Results 251 to 260 of about 48,883 (320)

Function and regulation of transforming growth factor β1 signalling in antler chondrocyte proliferation and differentiation. [PDF]

Cell Prolif, 2019
Ma L, Yang ZQ, Ding JL, Liu S, Guo B, Yue ZP.   +5 more
europepmc   +1 more source

Development of Bioactive 3D Printed MC/Al/Gel/HA Scaffolds with Enhanced Printability, Flexibility and Mechanical Strength

Macromolecular Materials and Engineering, EarlyView.
This study presents the development of a 3D printable, bioactive hydrogel scaffold by incorporating methylcellulose (MC) and hydroxyapatite (HA) into an alginate/gelatin (AlGel) system. The scaffolds are characterized in terms of their rheological behavior, structural stability, degradation behavior, mechanical performance, cytocompatibility, and ...
Mehmet Ali Karaca, Özgül Gök, Duygu Ege   +2 more
wiley   +1 more source

Downregulated miR‑302d‑3p promotes chondrocyte proliferation and migration by regulation of Unc‑51‑like kinase 1. [PDF]

Int J Mol Med, 2019
Wang S, Zheng Y, Hu Z, Wang Z, Zhang Y, Wei L.   +5 more
europepmc   +1 more source

Cell Apoptosis and Glucocorticoid‐Induced Osteonecrosis

Med Research, EarlyView.
The review identifies glucocorticoid‐induced osteocyte/osteoblast apoptosis as central to femoral head osteonecrosis (GION), mediated through STAT1‐caspase‐3, PI3K/Akt, Wnt/β‐catenin, and oxidative stress pathways. Emerging therapies targeting these pathways (e.g., HIF‐1α stabilization, AMPK activation, and exosome‐mediated miRNA delivery) show ...
Xiumei Tang, Yanyun Pang, Peijia Zhu, Zhengdong Zhang, Sen Guo, Zhijian Wei, Wenzhao Wang, Bin Ning   +7 more
wiley   +1 more source

Advances in Molecularly Imprinted Polymers for Bone Biomarker Detection and Therapeutic Applications

ChemistryOpen, EarlyView.
This review highlights the emerging applications of molecularly imprinted polymers (MIPs) in bone regeneration and diagnosis. MIPs facilitate osteogenic treatments by guiding stem cell differentiation and delivering bioactive molecules and enable precise detection of bone turnover biomarkers via MIP‐based sensors, offering promising strategies for next‐
Ren Yang, Xiaohan Ma, Mingcheng Xuan, Yingqi Ma, Jiexian Ding, David Y. S. Chau, Jonathan C. Knowles, Feng Peng, Alessandro Poma   +8 more
wiley   +1 more source

Glucosamine promotes chondrocyte proliferation via the Wnt/β‑catenin signaling pathway. [PDF]

Int J Mol Med, 2018
Ma Y, Zheng W, Chen H, Shao X, Lin P, Liu X, Li X, Ye H.   +7 more
europepmc   +1 more source

Anti‐Inflammatory/Antioxidant Features of Adipose Tissue Mesenchymal Stem Cells Conditioned Media for Doped TiO2 Nanoparticles in Induced Inflammation

ChemistryOpen, EarlyView.
The PI3K/AKT pathway is triggered when lipopolysaccharide (LPS) binds to TLR4 on the cell membrane. This causes the NF‐κB complex to get phosphorylated and IKB to degrade, allowing NF‐κB to go into the nucleus. Pro‐inflammatory genes including interleukin‐4 (IL‐4), IL‐6, and tumor necrosis factor α are triggered by this.
Ahmed A. Abd‐Rabou, Ahmed M. Youssef, Mohamed I. El‐Khonezy, Soheir E. Kotob, Mohamed S. Kishta   +4 more
wiley   +1 more source

Suv39h1 promotes facet joint chondrocyte proliferation by targeting miR-15a/Bcl2 in idiopathic scoliosis patients. [PDF]

Clin Epigenetics, 2019
Li J, Yang G, Liu S, Wang L, Liang Z, Zhang H.   +5 more
europepmc   +1 more source

Teratoid Hepatoblastoma: Clinicopathologic Features and Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Teratoid hepatoblastoma (HB) is a rare histologic subtype of the most common pediatric liver cancer. Understanding of the clinicopathologic features and outcomes of patients with this disease is currently limited. Methods Multi‐institution, retrospective chart review was conducted to compare 20 children with teratoid HB to 129 ...
Brian T. Hickner, Andres F. Espinoza, Soo Jin Cho, Stephen Sarabia, Martin Urbicain, Ann Wang, Sanjeev A. Vasudevan, Dolores H. López‐Terrada, Kalyani R. Patel   +8 more
wiley   +1 more source

Does Nimodipine, a Selective Calcium Channel Blocker, Impair Chondrocyte Proliferation or Damage Extracellular Matrix Structures? [PDF]

Curr Pharm Biotechnol, 2019
Kaplan N, Yilmaz I, Karaarslan N, Kaya YE, Sirin DY, Ozbek H.   +5 more
europepmc   +1 more source