Results 41 to 50 of about 3,820 (178)

Effects of post‐hepatic portoenterostomy adjuvant therapy on liver transplantation in children with biliary atresia: A systematic review

open access: yesJPGN Reports, EarlyView.
Abstract Objectives Biliary atresia (BA) is a cholangiopathy characterized by obstruction of the intrahepatic and extrahepatic bile ducts. Hepatic portoenterostomy (HPE) is the primary palliative treatment and there is still an urgent need to improve post‐HPE management.
Bianca Ferraz de Almeida Silva   +7 more
wiley   +1 more source

AUTOIMMUNE PANCREATITIS AND IGG4-ASSOCIATED CHOLANGIOPATHIES (review)

open access: yesКубанский научный медицинский вестник, 2018
The article discusses diagnostics and differential diagnosis of chronic autoimmune pancreatitis combined with IgG - associated cholangiopathies, including with lesions of other organs, as in IgG4-systemic ...
Yu. S. Kokarev
doaj   +1 more source

A young patient with biliary and urinary disease: What's the unifying diagnosis?

open access: yesHong Kong Journal of Emergency Medicine
Introduction Chronic ketamine abuse is a growing public health concern associated with severe organ damage. While ketamine‐induced uropathy and cholangiopathy are well‐documented complications individually, their simultaneous presentation is rare.
Chung‐Wai Wong, Ho‐Nam Ho
doaj   +1 more source

Current Cell/Organoid and Animal Models for Primary Sclerosing Cholangitis

open access: yesPortal Hypertension &Cirrhosis, EarlyView.
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease with limited therapeutic options and a marked risk of progression to biliary fibrosis, cirrhosis, and malignancy. Progress in PSC research has been hindered by the lack of models that faithfully recapitulate the complex biliary microenvironment and disease heterogeneity ...
Qigu Yao   +4 more
wiley   +1 more source

When Machine Perfusion Falls Short: Identifying Risks of Liver Graft Failure After Normothermic Machine Perfusion

open access: yesArtificial Organs, EarlyView.
Analysis of 4928 normothermic machine perfusion liver transplants reveals that recipient factors, particularly MELD ≥ 35, surgical complexity, ICU status, and functional impairment are stronger predictors of graft failure than donor characteristics, emphasizing the continued importance of clinical judgment in patient selection.
Lauren E. Matevish   +9 more
wiley   +1 more source

Liver Organoids: From Disease Modelling to Regenerative Medicine

open access: yesCell Proliferation, EarlyView.
Liver organoids provide a versatile platform for disease modelling and drug discovery, leveraging stem cells and engineering techniques. They bridge research and clinical applications, offering significant potential for advancing precision medicine and regenerative therapies for liver diseases.
Tiepeng Wang   +5 more
wiley   +1 more source

Histological AI‐Assisted Analysis Outperforms Pathologist Assessment in Predicting Disease Outcomes in PSC Patients

open access: yesHepatology Research, EarlyView.
Analyzing liver histology with AI assistance demonstrates superior prognostic performance compared to manual scoring in PSC. AI‐measured portal inflammation, fibrosis, biliary epithelium, and blood vessels predicted key clinical endpoints, such as liver transplantation due to end‐stage liver disease, highlighting the importance of liver histology as a ...
Anna M. Salonen   +9 more
wiley   +1 more source

Effects of Melittin Treatment in Cholangitis and Biliary Fibrosis in a Model of Xenobiotic-Induced Cholestasis in Mice

open access: yesToxins, 2015
Cholangiopathy is a chronic immune-mediated disease of the liver, which is characterized by cholangitis, ductular reaction and biliary-type hepatic fibrosis. There is no proven medical therapy that changes the course of the disease.
Kyung-Hyun Kim   +7 more
doaj   +1 more source

Indoleamine 2,3‐Dioxygenase 1 as an Adjunctive Histopathological Marker of Cholangitis Activity in Primary Biliary Cholangitis

open access: yesHepatology Research, EarlyView.
IDO‐1 immunostaining identifies primary biliary cholangitis even in morphologically subtle bile duct lesions. IDO‐1 expression reflects cholangitis activity and is suppressed by ursodeoxycholic acid treatment, indicating its value as a dynamic diagnostic adjunct rather than a static marker of chronic damage.
Kaori Yoshimura   +10 more
wiley   +1 more source

Imaging of Benign Biliary Tract Disease

open access: yesIndian Journal of Radiology and Imaging
This review article discusses the most common benign biliary disorders and the various radiological findings on multiple modalities. A broad spectrum of diseases including various congenital disorders, infective and parasitic etiologies, immunological ...
Samarjit Singh Ghuman   +5 more
doaj   +1 more source

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