Results 121 to 130 of about 24,401 (257)

Immunomodulatory and Cytotoxic Properties of Enniatin B1 in Porcine Alveolar Macrophages

Journal of Applied Toxicology, EarlyView.
ABSTRACT This study investigates the immunomodulatory effects of Enniatin B1 (ENNB1), an emerging mycotoxin, on porcine alveolar macrophages (PAMs), a species‐specific model relevant to human innate immunity. PAMs were exposed to increasing ENNB1 concentrations (0.5–6 μM) over 6, 24, and 48 h.
Sara Frazzini, Francesca Caloni, Paola Fossati, Giancarlo Ruffo, Luciana Rossi   +4 more
wiley   +1 more source

Postprandial lipemia enhances the capacity of large HDL2 particles to mediate free cholesterol efflux via SR-BI and ABCG1 pathways in type IIB hyperlipidemia[S]

Journal of Lipid Research, 2010
Lipid and cholesterol metabolism in the postprandial phase is associated with both quantitative and qualitative remodeling of HDL particle subspecies that may influence their anti-atherogenic functions in the reverse cholesterol transport pathway.
Zélie Julia, Emilie Duchene, Natalie Fournier, Natacha Bellanger, M. John Chapman, Wilfried Le Goff, Maryse Guerin   +6 more
doaj   +1 more source

Salt‐induced nutritional and metabolic shifts in halophytes: implications for food security

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Plant species vary in their response to salinity: some crops show a degree of salt tolerance, while halophytes – whether wild or cultivated – are characterized by a high capacity to thrive under saline conditions. Halophytes are considered a source of valuable secondary metabolites with potential economic value, yet they might also produce ...
Giulia Atzori, Pedro Garcia Caparros, Antonella Castagna, Luisa Custódio, Valentina Lazazzara, Claus Krogh Madsen, Felicia Menicucci, Maria João Rodrigues, Katalin Solymosi, Jose Ramon Acosta Motos   +9 more
wiley   +1 more source

Association of HDL cholesterol efflux capacity with incident coronary heart disease events: a prospective case-control study

, 2015
SummaryBackgroundAlthough HDL cholesterol concentrations are strongly and inversely associated with risk of coronary heart disease, interventions that raise HDL cholesterol do not reduce risk of coronary heart disease.
Zhao, Wei, Lukmanova, Daniya, Wareham, Nick, Scott, Robert, Saleheen, Danish, Javad, Sundas, Rader, Daniel J, Rader, Daniel J., Billheimer, Jeffery, Boekholdt, S. Matthijs, Luben, Robert, Rodrigues, Amrith, Mucksavage, Megan L, Khaw, Kay-Tee, Picataggi, Antonino, Boekholdt, S Matthijs, Kastelein, John J P, Mucksavage, Megan L., Kastelein, John J. P.   +18 more
core   +1 more source

Metabolic Dysfunction‐Associated Steatotic Liver Disease and Obesity: Pathogenesis, Diagnostics, Risk Stratification, and Therapeutic Approach

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) has emerged as the most prevalent chronic liver disease worldwide, closely linked to the global rising incidence of obesity and metabolic syndrome. This review synthesizes current evidence on the pathogenesis, gut–liver axis, and multidisciplinary management of MASLD within the ...
Beom Kyung Kim
wiley   +1 more source

The Role of Obesity in the Association Between Alcohol Consumption and HDL‐c Levels: Baependi Heart Study

Lipids, EarlyView.
ABSTRACT Cardiovascular diseases (CVD) are a leading cause of global mortality, with dyslipidemia playing a central role in their pathogenesis. The influence of alcohol consumption on lipid profiles, particularly high‐density lipoprotein cholesterol (HDL‐c), in relation to obesity status remains insufficiently explored.
Larissa Esthefani Barros Cirino, Divanei Zaniqueli, Oscar Geovanny Enriquez‐Martinez, Camila Maciel de Oliveira, Alexandre da Costa Pereira, Jordana Herzog Siqueira, Rafael de Oliveira Alvim   +6 more
wiley   +1 more source

Recent Advances in Top‐Down Proteomics for Single‐Cell Research

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Individual cells have distinctive molecular characteristics, including biologically relevant proteoforms. Although single‐cell (SC) molecular omics offer unprecedented insights into cellular heterogeneity and function, the characterization of proteoforms in SCs remains an uncharted territory.
Jake A. Melby, Pei Su, Fabio P. Gomes
wiley   +1 more source

Cholesterol efflux capacity and arterial stiffness in healthy subjects: data from the brisighella heart study

, 2012
Purpose: Serum capacity to promote cholesterol efflux from macrophages correlates inversely with carotid intima–media thickness and the likelihood of angiographic coronary artery disease, independently of the high density lipoprotein (HDL) level.
CICERO, ARRIGO FRANCESCO GIUSEPPE, Adorni M. P., Ronda N., Salvi P., Favari E., Zimetti F, Bernini F., BORGHI, CLAUDIO   +7 more
core  

Pearson correlation of clinical and laboratory variables with HDL AE activity and cholesterol efflux capacity.

, 2016
Pearson correlation of clinical and laboratory variables with HDL AE activity and cholesterol efflux capacity.
Ines Potočnjak (2837801), Matias Trbušić (2837804), Sanda Dokoza Terešak (2837807), Bojana Radulović (2837813), Saša Frank (2837810), Beate Tiran (239387), Gunther Marsche (312903), Vesna Degoricija (2837798), Andrea Berghold (690535), Gudrun Pregartner (690536)   +9 more
core   +1 more source

The Lipid Droplet–Associated Hydrolase Is Associated With Obesity and Adipose Tissue Inflammation in Children

Obesity, EarlyView.
ABSTRACT Objective The lipid droplet–associated hydrolase (LDAH) is a lipid droplet–associated protein with an uncharacterized role in human adipose tissue (AT) and obesity; we aimed to investigate its role in human AT and its relevance for childhood obesity.
Claudia Vales‐Villamarín, Antje Berthold, Martin Lacher, Antje Körner, Kathrin Landgraf   +4 more
wiley   +1 more source