Results 61 to 70 of about 48,883 (320)
Development of fibrocartilage layers in the anterior cruciate ligament insertion in rabbits
Background A detailed evaluation focusing on the fibrocartilage layers in the anterior cruciate ligament (ACL) insertion is necessary to consider regeneration of the insertion.
Hirotaka Mutsuzaki+3 more
doaj +1 more source
Perichondrial expression of Wdr5 regulates chondrocyte proliferation and differentiation
Wdr5 is developmentally expressed in osteoblasts and is required for osteoblast differentiation. Mice overexpressing Wdr5 under the control of the mouse alpha(1)I collagen promoter (Col I-Wdr5) display accelerated osteoblast differentiation as well as accelerated chondrocyte differentiation, suggesting that overexpression of Wdr5 in osteoblasts affects
Francesca Gori+2 more
openaire +3 more sources
Human stem cells and articular cartilage regeneration. [PDF]
The regeneration of articular cartilage damaged due to trauma and posttraumatic osteoarthritis is an unmet medical need. Current approaches to regeneration and tissue engineering of articular cartilage include the use of chondrocytes, stem cells ...
Inui, Atsuyuki+2 more
core +4 more sources
Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana+2 more
wiley +1 more source
Objective: to study the effect of a conditioned medium of mesenchymal stromal cells (MSCs) from different sources on human chondrocyte proliferation.Materials and methods.
A. D. Belova+8 more
doaj +1 more source
In vitro exposure of human chondrocytes to pulsed electromagnetic fields
The effect of pulsed electromagnetic fields (PEMFs) on the proliferation and survival of matrix-induced autologous chondrocyte implantation (MACI®)-derived cells was studied to ascertain the healing potential of PEMFs.
V Nicolin+7 more
doaj +1 more source
Integrin‐linked kinase regulates chondrocyte shape and proliferation [PDF]
The interaction of chondrocytes with the extracellular‐matrix environment is mediated mainly by integrins. Ligated integrins are recruited to focal adhesions (FAs) together with scaffolding proteins and kinases, such as integrin‐linked kinase (Ilk). Ilk binds the cytoplasmic domain of β1‐, β2‐ and β3‐integrins and recruits adaptors and kinases, and is ...
Reinhard Fässler+4 more
openaire +3 more sources
Distinct metabolic programs induced by TGF-β1 and BMP2 in human articular chondrocytes with osteoarthritis [PDF]
Objectives: Cellular energy metabolism is important for the function of all tissues, including cartilage. Recent studies indicate that superficial and deep subpopulations of articular chondrocytes (ACs) have distinct metabolic profiles.
O\u27Keefe, Regis J+3 more
core +3 more sources
A visible light‐responsive polyacrylamide‐azobenzene hydrogel enables safe, reversible stiffness control for studying cell mechanobiology without harmful UV exposure. This approach reveals stem cells respond rapidly to mechanical changes, showing altered shape and protein distribution within one hour.
Aafreen Ansari+11 more
wiley +1 more source
miR-29b inhibits TGF-β1-induced cell proliferation in articular chondrocytes
Transforming growth factor β1 (TGF-β1) is a known regulator of chondrocyte proliferation and promotes cartilage repair in osteoarthritis (OA). microRNA-29b-3p (miR-29b-3p) is downregulated by TGF-β1 and overexpressed in OA cartilage. However, the ability
Masahiro Horita+4 more
doaj