Results 11 to 20 of about 254,758 (298)

Screening of viral-vectored P. falciparum pre-erythrocytic candidate vaccine antigens using chimeric rodent parasites.

PLoS ONE, 2021
To screen for additional vaccine candidate antigens of Plasmodium pre-erythrocytic stages, fourteen P. falciparum proteins were selected based on expression in sporozoites or their role in establishment of hepatocyte infection. For preclinical evaluation
Surendra Kumar Kolli, Ahmed M Salman, Jai Ramesar, Severine Chevalley-Maurel, Hans Kroeze, Fiona G A Geurten, Shinya Miyazaki, Ekta Mukhopadhyay, Catherin Marin-Mogollon, Blandine Franke-Fayard, Adrian V S Hill, Chris J Janse   +11 more
doaj   +1 more source

Exploitation of Novel Bt ICPs for the Management of Helicoverpa armigera (Hübner) in Cotton (Gossypium hirsutum L.): A Transgenic Approach

Frontiers in Microbiology, 2021
Cotton is a commercial crop of global importance. The major threat challenging the productivity in cotton has been the lepidopteron insect pest Helicoverpa armigera or cotton bollworm which voraciously feeds on various plant parts.
Kesiraju Karthik, Jyotsana Negi, Maniraj Rathinam, Navinder Saini, Rohini Sreevathsa   +4 more
doaj   +1 more source

Efficient cellular and humoral immune response and production of virus-neutralizing antibodies by the Hepatitis B Virus S/preS116-42 antigen

Frontiers in Immunology, 2022
Despite the availability of improved antiviral therapies, infection with Hepatitis B virus (HBV) remains a3 significant health issue, as a curable treatment is yet to be discovered.
Ana-Maria Pantazica, Mihaela-Olivia Dobrica, Catalin Lazar, Cristina Scurtu, Catalin Tucureanu, Iuliana Caras, Irina Ionescu, Adriana Costache, Adrian Onu, Jihong Liu Clarke, Crina Stavaru, Norica Branza-Nichita   +11 more
doaj   +1 more source

Systematic identification and comparative analysis of lysine succinylation between the green and white parts of chimeric leaves of Ananas comosus var. bracteatus

BMC Genomics, 2020
Background Lysine succinylation, an important protein posttranslational modification (PTM), is widespread and conservative. The regulatory functions of succinylation in leaf color has been reported. The chimeric leaves of Ananas comosus var.
Meiqin Mao, Yanbin Xue, Yehua He, Xuzixing Zhou, Fatima Rafique, Hao Hu, Jiawen Liu, Lijun Feng, Wei Yang, Xi Li, Lingxia Sun, Zhuo Huang, Jun Ma   +12 more
doaj   +1 more source

Genotypic and Phenotypic Characteristics of Acute Promyelocytic Leukemia Translocation Variants

Hematology/Oncology and Stem Cell Therapy, 2020
Acute promyelocytic leukemia (APL) is a special disease entity of acute myeloid leukemia (AML). The clinical use of all-trans retinoic acid (ATRA) has transformed APL into the most curable form of AML.
Abdul Mannan, Ibrahim N. Muhsen, Eva Barragán, Miguel A. Sanz, Mohamad Mohty, Shahrukh K. Hashmi, Mahmoud Aljurf   +6 more
doaj   +1 more source

Vascular regeneration in a basal chordate is due to the presence of immobile, bi-functional cells. [PDF]

, 2013
The source of tissue turnover during homeostasis or following injury is usually due to proliferation of a small number of resident, lineage-restricted stem cells that have the ability to amplify and differentiate into mature cell types.
Braden, Brian P, De Tomaso, Anthony W, Kassmer, Susannah, Lewis, Daniel D, Pierce, James D, Taketa, Daryl A   +5 more
core   +8 more sources

The B7-1 cytoplasmic tail enhances intracellular transport and mammalian cell surface display of chimeric proteins in the absence of a linear ER export motif. [PDF]

PLoS ONE, 2013
Membrane-tethered proteins (mammalian surface display) are increasingly being used for novel therapeutic and biotechnology applications. Maximizing surface expression of chimeric proteins on mammalian cells is important for these applications.
Yi-Chieh Lin, Bing-Mae Chen, Wei-Cheng Lu, Chien-I Su, Zeljko M Prijovich, Wen-Chuan Chung, Pei-Yu Wu, Kai-Chuan Chen, I-Chiao Lee, Ting-Yi Juan, Steve R Roffler   +10 more
doaj   +1 more source

Selective Degradation of Target Proteins by Chimeric Small-Molecular Drugs, PROTACs and SNIPERs

Pharmaceuticals, 2020
New therapeutic modalities are needed to address the problem of pathological but undruggable proteins. One possible approach is the induction of protein degradation by chimeric drugs composed of a ubiquitin ligase (E3) ligand coupled to a ligand for the ...
Minoru Ishikawa, Shusuke Tomoshige, Yosuke Demizu, Mikihiko Naito   +3 more
doaj   +1 more source

Assessing of the use of proteins A, G, and chimeric protein AG to detect marine mammal immunoglobulins.

PLoS ONE, 2023
In recent years, there has been an increase in infectious diseases in marine mammals, including brucellosis, infections of morbillivirus, herpesvirus, and poxvirus.
Michael Essien Sakyi, Takashi Kamio, Kaoru Kohyama, Md Matiur Rahman, Kaori Shimizu, Ayaka Okada, Yasuo Inoshima   +6 more
doaj   +1 more source

Structural modeling, expression and purification of Chimeric chitinase 42 containing His-tag in Nicotiana tabacum hairy root system [PDF]

Journal of Agricultural Sciences (Belgrade), 2023
Chimeric chitinase42 (Chit42 containing ChBD) has great potential as a candidate for digesting and recycling chitin as a beneficial nutrient, which can be produced in bioreactors.
Soleimani Faranak, Motallebi Mostafa, Zamani Mohammadreza, Jourabchi Esmat   +3 more
doaj   +1 more source