Results 31 to 40 of about 6,798 (251)

Observations on the ex situ perfusion of livers for transplantation. [PDF]

, 2018
Normothermic ex situ liver perfusion might allow viability assessment of livers before transplantation. Perfusion characteristics were studied in 47 liver perfusions, of which 22 resulted in transplants.
Allison, Michael, Brais, Rebecca, Butler, Andrew J, Crick, Keziah, Fear, Corinna, Gimson, Alexander E, Jochmans, Ina, Kosmoliaptsis, Vasilis, Pley, Caitlin, Randle, Lucy, Upponi, Sara, Watson, Christopher JE   +11 more
core   +1 more source

Secondary Sclerosing Cholangitis After SARS-CoV2: ICU Ketamine Use or Virus-Specific Biliary Tropism and Injury in the Context of Biliary Ischemia in Critically Ill Patients?

Hepatic Medicine: Evidence and Research, 2023
Alessandra Bartoli,1,2 Carmela Cursaro,1 Hajrie Seferi,1 Pietro Andreone3,4 1Division of Internal Medicine and Metabolism, Department of Internal Medicine, Ospedale Civile di Baggiovara, University of Modena and Reggio Emilia, Modena, Italy; 2Post ...
Bartoli A, Cursaro C, Seferi H, Andreone P   +3 more
doaj  

Recapitulating Cholangiopathy-Associated Necroptotic Cell Death In Vitro Using Human Cholangiocyte OrganoidsSummary

Cellular and Molecular Gastroenterology and Hepatology, 2022
Background & Aims: Liver and bile duct diseases often are associated with extensive cell death of cholangiocytes. Necroptosis represents a common mode of programmed cell death in cholangiopathy, however, detailed mechanistic knowledge is limited ...
Shaojun Shi, Monique M.A. Verstegen, Henk P. Roest, Arif I. Ardisasmita, Wanlu Cao, Floris J.M. Roos, Petra E. de Ruiter, Marije Niemeijer, Qiuwei Pan, Jan N.M. IJzermans, Luc J.W. van der Laan   +10 more
doaj   +1 more source

Identification of PKD1L1 Gene Variants in Children with the Biliary Atresia Splenic Malformation Syndrome [PDF]

, 2019
Biliary atresia (BA) is the most common cause of end‐stage liver disease in children and the primary indication for pediatric liver transplantation, yet underlying etiologies remain unknown.
Alonso, Estella M, Berauer, John‐Paul, Bezerra, Jorge A, Bull, Laura N, Chopra, Pankaj, Cutler, David J, Finegold, Milton J, Gibbs, Richard A, Guthery, Stephen L, Harpavat, Sanjiv, Hegde, Madhuri R, Kamath, Binita M, Karpen, Saul J, Loomes, Kathleen M, Magee, John C, Mezina, Anya I, Molleston, Jean P, Moore, Barry, Murray, Karen F, Muzny, Donna M, Network, for the Childhood Liver Disease Research, Okou, David T, Perlmutter, David H, Rajagopalan, Ramakrishnan, Rosenthal, Philip, Russo, Pierre, Sabo, Aniko, Sherker, Averell H, Sokol, Ronald J, Spinner, Nancy B, Squires, Robert H, Thompson, Richard J, Wang, Kasper S, Yandell, Mark   +33 more
core   +2 more sources

Portal Cavernoma Cholangiopathy [PDF]

Current Hepatology Reports, 2014
Portal cavernoma cholangiopathy is a rare condition, a proper recognition of which is critical. Solid data on this condition are scarce. This review aims at updating current knowledge on its definition, manifestations, diagnosis, and management. A consensus has been reached to prefer the denomination portal cavernoma cholangiopathy for the bile duct ...
openaire   +3 more sources

Ischemic Cholangiopathy 11 Years after Liver Transplantation from Asymptomatic Chronic Hepatic Artery Thrombosis [PDF]

, 2018
Hepatic artery thrombosis is a concerning complication of orthotopic liver transplantation, and it most often occurs early in the posttransplant period. However, on rare occasions it can occur at a time remote from transplant.
Johnson, Matthew S., Krajicek, Edward, Lacerda, Marco, Sherman, Stuart, Vuppalanchi, Raj   +4 more
core   +1 more source

Challenges in machine perfusion preservation for liver grafts from donation after circulatory death [PDF]

, 2013
Donation after circulatory death (DCD) is a promising solution to the critical shortage of donor graft tissue. Maintaining organ viability after donation until transplantation is essential for optimal graft function and survival.
Eiji Kobayashi, Naoto Matsuno
core   +1 more source

Clinical and Histopathological Discoveries in Patients with Hepatic Injury and Cholangiopathy Who Have Died of COVID-19: Insights and Opportunities for Intervention

Hepatic Medicine: Evidence and Research, 2023
Joseph K Lim, Basile Njei Yale Liver Center and Section of Digestive Diseases, Yale University School of Medicine, New Haven, CT, USACorrespondence: Joseph K Lim, Yale Liver Center and Section of Digestive Diseases, Yale University School of Medicine ...
Lim JK, Njei B
doaj  

Distinct EpCAM-Positive Stem Cell Niches Are Engaged in Chronic and Neoplastic Liver Diseases

Frontiers in Medicine, 2020
In normal human livers, EpCAMpos cells are mostly restricted in two distinct niches, which are (i) the bile ductules and (ii) the mucous glands present inside the wall of large intrahepatic bile ducts (the so-called peribiliary glands).
Samira Safarikia, Guido Carpino, Diletta Overi, Vincenzo Cardinale, Rosanna Venere, Antonio Franchitto, Paolo Onori, Domenico Alvaro, Eugenio Gaudio   +8 more
doaj   +1 more source

Primary Biliary Cholangitis and Primary Sclerosing Cholangitis: Current Knowledge of Pathogenesis and Therapeutics

Biomedicines, 2022
Cholangiopathies encompass various biliary diseases affecting the biliary epithelium, resulting in cholestasis, inflammation, fibrosis, and ultimately liver cirrhosis.
Ji-Won Park, Jung-Hee Kim, Sung-Eun Kim, Jang Han Jung, Myoung-Kuk Jang, Sang-Hoon Park, Myung-Seok Lee, Hyoung-Su Kim, Ki Tae Suk, Dong Joon Kim   +9 more
doaj   +1 more source