Results 21 to 30 of about 77,225 (214)

Is pesticide exposure a cause of obstructive airways disease? [PDF]

open access: yes, 2014
Peer reviewedPublisher ...
Ayres, Jon G.   +6 more
core   +2 more sources

In Vitro Enzymatic and Kinetic Studies, and In Silico Drug-Receptor Interactions, and Drug-Like Profiling of the 5-Styrylbenzamide Derivatives as Potential Cholinesterase and β-Secretase Inhibitors with Antioxidant Properties

open access: yesAntioxidants, 2021
The 5-(styryl)anthranilamides were transformed into the corresponding 5-styryl-2-(p-tolylsulfonamido)benzamide derivatives. These 5-styrylbenzamide derivatives were evaluated through enzymatic assays in vitro for their capability to inhibit ...
Malose J. Mphahlele   +3 more
doaj   +1 more source

Amyloid Alpha: The Neglected Cousin of Amyloid Beta. [PDF]

open access: yesChembiochem
Amyloid α (Aα), also known as P3, is an alternative processing product of amyloid precursor protein that may be formed instead of Amyloid β (Aβ). Unlike Aβ, Aα/P3 has received little attention and is commonly dismissed as nonamyloidogenic. This perspective article refutes the notion that Aα/P3 is nonamyloidogenic and nontoxic.
Raskatov JA.
europepmc   +2 more sources

Evaluation of Toxic Effects Induced by Sub-Acute Exposure to Low Doses of α-Cypermethrin in Adult Male Rats

open access: yesToxics, 2022
To contribute new information to the pyrethroid pesticide α-cypermethrin toxicity profile, we evaluated its effects after oral administration to Wistar rats at daily doses of 2.186, 0.015, 0.157, and 0.786 mg/kg bw for 28 days. Evaluations were performed
Vilena Kašuba   +9 more
doaj   +1 more source

Adverse Effects of Cholinesterase Inhibitors in Dementia, According to the Pharmacovigilance Databases of the United-States and Canada. [PDF]

open access: yes, 2015
This survey analyzes two national pharmacovigilance databases in order to determine the major adverse reactions observed with the use of cholinesterase inhibitors in dementia.
Abagyan, Ruben   +4 more
core   +3 more sources

Effects of occupational exposure in pesticide plant on workers' serum and erythrocyte cholinesterase activity [PDF]

open access: yes, 2007
Objectives: The determination of cholinesterase activity has been commonly applied in the biomonitoring of exposure to organophosphates and carbamates and in the diagnosis of poisoning with anticholinesterase compounds.
Ahmadi, A.R.   +2 more
core   +1 more source

Changes of Cholinesterase Activity in the Erythrocytes, Plasma, Diaphragm, Liver and Various Parts of the Brain in the Rabbit Following Transfusion of Erythrocytes with Soman Inhibited Acetylcholinesterase

open access: yesActa Medica, 1997
1. The changes of cholinesterase activity in rabbit blood, peripheral tissues and the central nervous system following transfusion of erythrocytes with soman inhibited acetylcholinesterase were demonstrated. 2. After incubation with soman for 0.5 or 24 h,
Jiří Kassa, Jiří Bajgar, Josef Fusek
doaj   +1 more source

The effects of donepezil in Alzheimer's disease - Results from a multinational trial [PDF]

open access: yes, 1999
Donepezil has been shown to be well tolerated and to improve cognition and global function in patients with mild to moderately severe Alzheimer's disease (AD).
Burns, A.   +7 more
core   +1 more source

Plant-Derived Bioactive Compounds in the Management of Neurodegenerative Disorders: Challenges, Future Directions and Molecular Mechanisms Involved in Neuroprotection

open access: yesPharmaceutics, 2023
Neurodegenerative disorders encompass a wide range of pathological conditions caused by progressive damage to the neuronal cells and nervous-system connections, which primarily target neuronal dysfunction and result in problems with mobility, cognition ...
Shoaib Shoaib   +12 more
doaj   +1 more source

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