Results 11 to 20 of about 328,477 (299)
Chloride channels in stroke [PDF]
Acta Pharmacologica Sinica, 2012 Vascular remodeling of cerebral arterioles, including proliferation, migration, and apoptosis of vascular smooth muscle cells (VSMCs), is the major cause of changes in the cross-sectional area and diameter of the arteries and sudden interruption of blood flow or hemorrhage in the brain, ie, stroke.
Ya-ping, Zhang +2 more
openaire +2 more sources
Impact of chloride channel on firing patterns of the fractional-order Morris–Lecar model
Results in Applied Mathematics, 2022 Fractional calculus as a new approach for modeling has been used widely to study the non-linear behavior of physical and biological systems with some degrees of fractionality or fractality using differential and integral operators with non integer-orders.
Tahmineh Azizi
doaj +1 more source
Structural and Biophysical Analysis of the CLCA1 VWA Domain Suggests Mode of TMEM16A Engagement
Cell Reports, 2020 Summary: The secreted protein calcium-activated chloride channel regulator 1 (CLCA1) utilizes a von Willebrand factor type A (VWA) domain to bind to and potentiate the calcium-activated chloride channel TMEM16A.
Kayla N. Berry, Tom J. Brett
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secCl is a cys-loop ion channel necessary for the chloride conductance that mediates hormone-induced fluid secretion in Drosophila [PDF]
, 2019 Organisms use circulating diuretic hormones to control water balance (osmolarity), thereby avoiding dehydration and managing excretion of waste products.
Dent, J. +6 more
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Frontiers in Genetics, 2023 Myotonia congenita (MC) is a rare neuromuscular disease caused by mutations within the CLCN1 gene encoding skeletal muscle chloride channels. MC is characterized by delayed muscle relaxation during contraction, resulting in muscle stiffness.
Nurul Huda Musa +16 more
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Molecular mechanisms of Cys-loop ion channel receptor modulation by ivermectin
Frontiers in Molecular Neuroscience, 2012 Ivermectin is a gold standard anthelmintic drug that works by potently depressing neuronal activity and muscular contractility in arthropods and nematodes. At the molecular level, ivermectin activates inhibitory glutamate-gated chloride channels (GluClRs)
Timothy eLynagh, Joe eLynch
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Chloride – The Underrated Ion in Nociceptors
Frontiers in Neuroscience, 2020 In contrast to pain processing neurons in the spinal cord, where the importance of chloride conductances is already well established, chloride homeostasis in primary afferent neurons has received less attention.
Bettina U. Wilke +3 more
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A chloride channel in rat and human axons [PDF]
, 1991 Current recordings from single chloride channels were obtained from excised and cell-attached patches of rat and human axons. In rat axons the channels showed an outwardly rectifying current-voltage relationship with a slope conductance of 33 pS at ...
Baker +19 more
core +1 more source
Roles of the ClC chloride channel CLH-1 in food-associated salt chemotaxis behavior of C. elegans
eLife, 2021 The ability of animals to process dynamic sensory information facilitates foraging in an ever-changing environment. However, molecular and neural mechanisms underlying such ability remain elusive.
Chanhyun Park +5 more
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Regulation of fast-spiking basket cell synapses by the chloride channel ClC-2. [PDF]
, 2010 Parvalbumin-expressing, fast-spiking basket cells are important for the generation of synchronous, rhythmic population activities in the hippocampus. We found that GABAA receptor-mediated synaptic inputs from murine parvalbumin-expressing basket cells ...
Földy, Csaba +3 more
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