Results 1 to 10 of about 5,931 (188)
Combined transcriptomic and ChIPseq analyses of the Bordetella pertussis RisA regulon [PDF]
MSystemsThe regulation of Bordetella pertussis virulence is mediated by the two-component system BvgA/S, which activates the transcription of virulence-activated genes (vags).
Loïc Coutte +2 more
exaly +6 more sources
Combined RNAseq and ChIPseq Analyses of the BvgA Virulence Regulator of Bordetella pertussis [PDF]
MSystems, 2020 Bordetella pertussis regulates the production of its virulence factors by the two-component system BvgAS. In the virulence phase, BvgS phosphorylates BvgA, which then activates the transcription of virulence-activated genes (vags).
Loïc Coutte, Rudy Antoine, Luis Solans
exaly +10 more sources
High-throughput ChIPmentation: freely scalable, single day ChIPseq data generation from very low cell-numbers [PDF]
BMC Genomics, 2019 Background Chromatin immunoprecipitation coupled to sequencing (ChIP-seq) is widely used to map histone modifications and transcription factor binding on a genome-wide level.
Charlotte Gustafsson +2 more
exaly +5 more sources
An effective statistical evaluation of ChIPseq dataset similarity [PDF]
Bioinformatics, 2012 Abstract Motivation: ChIPseq is rapidly becoming a common technique for investigating protein–DNA interactions. However, results from individual experiments provide a limited understanding of chromatin structure, as various chromatin factors cooperate in complex ways to orchestrate transcription.
Olga G Troyanskaya
exaly +3 more sources
A Novel Bayesian Change-point Algorithm for Genome-wide Analysis of Diverse ChIPseq Data Types [PDF]
Journal of Visualized Experiments, 2012 ChIPseq is a widely used technique for investigating protein-DNA interactions. Read density profiles are generated by using next-sequencing of protein-bound DNA and aligning the short reads to a reference genome. Enriched regions are revealed as peaks, which often differ dramatically in shape, depending on the target protein(1).
Michael Q Zhang
exaly +5 more sources
Frontiers in Immunology, 2021 Peripheral neutrophils in HIV-infected individuals are characterized by impairment of chemotaxis, phagocytosis, bactericidal activity, and oxidative burst ability regardless of whether patients are receiving antiretroviral therapy or not.
Paweł Piatek +2 more
exaly +3 more sources
Blood, 2016 Abstract The KLF1 transcription factor regulates a large set of genes during erythroid differentiation and promotes the developmental switch from fetal to adult globin by directly activating the adult β-globin gene as well as Bcl11a, a major repressor of fetal globin expression.
Kevin Robert Gillinder +2 more
exaly +2 more sources
Genome-Wide ChIPseq Analysis of AhR, COUP-TF, and HNF4 Enrichment in TCDD-Treated Mouse Liver [PDF]
International Journal of Molecular Sciences, 2021 The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor known for mediating the toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and related compounds. Although the canonical mechanism of AhR activation involves heterodimerization with the aryl hydrocarbon receptor nuclear translocator, other transcriptional regulators that
Giovan N. Cholico +2 more
openaire +3 more sources
Communications Biology, 2022 Changes in chromatin accessibility occuring during the process of allopolyploidization of Brassica napus are analysed using ATAC and ChIPseq, with differences in asymmetric chromatin accessibility between subgenomes of B. napus investigated.
Zeyu Li, Mengdi Li, Jianbo Wang
doaj +1 more source
Chromatin-bound protein colocalization analysis using bedGraph2Cluster and PanChIP
STAR Protocols, 2023 Summary: Computational pipelines for chromatin immunoprecipitation sequencing analysis can neglect colocalization events that occur in a mere subset of the genome.
Hanjun Lee +3 more
doaj +1 more source