Results 51 to 60 of about 296,529 (174)
PLoS ONE, 2013 BackgroundAltered chloride homeostasis has been thought to be a risk factor for several brain disorders, while less attention has been paid to its role in liver disease.
Yan-Ling Yang +6 more
doaj +1 more source
Reciprocal Regulation of KCC2 Trafficking and Synaptic Activity
Frontiers in Cellular Neuroscience, 2019 The main inhibitory neurotransmitter receptors in the adult central nervous system (CNS) are type A γ-aminobutyric acid receptors (GABAARs) and glycine receptors (GlyRs).
Etienne Côme +14 more
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Claudins in the Renal Collecting Duct [PDF]
, 2019 The renal collecting duct fine-tunes urinary composition, and thereby, coordinates key physiological processes, such as volume/blood pressure regulation, electrolyte-free water reabsorption, and acid-base homeostasis.
Leiz, Janna, Schmitt-Ott, Kai M.
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The yeast CLC chloride channel functions in cation homeostasis [PDF]
Proceedings of the National Academy of Sciences, 1998 A defect in the yeast GEF1 gene, a CLC chloride channel homolog leads to an iron requirement and cation sensitivity. The iron requirement is due to a failure to load Cu 2+ onto a component of the iron uptake system, Fet3. This process, which requires both Gef1 and the Menkes disease Cu
R A, Gaxiola +3 more
openaire +2 more sources
Cellular Physiology and Pathophysiology of EAAT Anion Channels
Frontiers in Cellular Neuroscience, 2022 Excitatory amino acid transporters (EAATs) optimize the temporal resolution and energy demand of mammalian excitatory synapses by quickly removing glutamate from the synaptic cleft into surrounding neuronal and glial cells and ensuring low resting ...
Peter Kovermann +3 more
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Versatility of NaCl transport mechanisms in the cortical collecting duct [PDF]
, 2017 Versatility of NaCl transport mechanisms in the cortical collecting duct. Am J Physiol Renal Physiol 313: F1254 –F1263, 2017. First published September 6, 2017; doi:10.1152/ajprenal.00369.2017.—The cortical collecting duct (CCD) forms part of the ...
Crambert, Gilles, Edwards, Aurelie
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Frontiers in Cellular Neuroscience, 2016 The proliferative pool of neural progenitor cells is maintained by exquisitely controlled mechanisms for cell cycle regulation. The Na-K-Cl cotransporter NKCC1 is important for regulating cell volume and the proliferation of different cell types in vitro.
Ana Cathia Magalhães +3 more
doaj +1 more source
Restoring Conjunctival Tolerance by Topical Nuclear Factor–κB Inhibitors Reduces Preservative-Facilitated Allergic Conjunctivitis in Mice [PDF]
, 2014 Purpose.: To evaluate the role of nuclear factor–κB (NF-κB) activation in eye drop preservative toxicity and the effect of topical NF-κB inhibitors on preservative-facilitated allergic conjunctivitis.
Gabelloni, María Laura +6 more
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Frontiers in Neural Circuits, 2014 The central pattern generators (CPGs) for locomotion, located in the lumbar spinal cord, are functional at birth in the rat. Their maturation occurs during the last few days preceding birth, a period during which the first projections from the brainstem ...
Laurent eVinay, Florian eGackière
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Frontiers in Cellular Neuroscience, 2020 γ-Aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the mature brain but has the paradoxical property of depolarizing neurons during early development.
Christopher K. Salmon +10 more
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