Results 41 to 50 of about 839,045 (255)

Development and regulation of chloride homeostasis in the central nervous system. [PDF]

open access: yesFront Cell Neurosci, 2015
γ-Aminobutyric acid (GABA) is the main inhibitory neurotransmitter of the mature central nervous system (CNS). The developmental switch of GABAergic transmission from excitation to inhibition is induced by changes in Cl(-) gradients, which are generated by cation-Cl(-) co-transporters.
Watanabe M, Fukuda A.
europepmc   +5 more sources

Serotonergic modulation of post-synaptic inhibition and locomotor alternating pattern in the spinal cord

open access: yesFrontiers in Neural Circuits, 2014
The central pattern generators (CPGs) for locomotion, located in the lumbar spinal cord, are functional at birth in the rat. Their maturation occurs during the last few days preceding birth, a period during which the first projections from the brainstem ...
Laurent eVinay, Florian eGackière
doaj   +1 more source

Control of circadian rhythm on cortical excitability and synaptic plasticity

open access: yesFrontiers in Neural Circuits, 2023
Living organisms navigate through a cyclic world: activity, feeding, social interactions are all organized along the periodic succession of night and day.
Claudia Lodovichi   +5 more
doaj   +1 more source

The yeast CLC chloride channel functions in cation homeostasis [PDF]

open access: yesProceedings of the National Academy of Sciences, 1998
A defect in the yeast GEF1 gene, a CLC chloride channel homolog leads to an iron requirement and cation sensitivity. The iron requirement is due to a failure to load Cu 2+ onto a component of the iron uptake system, Fet3.
R A, Gaxiola   +3 more
openaire   +2 more sources

Importance of Abnormal Chloride Homeostasis in Stable Chronic Heart Failure. [PDF]

open access: yesCirc Heart Fail, 2016
Background— The aim of this analysis was to determine the long-term prognostic value of lower serum chloride in patients with stable chronic heart failure. Electrolyte abnormalities are prevalent in patients with chronic heart failure. Little is known regarding the prognostic implications of lower serum chloride.
Grodin JL   +5 more
europepmc   +5 more sources

Chloride diffusion coeficient determination for specifications [PDF]

open access: yes, 2005
Presented at the 6th International Congress on Global Construction, Dundee, ScotlandThe chloride diffusion resistance of reinforced concrete can have a major influence on durability.
Richardson, Mark G.   +3 more
core   +1 more source

Exercise modulates chloride homeostasis after spinal cord injury. [PDF]

open access: yesJ Neurosci, 2014
Activity-based therapies are routinely integrated in spinal cord injury (SCI) rehabilitation programs because they result in a reduction of hyperreflexia and spasticity. However, the mechanisms by which exercise regulates activity in spinal pathways to reduce spasticity and improve functional recovery are poorly understood.
Côté MP   +3 more
europepmc   +4 more sources

Depolarizing GABA Transmission Restrains Activity-Dependent Glutamatergic Synapse Formation in the Developing Hippocampal Circuit

open access: yesFrontiers in Cellular Neuroscience, 2020
γ-Aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the mature brain but has the paradoxical property of depolarizing neurons during early development.
Christopher K. Salmon   +10 more
doaj   +1 more source

Phospho-dependent modulation of potassium chloride co-transporter KCC2 [PDF]

open access: yes, 2009
The neuronal-specific potassium chloride co-transporter 2, KCC2, is a major chloride extruder in brain. The expression of KCC2 during neuronal development is fundamental to the switch of GABAergic response from excitatory to inhibitory. Malfunction of
Lee, H.C.
core  

The actions of chloride channel blockers, barbiturates and a benzodiazepine on Caenorhabditis elegans glutamate- and ivermectin-gated chloride channel subunits expressed in Xenopus oocytes [PDF]

open access: yes, 2009
The pharmacology of Caenorhabditis elegans glutamate-gated chloride (GluCl) channels was determined by making intracellular voltage-clamp recordings from Xenopus oocytes expressing GluCl subunits. As previously reported (Cully et al.
Bush, Elizabeth   +3 more
core   +1 more source

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