Results 51 to 60 of about 3,820 (178)
Clinical Transplantation, Volume 40, Issue 8, August 2026.ABSTRACT Introduction As normothermic machine perfusion (NMP) maintains liver grafts in a near‐physiologic state, uncoupling ischemia–reperfusion injury from the recipient, the validity of early graft dysfunction scores from the static cold storage (SCS) era are uncertain.
Kejal Shah +15 more
wiley +1 more source
A 3D In Vitro Model of the Human Hepatobiliary Junction
Advanced Science, Volume 13, Issue 39, 13 July 2026.A 3D human organoid platform reconstructs the hepatobiliary junction between primary adult hepatocytes and intrahepatic cholangiocytes. These adult hepatobiliary organoids (aHBOs) support directional bile transport from canaliculi to ductule‐like structures, enable quantitative imaging of junction dynamics, and reveal cell‐type‐specific vulnerabilities
Ashley D. Westerfield +13 more
wiley +1 more source
Transplant InternationalBiliary complications are still a major cause for morbidity and mortality after liver transplantation (LT). Ischemia/reperfusion injury (IRI) leads to disruption of the biliary epithelium.
P. Kreiner +10 more
doaj +1 more source
Ischemia–Reperfusion Injury: Molecular Mechanisms and Therapeutic Interventions
MedComm, Volume 7, Issue 7, July 2026.Multiorgan ischemia–reperfusion injury begins with ischemia‐induced ATP depletion and ionic imbalance, followed by reperfusion‐triggered mitochondrial ROS/RNS bursts, regulated cell death, and DAMP release. Sterile inflammation converges on endothelial–immune–coagulation crosstalk, where NETs drive immunothrombosis, no‐reflow, and remote organ injury ...
Peng An +4 more
wiley +1 more source
Biobanked Liver Organoids: A Roadmap for Precision Hepatology
BioEssays, Volume 48, Issue 6, June 2026.Cryopreservation‐enabled biobanking transforms archived human liver tissue into standardized, quality‐controlled organoid resources. By decoupling organoid generation from the availability of fresh tissue, this infrastructure enables scalable, reproducible, and clinically actionable liver models that support precision hepatology, drug development, and ...
Elisa J. Cabré +5 more
wiley +1 more source
International Medical Case Reports Journal, 2023 Abdu Mohammed,1 Abate Bane Shewaye,1,2 Fozia Abdela,1,2 Zebeaman Tibebu Gorfu,1 Ahmed Adem1,2 1Department of Internal Medicine, Adera Medical Center, Addis Ababa, Ethiopia; 2Department of internal Medicine, Addis Ababa University, College of Health ...
Mohammed A +4 more
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Outcomes in Patients with Liver Dysfunction Post SARS-CoV-2 Infection: What Should We Measure?
Hepatic Medicine: Evidence and Research, 2023 Nimy John,1 Brittney Ibrahim,2 Mark Ebaid,2 Sammy Saab1,2 1Department of Medicine, University of California, Los Angeles, CA, USA; 2Department of Surgery, University of California, Los Angeles, CA, USACorrespondence: Sammy Saab, Departments of Medicine ...
John N, Ibrahim B, Ebaid M, Saab S
doaj
COVID-19-Associated Liver Injury
Hepatic Medicine: Evidence and Research, 2023 Daniel T Gildea,1 Stephanie M Woo,2 Corinne E O’Connor,3 Amol S Rangnekar4 1Department of Internal Medicine, MedStar Georgetown University Hospital, Washington, DC, USA; 2Department of Gastroenterology, MedStar Georgetown University Hospital, Washington,
Gildea DT +3 more
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AIDS Cholangiopathy – Diagnostic imaging features
Indian Journal of Community and Family Medicine, 2017 It is important to emphasize that the presence of intrahepatic or extrahepatic biliary stenotic foci in an HIV-positive patient with low CD4 count suggests a possibility of AIDS-associated cholangiopathy, which may be an indicator of progression of the ...
Vandana V Ahluwalia +3 more
doaj +1 more source
Frontiers in Cell and Developmental BiologyIdiopathic cholangiopathies are diseases that affect cholangiocytes, and they have unknown etiologies. Currently, orthotopic liver transplantation is the only treatment available for end-stage liver disease.
Nova Yuli Prasetyo Budi +12 more
doaj +1 more source