Results 111 to 120 of about 50,002 (295)

Genetic Determination of Plasma Cholesterol Efflux Capacity Is Gender-Specific and Independent of HDL-Cholesterol Levels

, 2013
International audienceObjective— We investigated the impact of several genetic variants located in genes encoding for proteins involved in biogenesis, maturation, and intravascular remodeling of high density lipoprotein (HDL) particles on plasma efflux ...
Bonnefont-Rousselot, Dominique, M. Guerin, Le Goff, Wilfried, P. EI Khoury, Guerin, Maryse, Ei Khoury, Petra, Bittar, Randa, D. Bonnefont-Rousselot, Clement, Karine, E. Frisdal, E. Bruckert, Frisdal, Eric, W. Le Goff, K. Clement, Bruckert, Eric, R. Bittar, Villard, Elise, E. F. Villard   +17 more
core   +1 more source

Expression of caveolin-1 enhances cholesterol efflux in hepatic cells [PDF]

, 2004
HepG2 cells were stably transfected with human caveolin-1 (HepG2/cav cells). Transfection resulted in expression of caveolin-1 mRNA, a high abundance of caveolin-1 protein, and the formation of caveolae on the plasma membrane.
Fu, Y., Krozowski, Z., Escher, G., Parton, R. G., Hoang, A., Sviridov, D.   +5 more
core   +1 more source

Serum albumin acts as a shuttle to enhance cholesterol efflux from cells[S]

Journal of Lipid Research, 2013
An important mechanism contributing to cell cholesterol efflux is aqueous transfer in which cholesterol diffuses from cells into the aqueous phase and becomes incorporated into an acceptor particle.
Sandhya Sankaranarayanan, Margarita de la Llera-Moya, Denise Drazul-Schrader, Michael C. Phillips, Ginny Kellner-Weibel, George H. Rothblat   +5 more
doaj   +1 more source

Plasma cholesterol efflux capacity from human THP-1 macrophages is reduced in HIV-infected patients: impact of HAART[S]

Journal of Lipid Research, 2015
The capacity of HDL to remove cholesterol from macrophages is inversely associated with the severity of angiographic coronary artery disease. The effect of human immunodeficiency virus (HIV) infection or its treatment on the ability of HDL particles to ...
Petra El Khoury, Mathilde Ghislain, Elise F. Villard, Wilfried Le Goff, Caroline Lascoux-Combe, Patrick Yeni, Laurence Meyer, Corinne Vigouroux, Cécile Goujard, Maryse Guerin   +9 more
doaj   +1 more source

The role of cholesterol efflux in macrophage cholesterol homeostasis

, 2005
The development of atherosclerosis can be influenced by genetic or pharmacologic disruptions of cellular cholesterol homeostasis. Cholesterol homeostasis in macrophages is of critical importance because these cells have a pivotal function in the vessel ...
Dove, Dwayne E.
core  

A critical reappraisal of the carotid sinus and carotid bulb: Distinguishing neurohistological function from vascular geometry

The Anatomical Record, EarlyView.
This review redefines the carotid bulb (CB) as a variable geometric dilation shaped by hemodynamics and the carotid sinus (CS) as a conserved neurohistological baroreceptor field. Distinguishing these entities clarifies a century of anatomical confusion and links geometry, neurohistology, and clinical interpretation within a unified framework ...
Răzvan Costin Tudose, Nicolae Radu, Mugurel Constantin Rusu   +2 more
wiley   +1 more source

Cholesterol efflux capacity of HDL fractions from ApoF KO mice.

, 2012
Serum was collected from wild type and ApoF KO mice for the measurement of cholesterol efflux capacity.. Apo B lipoproteins were precipitated with polyethylene glycol, and the resulting supernatant (containing HDL and other soluble serum proteins) was ...
Sumeet A. Khetarpal (182252), George H. Rothblat (182272), Denise Drazul-Schrader (182268), Sarah F. Hamm-Alvarez (182267), Daniel J. Rader (113673), Wen Lin (36325), William R. Lagor (182248), Arthi Kumaravel (182255), Kaijin Wu (182262), David W. Fields (182249), Margarita de la Llera-Moya (182270), Nathaniel Weintraub (182258)   +11 more
core   +1 more source

Dual Functions of Dietary Rubber Seed Oil Supplementation: Enriching N‐3 Polyunsaturated Fatty Acids and Enhancing Antioxidant Capacity in Pekin Ducks

Animal Research and One Health, EarlyView.
Dietary RSO supplementation improved growth performance, simultaneously enriched n‐3 polyunsaturated fatty acids (n‐3 PUFA), and enhanced antioxidant capacity in Pekin ducks, which suggested that RSO has the potential to be a novel n‐3 PUFA source and an antioxidant for Pekin ducks to generate animal functional foods.
Lei Zhuang, Yongbao Wu, Zitao Zhao, Junting Cao, Yanhong Guo, Zhanyue Wu, Qimeng Wang, Peilong Yang, Sen Wu, Zhiguo Wen, Shuisheng Hou   +10 more
wiley   +1 more source

Serum, but not monocyte macrophage foam cells derived from low HDL-C subjects, displays reduced cholesterol efflux capacity

Journal of Lipid Research, 2009
The main antiatherogenic function of HDL is to promote the efflux of cholesterol from peripheral cells and transport it to the liver for excretion in a process termed reverse cholesterol transport.
Shuhei Nakanishi, Riikka Vikstedt, Sanni Söderlund, Miriam Lee-Rueckert, Anne Hiukka, Christian Ehnholm, Mikko Muilu, Jari Metso, Jussi Naukkarinen, Leena Palotie, Petri T. Kovanen, Matti Jauhiainen, Marja-Riitta Taskinen   +12 more
doaj   +1 more source

Nanomaterial‐based immune therapeutic strategies in neurodegenerative diseases

BMEMat, EarlyView.
This review highlights the immunomodulatory potential of nanomaterials (NMs) in treating neurodegenerative diseases (NDs). It focuses on their roles in regulating innate and adaptive immune responses to maintain immune homeostasis. By providing insights into these mechanisms, the review lays the groundwork for innovative NMs therapeutic strategies to ...
Xinru Zhou, Jia Liu, Shulin Lai, Suhan Yin, Bingmin Luo, Longquan Shao, Yiyuan Kang   +6 more
wiley   +1 more source