Results 141 to 150 of about 2,823,581 (316)

Integrating neuroinflammation biomarkers into the ATN(X) framework: Advances in Alzheimer's pathogenesis, diagnosis, and insights from non‐human primate models

open access: yesAlzheimer's &Dementia, Volume 21, Issue 8, August 2025.
Abstract The amyloid/tau/neurodegeneration (ATN) biomarker framework has greatly progressed the diagnosis and staging of Alzheimer's disease (AD). However, recent research highlights neuroinflammation as an equally critical factor in AD pathology across humans, rodents, and non‐human primates (NHPs).
Zhihui Jin   +3 more
wiley   +1 more source

Pneumonia Risk with Cholinesterase Inhibitors [PDF]

open access: yesJournal of the American Geriatrics Society, 2016
Terry Lynn Hughes   +2 more
openaire   +3 more sources

Modernizing diagnosis of Alzheimer's disease: A review of global trends and Asia‐specific perspectives

open access: yesAlzheimer's &Dementia, Volume 21, Issue 8, August 2025.
Abstract The landscape of Alzheimer's disease (AD) and related dementias (ADRD) diagnosis is evolving rapidly, driven by advances in disease understanding, biomarker tools, and disease‐modifying therapies. Modern diagnostic approaches emphasize biological precision, early detection, and dynamic frameworks that adapt to treatment‐induced changes in ...
Takeshi Iwatsubo   +43 more
wiley   +1 more source

A CHOLINESTERASE INHIBITOR PRODUCED BY ASPERGILLUS TERREUS

open access: bronze, 1974
Kôichi Ogata   +3 more
openalex   +2 more sources

Dementia care and mortality in people experiencing homelessness: A matched cohort study

open access: yesAlzheimer's &Dementia, Volume 21, Issue 8, August 2025.
Abstract INTRODUCTION People experiencing homelessness are disproportionately affected by dementia, yet little is known about their dementia care and mortality rates after a diagnosis. METHODS Homeless (n = 559) and housed (n = 2002) individuals newly diagnosed with dementia were matched on age, sex, diagnosis date, and health region within the ...
Salimah Z. Shariff   +4 more
wiley   +1 more source

Effect of Idalopirdine as Adjunct to Cholinesterase Inhibitors on Change in Cognition in Patients With Alzheimer Disease: Three Randomized Clinical Trials

open access: yesJournal of the American Medical Association (JAMA), 2018
A. Atri   +8 more
semanticscholar   +1 more source

Cholinergic Degeneration and Cognitive Function in Early GBA1‐Related Parkinson's Disease

open access: yesAnnals of Neurology, Volume 98, Issue 2, Page 398-409, August 2025.
Objective The phenotype of patients with Parkinson's disease carrying GBA1 variants (GBA‐PD) suggest similarities to symptomatology associated with early cholinergic system degeneration. Therefore, this study aims to investigate the clinical features and the cholinergic innervation pattern in patients with early GBA‐PD versus those without the GBA1 ...
Sofie Slingerland   +6 more
wiley   +1 more source

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