Results 21 to 30 of about 3,820 (178)

Secondary Sclerosing Cholangitis After SARS-CoV2: ICU Ketamine Use or Virus-Specific Biliary Tropism and Injury in the Context of Biliary Ischemia in Critically Ill Patients?

Hepatic Medicine: Evidence and Research, 2023
Alessandra Bartoli,1,2 Carmela Cursaro,1 Hajrie Seferi,1 Pietro Andreone3,4 1Division of Internal Medicine and Metabolism, Department of Internal Medicine, Ospedale Civile di Baggiovara, University of Modena and Reggio Emilia, Modena, Italy; 2Post ...
Bartoli A, Cursaro C, Seferi H, Andreone P   +3 more
doaj  

Diagnostic Impact of Liver Biopsy Among Antinuclear Antibody Positive Individuals With Mild Liver Enzyme Elevation. [PDF]

Aliment Pharmacol Ther
In ANA‐positive patients with suspected autoimmune hepatitis (AIH), liver biopsy rarely altered therapeutic management when alanine aminotransferase (ALT) was below 101 U/L and cirrhosis was absent. These findings suggest that biopsy may be safely deferred in this low‐risk group.
Niazi DMA, Charbel A, Pfeiffenberger J, Merle U, Seessle J, Wenz T, Flechtenmacher C, Michl P, Rauber C.   +8 more
europepmc   +2 more sources

Primary Biliary Cholangitis and Primary Sclerosing Cholangitis: Current Knowledge of Pathogenesis and Therapeutics

Biomedicines, 2022
Cholangiopathies encompass various biliary diseases affecting the biliary epithelium, resulting in cholestasis, inflammation, fibrosis, and ultimately liver cirrhosis.
Ji-Won Park, Jung-Hee Kim, Sung-Eun Kim, Jang Han Jung, Myoung-Kuk Jang, Sang-Hoon Park, Myung-Seok Lee, Hyoung-Su Kim, Ki Tae Suk, Dong Joon Kim   +9 more
doaj   +1 more source

Biology of Cholangiocytes: From Bench to Bedside

Gut and Liver, 2016
Cholangiocytes, the lining epithelial cells in bile ducts, are an important subset of liver cells. They are activated by endogenous and exogenous stimuli and are involved in the modification of bile volume and composition.
Kyo-Sang Yoo, Woo Taek Lim, Ho Soon Choi
doaj   +1 more source

Clinical and Histopathological Discoveries in Patients with Hepatic Injury and Cholangiopathy Who Have Died of COVID-19: Insights and Opportunities for Intervention

Hepatic Medicine: Evidence and Research, 2023
Joseph K Lim, Basile Njei Yale Liver Center and Section of Digestive Diseases, Yale University School of Medicine, New Haven, CT, USACorrespondence: Joseph K Lim, Yale Liver Center and Section of Digestive Diseases, Yale University School of Medicine ...
Lim JK, Njei B
doaj  

Portal Cavernoma Cholangiopathy [PDF]

Current Hepatology Reports, 2014
Portal cavernoma cholangiopathy is a rare condition, a proper recognition of which is critical. Solid data on this condition are scarce. This review aims at updating current knowledge on its definition, manifestations, diagnosis, and management. A consensus has been reached to prefer the denomination portal cavernoma cholangiopathy for the bile duct ...
openaire   +3 more sources

Distinct EpCAM-Positive Stem Cell Niches Are Engaged in Chronic and Neoplastic Liver Diseases

Frontiers in Medicine, 2020
In normal human livers, EpCAMpos cells are mostly restricted in two distinct niches, which are (i) the bile ductules and (ii) the mucous glands present inside the wall of large intrahepatic bile ducts (the so-called peribiliary glands).
Samira Safarikia, Guido Carpino, Diletta Overi, Vincenzo Cardinale, Rosanna Venere, Antonio Franchitto, Paolo Onori, Domenico Alvaro, Eugenio Gaudio   +8 more
doaj   +1 more source

Crystal-associated cholangiopathy in sheep grazing Brachiaria decumbens containing the saponin protodioscin Colangiopatia associada a cristais em ovinos alimentados com Brachiaria decumbens que contém a saponina protodioscina

Pesquisa Veterinária Brasileira, 2007
An outbreak of hepatogenous photosensitization is reported in a flock of 28 sheep grazing Brachiaria decumbens in Mato Grosso do Sul State, Central-Western Brazil. Seven lambs and an adult sheep were affected and 6 of them died.
Karine B. Brum, Mitsue Haraguchi, Ricardo A.A. Lemos, Franklin Riet-Correa, Maria Clorinda S. Fioravanti   +4 more
doaj   +1 more source

Diet‐Induced Dysbiosis and Genetic Background Synergize With Cystic Fibrosis Transmembrane Conductance Regulator Deficiency to Promote Cholangiopathy in Mice

Hepatology Communications, 2018
The most typical expression of cystic fibrosis (CF)–related liver disease is a cholangiopathy that can progress to cirrhosis. We aimed to determine the potential impact of environmental and genetic factors on the development of CF‐related cholangiopathy ...
Dominique Debray, Haquima El Mourabit, Fatiha Merabtene, Loïc Brot, Damien Ulveling, Yves Chrétien, Dominique Rainteau, Ivan Moszer, Dominique Wendum, Harry Sokol, Chantal Housset   +10 more
doaj   +1 more source

Galectin-3 and prohibitin 1 are autoantigens in IgG4-related cholangitis without clear-cut protective effects against toxic bile acids

Frontiers in Immunology
Background and aimsIgG4-related cholangitis (IRC) is the hepatobiliary manifestation of IgG4-related disease, a systemic B cell-driven fibro-inflammatory disorder.
Remco Kersten, David C. Trampert, Lowiek M. Hubers, Dagmar Tolenaars, Harmjan R. Vos, Stan F. J. van de Graaf, Ulrich Beuers   +6 more
doaj   +1 more source