Results 61 to 70 of about 6,798 (251)

COVID-19-Related Cholangiopathy: Histological Findings

Diagnostics
Cholangiopathy has been described in survivors of severe COVID-19, presenting significant clinical parallels to the pre-pandemic condition of secondary sclerosing cholangitis in critically ill patients (SSC-CIP).
Valéria F. A. Borges, Helma P. Cotrim, Antônio Ricardo C. F. Andrade, Liliana S. C. Mendes, Francisco G. C. Penna, Marcelo C. Silva, Frederico C. Salomão, Luiz A. R. Freitas   +7 more
doaj   +1 more source

AUTOIMMUNE PANCREATITIS AND IGG4-ASSOCIATED CHOLANGIOPATHIES (review)

Кубанский научный медицинский вестник, 2018
The article discusses diagnostics and differential diagnosis of chronic autoimmune pancreatitis combined with IgG - associated cholangiopathies, including with lesions of other organs, as in IgG4-systemic ...
Yu. S. Kokarev
doaj   +1 more source

Abcb4 Haploinsufficiency Sensitises Mice to a Diet‐Induced PSC‐Like Hepatobiliary Phenotype With Gallstone Formation

Liver International Communications, Volume 7, Issue 2, June 2026.
ABSTRACT ABCB4 translocates phospholipids (PL) into bile to buffer the toxicity of bile acids (BA) and free cholesterol (CHOL). While recessively inherited ABCB4 deficiency causes childhood Progressive Familial Intrahepatic Cholestasis type 3, haploinsufficiency has been linked to adult‐onset hepatobiliary diseases.
Eric L. Bell, Youhwa Jo, Jennifer K. Truong, Nathan O. Fuller, John P. Miller, Alastair S. Garfield, Robert O. Hughes   +6 more
wiley   +1 more source

A young patient with biliary and urinary disease: What's the unifying diagnosis?

Hong Kong Journal of Emergency Medicine
Introduction Chronic ketamine abuse is a growing public health concern associated with severe organ damage. While ketamine‐induced uropathy and cholangiopathy are well‐documented complications individually, their simultaneous presentation is rare.
Chung‐Wai Wong, Ho‐Nam Ho
doaj   +1 more source

Metformin as a Multifaceted Therapeutic Agent for Gastrointestinal Diseases: Mechanisms, Clinical Efficacy, and Future Directions

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT The high prevalence of gastrointestinal (GI) diseases and their significant impact on the quality of life require new therapeutic strategies. The development of novel therapeutic strategies should prioritize targeting the fundamental pathophysiological mechanisms underlying these diseases, including inflammation, cellular proliferation, and ...
Sayedeh Azimeh Hosseini, Hassan Valadbeigi, Seyedeh Mahdieh Khoshnazar, Saeed Khoshnood, Shahab Falahi, Delsuz Rezaee, Ali Hematian, Mohammad Hossein Haddadi   +7 more
wiley   +1 more source

Review Article: Targeting Peroxisome Proliferator‐Activated Receptors in Primary Biliary Cholangitis

Alimentary Pharmacology &Therapeutics, Volume 63, Issue 9, Page 1215-1235, May 2026.
Peroxisome proliferator‐activated receptor (PPAR) agonists have emerged as important second‐line treatments in primary biliary cholangitis, with profiles influenced by different selectivity for α‐, δ‐ and γ‐isoforms. PPAR‐α and PPAR‐δ agonism improve cholestasis, with inflammation reduced via all isoforms. PPAR‐δ agonism also reduces pruritus.
Jörn M. Schattenberg, Jesus M. Banales, Gideon Hirschfield, Palak Trivedi, Edward E. Cable, Charles A. McWherter, Andrew N. Billin, Daria B. Crittenden, Grant Budas   +8 more
wiley   +1 more source

Varied presentation of celiac disease in Pakistani adults [PDF]

, 2013
he objective of this retrospective study was to evaluate presentation of celiac disease in adults. It included 77 patients, 41 (53.2%) males with median age 26 years and median body mass index of 18 (16 â 22) kg/m2.
Abbas, Zaigham, Abid, Shahab, Hamid, Saeed, Jafri, Wasim, Raza, Sajjad, Shah, Hasnain, Yakoob, Javed   +6 more
core   +1 more source

Embolization of Cyanoacrylate glue in systemic circulation in a case of hepatocellular carcinoma: an autopsy report [PDF]

, 2009
We report a case of embolism of the sclerosant dye with subsequent formation of foreign-body giant cell reaction within the veins of pulmonary and portal circulation in an autopsy case of hepatocellular carcinoma developing over an underlying primary ...
Kochhar Rakesh K, Dutta Usha, Vasishta Rakesh K, Gupta Kirti, Singh Kartar   +4 more
core   +2 more sources

Cholangiopathy as part of post-COVID syndrome

Journal of Translational Autoimmunity, 2021
Liver compromise in critically ill patients with coronavirus disease 2019 (COVID-19) is common but usually transient and self-limited. However, liver tests on some patients continue to show abnormal results.
Manuel Rojas, Yhojan Rodríguez, Elizabeth Zapata, Juan Carlos Hernández, Juan-Manuel Anaya   +4 more
doaj   +1 more source

Proteomic Trajectories of Metabolic and Proteostatic Adaptation During Normothermic Liver Perfusion

Liver International, Volume 46, Issue 5, May 2026.
ABSTRACT Background Normothermic machine perfusion (NMP) enables metabolic restoration and viability testing of liver grafts, but current viability criteria incompletely predict post‐transplant outcomes. The molecular basis of graft resilience or biliary vulnerability remains unclear. This study aimed to characterise tissue‐level proteomic trajectories
Heithem Jeddou, Anne‐Aurélie Raymond, Jean‐William Dupuy, Cyril Dourthe, Hector Prudhomme, Eya Ben Nejma, Stylianos Tzedakis, Bruno Turlin, Pierre Allaume, Karim Boudjema, Michel Samson   +10 more
wiley   +1 more source