Results 141 to 150 of about 12,394 (186)

Inhibition of cyclooxygenase-2 impacts chondrocyte hypertrophy [PDF]

Osteoarthritis and Cartilage, 2012
Caron, M.J., Emans, P.J., Janssen, M.P., Sanen, K., Coolsen, M.M., Voss, L., Surtel, D.A., Cremers, A., Voncken, J.-W., Welting, T.J., van Rhijn, L.W.   +10 more
openaire   +1 more source

PTHrP targets salt-inducible kinases, HDAC4 and HDAC5, to repress chondrocyte hypertrophy in the growth plate. [PDF]

Bone, 2021
Nishimori S, Wein MN, Kronenberg HM.
europepmc   +1 more source

Viscoelastic response of cells and the role of actin cytoskeletal remodelling.

, 2012
PhDThe mechanical properties of living cells provide useful information on cellular structure and function. In the present study a micropipette aspiration technique was developed to investigate the viscoelastic parameters of isolated articular ...
Pravincumar, Priyanka
core  

Chemokine (C-C Motif) Ligand 2/Chemokine Receptor 2 (CCR2) Axis Blockade to Delay Chondrocyte Hypertrophy as a Therapeutic Strategy for Osteoarthritis. [PDF]

Med Sci Monit, 2021
Wang Z, Wang B, Zhang J, Wu Z, Yu L, Sun Z.   +5 more
europepmc   +1 more source

CHARACTERIZING AQP9: A REGULATOR OF EPIPHYSEAL PLATE CHONDROCYTE PROLIFERATION, HYPERTROPHY, AND LONG BONE GROWTH

, 2018
Aquaporin-9 (AQP9) is a membrane channel protein suspected to regulate growth in the epiphyseal plate. As long bone defects often possess limited non-surgical options, novel factors underlying bone growth must be continuously explored to advance ...
Tang, Pontius
core   +1 more source

Osteoarthritis-Related Inflammation Blocks TGF-β's Protective Effect on Chondrocyte Hypertrophy via (de)Phosphorylation of the SMAD2/3 Linker Region. [PDF]

Int J Mol Sci, 2021
Thielen N, Neefjes M, Wiegertjes R, van den Akker G, Vitters E, van Beuningen H, Blaney Davidson E, Koenders M, van Lent P, van de Loo F, van Caam A, van der Kraan P.   +11 more
europepmc   +1 more source

Molecular Mechanisms of Chondrocyte Hypertrophy Mediated by Physical Cues and Therapeutic Strategies in Osteoarthritis. [PDF]

Int J Mol Sci
Jin GZ.
europepmc   +1 more source

COX-2 in Fracture Callus Chondro-Osseous Junction Osteoclasts Regulates Chondrocyte Hypertrophy and Callus Vasculogenesis. [PDF]

J Orthop Res
Teitelbaum M, Lin HN, Culbertson MD, Wetterstrand C, Patrick O'Connor J.   +4 more
europepmc   +1 more source

ELR+ CXC chemokine signalling in cartilage homeostasis.

, 2011
PhDThe production of ELR+ CXC chemokines is widely studied in arthritis and has been postulated to contribute to the inflammatory phenomena that eventually lead to cartilage breakdown.
Sherwood, Joanna
core  

Undercarboxylated OCN Inhibits Chondrocyte Hypertrophy and Osteoarthritis Development through GPRC6A/HIF-1α Cascade. [PDF]

Int J Biol Sci
Du Z, Zhao Y, Zhang K, Qin Q, Luo C, Wu J, Zhang H, Liu S, Xu Z, Zheng J, Fan S, Jiang X, Li X, Wang Y.   +13 more
europepmc   +1 more source