Results 41 to 50 of about 296,529 (174)

Regulation of Neuronal Chloride Homeostasis by Pro- and Mature Brain-Derived Neurotrophic Factor (BDNF) via KCC2 Cation-Chloride Cotransporters in Rat Cortical Neurons. [PDF]

Int J Mol Sci
Hamze M, Brier C, Buhler E, Zhang J, Medina I, Porcher C.   +5 more
europepmc   +2 more sources

The effects of chloride dynamics on substantia nigra pars reticulata responses to pallidal and striatal inputs

eLife, 2020
As a rodent basal ganglia (BG) output nucleus, the substantia nigra pars reticulata (SNr) is well positioned to impact behavior. SNr neurons receive GABAergic inputs from the striatum (direct pathway) and globus pallidus (GPe, indirect pathway). Dominant
Ryan S Phillips, Ian Rosner, Aryn H Gittis, Jonathan E Rubin   +3 more
doaj   +1 more source

WNK3 kinase maintains neuronal excitability by reducing inwardly rectifying K+ conductance in layer V pyramidal neurons of mouse medial prefrontal cortex

Frontiers in Molecular Neuroscience, 2022
The with-no-lysine (WNK) family of serine-threonine kinases and its downstream kinases of STE20/SPS1-related proline/alanine-rich kinase (SPAK) and oxidative stress-responsive kinase-1 (OSR1) may regulate intracellular Cl− homeostasis through ...
Adya Saran Sinha, Tianying Wang, Miho Watanabe, Yasushi Hosoi, Eisei Sohara, Tenpei Akita, Shinichi Uchida, Atsuo Fukuda   +7 more
doaj   +1 more source

Nucleus-Specific Chloride Homeostasis in Rat Thalamus [PDF]

The Journal of Neuroscience, 1997
Synchronous thalamic network activity occurring during slow wave sleep and paroxysmal discharges critically depends on the ability of thalamocortical relay cells and inhibitory neurons of the nucleus reticularis thalami (nRt) to fire bursts of action potentials.
D, Ulrich, J R, Huguenard
openaire   +2 more sources

TGF-β2 Regulates Transcription of the K⁺/Cl⁻ Cotransporter 2 (KCC2) in Immature Neurons and Its Phosphorylation at T1007 in Differentiated Neurons

Cells, 2022
KCC2 mediates extrusion of K+ and Cl− and assuresthe developmental “switch” in GABA function during neuronal maturation. However, the molecular mechanisms underlying KCC2 regulation are not fully elucidated.
Anastasia Rigkou, Attila Magyar, Jan Manuel Speer, Eleni Roussa   +3 more
doaj   +1 more source

The Kainate Receptor Subunit GluK2 Interacts With KCC2 to Promote Maturation of Dendritic Spines

Frontiers in Cellular Neuroscience, 2020
Kainate receptors (KAR) play a crucial role in the plasticity and functional maturation of glutamatergic synapses. However, how they regulate structural plasticity of dendritic spines is not known.
Sebnem Kesaf, Sebnem Kesaf, Stanislav Khirug, Emilie Dinh, Marta Saez Garcia, Shetal Soni, Ester Orav, Ester Orav, Eric Delpire, Tomi Taira, Tomi Taira, Sari E. Lauri, Sari E. Lauri, Claudio Rivera, Claudio Rivera   +14 more
doaj   +1 more source

Vapor nanobubble is the more reliable photothermal mechanism for inducing endosomal escape of siRNA without disturbing cell homeostasis [PDF]

, 2020
Strategies for controlled delivery of therapeutic siRNA into living cells are in high demand as endosomal escape remains the most prominent bottleneck at the intracellular level.
Barriga, Gerardo Garcia-Diaz, Braeckmans, Kevin, Brans, Toon, De Keulenaer, Sarah, De Rycke, Riet, De Smedt, Stefaan, De Vos, Winnok H., Fraire, Juan, Houthaeve, Gaëlle, Liu, Jing, Mestdagh, Pieter, Raemdonck, Koen, Raes, Laurens, Stremersch, Stephan, Van Nieuwerburgh, Filip, Vandesompele, Jo, Vermeulen, Lotte   +16 more
core   +3 more sources

Control of circadian rhythm on cortical excitability and synaptic plasticity

Frontiers in Neural Circuits, 2023
Living organisms navigate through a cyclic world: activity, feeding, social interactions are all organized along the periodic succession of night and day.
Claudia Lodovichi, Claudia Lodovichi, Claudia Lodovichi, Gian Michele Ratto, Gian Michele Ratto, Gian Michele Ratto   +5 more
doaj   +1 more source

Effects of a Four-Week High-Dosage Zinc Oxide Supplemented Diet on Commensal Escherichia coli of Weaned Pigs [PDF]

, 2019
Strategies to reduce economic losses associated with post-weaning diarrhea in pig farming include high-level dietary zinc oxide supplementation.
Bethe, Astrid, Eichhorn, Inga, Epping, Lennard, Ghazisaeedi, Fereshteh, Johanns, Vanessa C., Lübke-Becker, Antina, Merle, Roswitha, Pfeifer, Yvonne, Semmler, Torsten, Walther, Birgit, Wieler, Lothar H.   +10 more
core   +2 more sources

A Short Review on the Development of Salt Tolerant Cultivars in Rice [PDF]

, 2016
Rice is staple food for half of the world. With a population of almost 9.6 billion by the year 2050, there is a dire need of developing techniques to improve the crop plants, not only in terms of better yield but also to withstand harsh environmental ...
Jahan, N. (Nusrat), Javed, M. A. (Muhammad), Khan, S. (Samiullah), Manan, F. A. (Fazilah)   +3 more
core   +4 more sources