Results 11 to 20 of about 6,798 (251)
International Journal of Hepatology, 2012 IgG4 cholangiopathy can involve any level of the biliary tree which exhibits sclerosing cholangitis or pseudotumorous hilar lesions. Most cases are associated with autoimmune pancreatitis, an important diagnostic clue.
Yoh Zen, Yasuni Nakanuma
doaj +4 more sources
Biology of Cholangiocytes: From Bench to Bedside [PDF]
Gut and Liver, 2016 Cholangiocytes, the lining epithelial cells in bile ducts, are an important subset of liver cells. They are activated by endogenous and exogenous stimuli and are involved in the modification of bile volume and composition.
Kyo-Sang Yoo, Woo Taek Lim, Ho Soon Choi
doaj +3 more sources
Mayo Clinic Proceedings, 2015 Cholangiocytes (ie, the epithelial cells that line the bile ducts) are an important subset of liver cells. They are actively involved in the modification of bile volume and composition, are activated by interactions with endogenous and exogenous stimuli (eg, microorganisms, drugs), and participate in liver injury and repair.
Konstantinos N, Lazaridis +1 more
openaire +2 more sources
Biliary Glutathione as a Potential Marker for Viability Assessment of Cholangiocytes During Normothermic Machine Perfusion of Livers. [PDF]
Artif OrgansThis study identifies biliary glutathione concentration during normothermic machine perfusion as a potential biomarker for biliary viability. Increasing GSH levels correlate with fewer biliary complications post‐transplant, supporting its role in assessing graft quality and improving decision‐making in liver transplantation.
Bogensperger C +10 more
europepmc +2 more sources
Liver Transplantation, EarlyView., 2022 Abstract End‐ischemic viability testing by normothermic machine perfusion (NMP) represents an effective strategy to recover liver grafts having initially been discarded for liver transplantation (LT). However, its results in the setting of significant (≥30%) macrovesicular steatosis (MaS) have not been specifically assessed.
Damiano Patrono +8 more
wiley +1 more source
The natural history of primary sclerosing cholangitis in 781 children. A multicenter, international collaboration [PDF]
, 2017 There are limited data on the natural history of primary sclerosing cholangitis (PSC) in children. We aimed to describe the disease characteristics and long-term outcomes of pediatric PSC.
Abdou, Reham +45 more
core +6 more sources
Journal of Lipid Research, 2023 Therapeutic reduction of hydrophobic bile acids exposure is considered beneficial in cholestasis. The Cyp2c70 KO mice lack hydrophilic muricholic acids and have a human-like hydrophobic bile acid pool resulting in hepatobiliary injury.
Mohammad Nazmul Hasan +8 more
doaj +1 more source
MicroRNAs in Cholangiopathies [PDF]
Current Pathobiology Reports, 2014 Cholangiocytes, the cells lining bile ducts, comprise a small fraction of the total cellular component of the liver, yet perform the essential role of bile modification and transport of biliary and blood constituents. Cholangiopathies are a diverse group of biliary disorders with the cholangiocyte as the target cell; the etiopathogenesis of most ...
Steven P, O'Hara +4 more
openaire +2 more sources
Reversine attenuates cholestatic ductular reaction in rats
FEBS Open Bio, 2023 Ductular reaction (DR) is usually observed in biliary disorders or various liver disorders, including nonalcoholic fatty liver disease. Few studies have focused on interrupting the DR process in the cholestatic environment.
Di Huang +8 more
doaj +1 more source
CAQ Corner: Immune‐mediated complications
, 2022 Liver Transplantation, EarlyView.
Mary Thomson, John R. Lake
wiley +1 more source