoded by gene fusion products play a role in cancer development. Therefore, a better understanding of the novel protein products may provide insights into the pathogenesis
Piaopiao Li, Yingxia Li, Lei Ma
doaj   +1 more source

Flagellin Improves the Immune Response of an Infectious Bursal Disease Virus (IBDV) Subunit Vaccine

Vaccines, 2022
Flagellin activates the immune system through Toll-like receptor 5 (TLR5) and can work as an adjuvant for subunit vaccines. In this study, we tested the adjuvancy of two different N-terminal fragments of flagellin, (1) FliC99, residues 1–99, and (2 ...
Asad Murtaza, Haroon Afzal, Thu-Dung Doan, Guan-Ming Ke, Li-Ting Cheng   +4 more
doaj   +1 more source